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A-Plus NG Tablet

Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 23 Feb 2026 | 11:40 AM (IST)
A-Plus NG Tablet is a combination medicine used for the treatment of neuropathic pain. This medicine decreases the pain by stopping the movement of pain signals to the brain.
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Gabipenta-NT 400 Tablet
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A-Plus NG Tablet
A-Plus NG Tablet
strip of 10 tablets
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Same composition
Gabipenta-NT 400 Tablet
Gabipenta-NT 400 Tablet
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by Leeford Healthcare Ltd
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₹12.9 per tablet

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A-Plus NG Tablet image
A-Plus NG Tablet image
A-Plus NG Tablet image
A-Plus NG Tablet image
A-Plus NG Tablet image

Product introduction

A-Plus NG Tablet is taken by mouth, with or without food, and preferably at night. It is advised to take it at a fixed time each day to maintain a consistent level of medicine in the blood. In case you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop taking this medicine suddenly without talking to the doctor, as it may worsen your symptoms.


Some common side effects of this medicine are constipation, difficulty in urination, weight gain, tiredness, and dryness in the mouth. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may cause weight gain, and to control it, you should exercise regularly and follow a balanced diet. Remember to inform the doctor if you develop any unusual mood changes, as this medicine may lead to suicidal thoughts.


Before taking this medicine, let your doctor know if you suffer from kidney or liver disease. Your doctor should also know about all other medicines you are taking, as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Uses of A-Plus NG Tablet

Benefits of A-Plus NG Tablet

Treatment of Neuropathic pain
A-Plus NG Tablet is a combination medicine used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles, or spinal cord injury. It reduces pain and its associated symptoms, including mood changes, sleep disturbances, and fatigue.

Side effects of A-Plus NG Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of A-Plus NG
  • Sleepiness
  • Tiredness
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Increased heart rate
  • Uncoordinated body movements
  • Constipation
  • Difficulty in urination
  • Weight gain
  • Dizziness
  • Blurred vision
  • Dryness in mouth
  • Impotence
  • Indigestion
  • Insomnia (difficulty in sleeping)
  • Decreased white blood cell count
  • Peripheral edema
  • Weakness

How to use A-Plus NG Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. A-Plus NG Tablet may be taken with or without food.

How A-Plus NG Tablet works

A-Plus NG Tablet is a combination of two medicines: Gabapentin and Nortriptyline. Gabapentin is an alpha 2 delta ligand that decreases the pain by modulating calcium channel activity of the nerve cells. Nortriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Together, they alleviate neuropathic pain (pain caused by damaged nerves).

Quick tips

  • A-Plus NG Tablet is used to treat certain types of long-lasting pain caused by damage to nerves.
  • Inform your doctor if you are taking any other pain-relieving medicines.
  • Along with taking this medicine, your doctor might advise you to undergo physiotherapy to get relief from pain.
  • Avoid taking antacids 2 hours before or after taking A-Plus NG Tablet as they make it harder for your body to absorb the medicine.

Safety advice

Alcohol

Alcohol

UNSAFE
Do not drink alcohol while you are taking this medicine. A-Plus NG Tablet may cause excessive drowsiness when taken with alcohol.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Information regarding the use of A-Plus NG Tablet during pregnancy is not available. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of A-Plus NG Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

UNSAFE
A-Plus NG Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
A-Plus NG Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
A-Plus NG Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine. Use of A-Plus NG Tablet is not recommended in patients with severe liver disease.

Frequently asked questions

A-Plus NG Tablet is a combination of two medicines used to treat nerve pain (neuropathic pain). It calms the damaged or overactive nerves by acting on the brain. Thereby, it decreases the pain sensation.
No, you should not stop taking A-Plus NG Tablet even if your pain is relieved. Continue to take it as advised by your doctor. If you suddenly stop taking A-Plus NG Tablet, you may experience withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain and sweating. You may need to gradually taper the dose before you stop the medication completely.
A-Plus NG Tablet can make you feel hungry which might make you eat more, thereby increasing your chances of putting on weight. However, preventing weight gain is easier than losing the increased weight. Try to eat a healthy balanced diet without increasing your portion sizes (per-meal intake). Do not eat food items that contain a lot of calories, such as soft drinks, oily food, chips, cakes, biscuits, and sweets. If you feel hungry between meals avoid eating junk food and eat fruits, vegetables and low-calorie foods. Regular exercise will help prevent weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight.
The use of A-Plus NG Tablet can affect the sexual life of both men and women. Most commonly observed problems are decreased sexual desire, erectile dysfunction (inability to develop or maintain erection during the sexual activity) and inability to reach orgasm. It can also cause a decrease in satisfaction and cause discomfort while intercourse. If you experience these problems, discuss them with your doctor but do not stop taking A-Plus NG Tablet.
Serious side effects because of A-Plus NG Tablet are uncommon and rare. Consult your doctor immediately if you notice any of the following: changes in body temperature, difficulty in breathing, increased heartbeat (palpitations), weakness, unsteadiness when walking, reduced coordination or slowed reactions, unusual changes in mood or behavior (such as restlessness, nervousness or excitement), signs of depression, seeing or hearing things that are not there, irrational thinking, blurred or double vision, uncontrollable jerky eye movements, difficulty seeing, signs of frequent infections such as fever, severe chills, sore throat or mouth ulcers. These side effects are uncommon but may be serious and need urgent medical attention.
An initial benefit with A-Plus NG Tablet may be seen after 2 weeks of treatment. However, it may take around 2-3 months to see full benefit. It may even take longer in some patients.
If you forget to take the scheduled dose of A-Plus NG Tablet and it is almost time for your next dose, skip the dose you missed and take your next dose at the scheduled time. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose you missed because this may increase the risk of unwanted side effect due to overdosage. If you are not sure what to do, ask your doctor about taking A-Plus NG Tablet.
In a situation like this, contact your doctor immediately or seek emergency help at the nearest hospital. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention. Overdose of this medicine may make you feel drowsy, weak, unsteady when walking, have double visions, slurred speech or diarrhea, confusion, blurred vision, dizziness, body temperature changes (low and high), difficulty in breathing and increased heartbeat.
A-Plus NG Tablet may impair your thinking or reactions. Be careful while driving or while doing any activity that requires you to be alert. Do not drink alcohol while you are taking A-Plus NG Tablet. It can increase the effects of alcohol which could be dangerous. Grapefruit and grapefruit juice may also interact with this medicine and cause unwanted side effects. Avoid exposure to sunlight or tanning beds. Use of A-Plus NG Tablet can make you more prone to sunburns. Wear protective clothing and use sunscreen when you are outdoors during daytime.
You may need to see your doctor regularly if you have started to take A-Plus NG Tablet. However, you must consult your doctor if the advised dosage of A-Plus NG Tablet does not improve your symptoms or if you continue experiencing unwanted side effects that affect your routine activities.
Yes, A-Plus NG Tablet may make you feel drowsy or may cause you to suddenly fall asleep during your daily activities. You might not even feel drowsy or have any other warning signs before you suddenly fall asleep. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities at the beginning of your treatment until you know how the medication affects you. Inform your doctor if you experience such episodes while you are taking this medicine.

Fact Box

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No

Therapeutic Class

NEURO CNS
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Domagk Smith Labs Pvt Ltd
Address: flot no. 31/36, near salwan public school, old rajinder nagar, new delhi-110060, delhi, india

Vendor Details

Country of origin: India
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