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Fixotic Advance (Fipronil) Tick and Flea Control Pet Spray

Fipronil (0.25% w/v)+ S-Methoprene (0.22% w/v)
Genuine
Authenticity Assured
Animal use
not for humans
Prescription
required
Fixotic Advance (Fipronil) Tick and Flea Control Pet Spray is a medicine used to treat and prevent parasitic infestations in dogs and cats. It effectively kills fleas, ticks, and lice, and also stops the growth of flea eggs, larvae, and pupae. It targets both adult and immature parasite stages and provides complete and long-lasting protection.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 22 May 2026 | 06:04 PM (IST)
₹400
₹498
20% off
100 ml Spray
Get by 2pm, Today
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Gurgaon
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Free Return

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within 7 days

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May, 2027

 
 
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General Information

Contains

Fipronil (0.25% w/v)+ S-Methoprene (0.22% w/v)

Marketer

Vetoquinol India Animal Health Pvt Ltd
The content is shown in English
Fixotic Advance (Fipronil) Tick and Flea Control Pet Spray image
Fixotic Advance (Fipronil) Tick and Flea Control Pet Spray image

Your pet's medicine at a glance

Fixotic Advance (Fipronil) Tick and Flea Control Pet Spray should be used as per your veterinarian’s advice. Part the fur at the base until the skin is visible and apply the contents directly onto the skin. Ensure the application site is dry before allowing your pet to mix with others or be handled. To get the most benefit, apply as often as the veterinarian has instructed. Clean the vacuum, the beddings, carpets, and resting areas to help eliminate fleas from the environment and improve the treatment’s effectiveness.


Fixotic Advance (Fipronil) Tick and Flea Control Pet Spray is generally well-tolerated when used in the prescribed dose. However, some pets may experience mild skin reactions at the application site, such as redness, itching, hair loss, or scaling. Excessive salivation, temporary restlessness, or mild vomiting can also occur, usually if the animal licks the treated area. These symptoms are generally short-lived and resolve on their own.


Fixotic Advance (Fipronil) Tick and Flea Control Pet Spray is for external use only and should not be used on puppies or kittens younger than 8 weeks or on sick or recovering animals. Avoid contact with your pet’s eyes, mouth, and skin during application, and wash your hands thoroughly afterward. Prevent the treated animals from licking each other until the site is completely dry.

Uses of Fixotic Advance (Fipronil) Tick and Flea Control Pet Spray in pets

  • Treatment of Parasitic Infestations

Benefits of Fixotic Advance (Fipronil) Tick and Flea Control Pet Spray for your pet

Treatment of Parasitic Infestations
Fixotic Advance (Fipronil) Tick and Flea Control Pet Spray is effective against common external parasites such as fleas, ticks, lice, and mites in dogs and cats. It kills these parasites quickly and prevents their life cycle from continuing. This helps relieve itching, irritation, and skin infections as well as prevents more serious problems like flea allergy dermatitis and tick-borne diseases.

Side effects of Fixotic Advance (Fipronil) Tick and Flea Control Pet Spray in pets

Fixotic Advance (Fipronil) Tick and Flea Control Pet Spray does not pose serious side effects and is well-tolerated by pets. In case the side effects do occur, they're likely to subside once the body adapts to the medicine. Consult your pet's veterinarian if these side effects persist or bother your pet. The most common side effects include-
Common side effects of Fixotic
  • No common side effects seen

How can I give Fixotic Advance (Fipronil) Tick and Flea Control Pet Spray to my pet?

Apply the medicine in the dose and duration instructed by the veterinarian. Part the fur at the base until the skin is visible and apply directly to the skin.

How Fixotic Spray works

Fixotic Advance (Fipronil) Tick and Flea Control Pet Spray is a combination of two medicines: fipronil and (S)-methoprene. Fipronil acts on the parasites’ nervous system, causing paralysis and death of fleas, ticks, and lice when they come in contact with the treated pet. (S)-Methoprene prevents flea eggs and larvae from growing into adult fleas, breaking their life cycle. Together, they not only eliminate existing parasites but also stop new infestations, keeping pets healthy and itch-free for longer.

Quick tips

  • Apply Fixotic Advance (Fipronil) Tick and Flea Control Pet Spray only when your pet’s coat is completely dry, and avoid bathing or swimming for at least two days after treatment to maintain effectiveness.
  • Apply it directly to the skin between the shoulder blades, not on the fur, so it spreads properly across the body.
  • Treat all pets in the household on the same day to prevent reinfestation from untreated animals.
  • Wash or vacuum your pet’s bedding, carpets, and furniture regularly to remove flea eggs and larvae from the environment.
  • Do not allow pets to lick each other or the treated area until it is completely dry.
  • Avoid applying to broken or irritated skin to reduce the risk of reactions.

Safety advice

Pregnancy

Pregnancy

Fixotic Advance (Fipronil) Tick and Flea Control Pet Spray is generally considered safe to use in breeding and pregnant dogs and cats when used as directed. It can be applied during all reproductive stages without affecting fertility or pregnancy outcomes.
Breast feeding

Breast feeding

Fixotic Advance (Fipronil) Tick and Flea Control Pet Spray can be safely used in lactating female dogs and cats. However, avoid direct contact between the nursing young and the treated application site until it is completely dry.
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established

Frequently asked questions

Fixotic Advance (Fipronil) Tick and Flea Control Pet Spray is generally applied once every month (about every 30 days) to maintain continuous protection. Consult your veterinarian for guidance.
After application, the medicine spreads across the skin and hair coat and begins to act, killing the adult fleas quickly and preventing the new fleas from developing. It generally provides about 30 days of protection in typical conditions.
Bathing or swimming soon after application may reduce the effectiveness of the medicine, because some of the topical solution can be washed off. It is recommended to avoid shampooing or wetting the coat for at least 24–48 hours after application to allow the medicine to disperse and bind properly.
Fixotic Advance (Fipronil) Tick and Flea Control Pet Spray is generally approved for use in puppies and kittens 8 weeks of age or older and above a minimum weight. Use in pregnant or nursing animals should be done under veterinary advice. It is generally considered safe in breeding, pregnant, and nursing animals. However, consult your veterinarian to ensure safety.
The application site should be in a place the animal cannot easily reach (often between the shoulder blades), and pets should not lick or groom that area until it is dry. Another animal in the household should also be prevented from licking the treated pet. Contact your veterinarian if you suspect excessive licking or ingestion of the product.
No. This medicine is not recommended for rabbits or small mammals. In fact, the active ingredient fipronil is known to be very toxic in rabbits.
There are no well-documented drug interactions for Fixotic Advance (Fipronil) Tick and Flea Control Pet Spray in dogs and cats. However, you should always inform your veterinarian of all medications, supplements, or topical treatments your pet is receiving before applying them to ensure safety.

Fact Box

Habit Forming

No

Therapeutic Class

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Vetoquinol India Animal Health Pvt Ltd
Address: 801, Sigma, 8th Floor, Hiranandani Business Park, Technology Street - Powai Mumbai, Maharashtra 400 076 India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Fixotic Advance (Fipronil) Tick and Flea Control Pet Spray. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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