Overview
Uses and benefits
Side effects
How to use
How drug works
Safety advice
Missed dose
All substitutes
Quick tips
Fact box
FAQs

Author Details

Written By

Dr. Sakshi Jain

MS, BDS

Reviewed By

Dr. Rajeev Sharma

MBA, MBBS

Last updated

06 Apr 2026 | 04:05 PM (IST)

We provide you with authentic, trustworthy and relevant information

Want to know more

Have issue with the content?

Report Problem

Enzoflam-SP Tablet

Prescription Required

Marketer

Alkem Laboratories Ltd

SALT COMPOSITION

Aceclofenac (100mg) + Paracetamol (325mg) + Serratiopeptidase (15mg)

Storage

Store below 25°C

61% cheaper alternative available with same salt composition

Click here to view all substitutes

Product introduction

Enzoflam-SP Tablet is a combination medicine that relieves muscle, joint, and postoperative pain. It effectively alleviates pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis.

Enzoflam-SP Tablet should be taken at the dose and duration advised by your doctor. It should be taken with food or milk to prevent stomach upset. Taking the medicine regularly at the correct times increases its effectiveness. It is important to continue taking it until your doctor tells you it is safe to stop.

Nausea, vomiting, stomach pain, indigestion, heartburn, increased liver enzymes, dizziness, drowsiness, and diarrhea are some common side effects that might be observed on taking this medicine. Your doctor may regularly monitor your kidney function, liver function, and blood component levels if you take this medicine for long-term treatment. Long-term use may lead to serious complications such as stomach bleeding and kidney problems. Enzoflam-SP Tablet is not recommended if you are pregnant or breastfeeding.

Take it as prescribed to get the most benefit. Do not take more or longer than needed, as that can be dangerous. In general, you should take the lowest dose that works for the shortest possible time. This will help you go about your daily activities more efficiently and have a better, more active quality of life.

Uses of Enzoflam-SP Tablet

Pain relief

Benefits of Enzoflam-SP Tablet

In Pain relief

Enzoflam-SP Tablet is a combination medicine used for short-term relief of pain, inflammation, and swelling in conditions affecting joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis. Along with painkillers, this medicine also contains an active ingredient called Serratiopeptidase, an enzyme that supports the overall healing process and speeds up recovery.

Side effects of Enzoflam-SP Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Enzoflam-SP

Nausea
Vomiting
Stomach pain
Indigestion
Heartburn
Loss of appetite
Diarrhea
Dizziness
Increased liver enzymes
Drowsiness

How to use Enzoflam-SP Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Enzoflam-SP Tablet should be taken with or after food.

How Enzoflam-SP Tablet works

Enzoflam-SP Tablet is a combination of three medicines: Aceclofenac, Paracetamol and Serratiopeptidase. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID), and Paracetamol is an antipyretic (fever reducer). They work by blocking the release of certain chemical messengers in the brain that cause pain and fever. Serratiopeptidase is an enzyme which works by breaking down abnormal proteins at the site of inflammation and promotes healing.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Enzoflam-SP Tablet

Pregnancy

UNSAFE

Enzoflam-SP Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

CONSULT YOUR DOCTOR

Enzoflam-SP Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Enzoflam-SP Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

UNSAFE

Enzoflam-SP Tablet is unsafe to use in patients with kidney disease and should be avoided.
Use of Enzoflam-SP Tablet is not recommended in patients with severe kidney disease.

Liver

UNSAFE

Enzoflam-SP Tablet is unsafe to use in patients with liver disease and should be avoided.
However, the use of Enzoflam-SP Tablet is not recommended in patients with severe liver disease and active liver disease.

What if you forget to take Enzoflam-SP Tablet?

If you miss a dose of Enzoflam-SP Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Enzoflam-SP Tablet

₹12.6/Tablet

Alcinac Forte 100mg/325mg/15mg Tablet

Leeford Healthcare Ltd

₹4.88/tablet

61% cheaper

Acimol-Forte Tablet

Leeford Healthcare Ltd

₹6.13/tablet

51% cheaper

Movexx SP Tablet

Cipla Ltd

₹7.35/tablet

42% cheaper

Nicip ASP 100mg/325mg/15mg Tablet

Cipla Ltd

₹7.35/tablet

42% cheaper

acemiz-S Tablet

Lupin Ltd

₹8.83/tablet

30% cheaper

View all substitutes

Quick tips

Take Enzoflam-SP Tablet after food to reduce stomach irritation.
Do not take Enzoflam-SP Tablet with other medicines containing paracetamol (acetaminophen), such as some cold or fever medicines, unless advised by your doctor.
Avoid combining Enzoflam-SP Tablet with other NSAID painkillers unless your doctor recommends it.
Avoid alcohol while taking Enzoflam-SP Tablet, as it may increase stomach irritation and the risk of liver damage.
Enzoflam-SP Tablet may cause dizziness or drowsiness, so avoid driving or operating machinery until you know how it affects you.
Stay well hydrated while using Enzoflam-SP Tablet, as dehydration may increase the risk of kidney-related side effects.
Inform your doctor if you have kidney disease, heart disease, asthma, stomach ulcers, or uncontrolled high blood pressure before taking Enzoflam-SP Tablet.
Seek urgent medical attention if you notice black stools, vomiting blood, severe stomach pain, or unusual bruising.
Stop taking Enzoflam-SP Tablet and seek medical help if you develop rash, swelling of the face, or breathing difficulty.
Use Enzoflam-SP Tablet only for the duration prescribed, and consult your doctor if pain, swelling, or fever persists despite treatment.
Tell your doctor if you are taking blood thinners, steroids, or certain antidepressants that may increase bleeding risk.

Fact Box

Habit Forming

Therapeutic Class

PAIN ANALGESICS

FAQs

What is Enzoflam-SP Tablet used for and how does it work?

Enzoflam-SP Tablet is used to relieve pain, swelling, and inflammation in conditions such as muscle injuries, joint pain, dental pain, or after surgery. It contains medicines that work together to reduce pain signals, lower inflammation, and decrease swelling, helping improve comfort and recovery when used as prescribed by a doctor.

Can I take Enzoflam-SP Tablet three times a day?

Enzoflam-SP Tablet should be taken only in the dose and frequency advised by your doctor. The correct dosing depends on the ingredients in Enzoflam-SP Tablet, the severity of your pain, and your overall health. Taking it more often than prescribed may increase the risk of stomach irritation, acidity, or other side effects.

Can I stop taking Enzoflam-SP Tablet when my pain is relieved?

Enzoflam-SP Tablet is usually used for short-term pain relief and may be stopped once the pain improves. However, if your doctor has advised you to continue it for a specific duration, follow their instructions and do not stop it earlier without medical advice.

What are the common side effects of Enzoflam-SP Tablet?

Enzoflam-SP Tablet may cause side effects such as stomach upset, nausea, vomiting, heartburn, dizziness, loose stools, or mild drowsiness in some people. These effects are usually mild and temporary. Taking it with food and staying well hydrated may help reduce stomach discomfort. Stop the medicine and seek medical help if you develop severe rash, breathing difficulty, black stools, or yellowing of the skin or eyes.

Can Enzoflam-SP Tablet be taken with vitamin B-complex?

Yes, Enzoflam-SP Tablet can generally be taken with vitamin B-complex supplements if advised by your doctor. While Enzoflam-SP Tablet helps relieve pain and inflammation, vitamin B-complex may support nerve health and help correct certain vitamin deficiencies.

Who should avoid Enzoflam-SP Tablet?

Enzoflam-SP Tablet should be avoided or used only under medical advice in people with allergy to painkillers, a history of stomach ulcers or bleeding, severe liver or kidney disease, uncontrolled high blood pressure, or heart failure. It is also generally not recommended during pregnancy, especially in the later stages.

What should I do if I miss a dose of Enzoflam-SP Tablet?

If you miss a dose of Enzoflam-SP Tablet, take the next scheduled dose at the usual time unless your doctor advises otherwise. Do not take two doses together to make up for a missed dose because this may increase the risk of side effects.

Can Enzoflam-SP Tablet be taken after food?

Enzoflam-SP Tablet is often easier on the stomach when taken after food. Taking it on an empty stomach may increase the chance of stomach irritation or acidity. Follow your doctor’s advice regarding the exact timing.

Can I drink alcohol while taking Enzoflam-SP Tablet?

It is generally best to avoid alcohol while using Enzoflam-SP Tablet because alcohol may increase the risk of stomach irritation, drowsiness, dehydration, or liver stress.

How long does Enzoflam-SP Tablet work?

The duration of relief from Enzoflam-SP Tablet can vary depending on the ingredients, the type of pain being treated, and individual response. It should always be used only for the duration advised by your doctor.

Is Enzoflam-SP Tablet good for nerve pain?

Enzoflam-SP Tablet may help relieve certain types of pain associated with inflammation or tissue injury. However, nerve pain can have different causes, and the suitability of Enzoflam-SP Tablet depends on your specific condition. Always consult your doctor for appropriate treatment.

Show less

Top Rheumatologists

5 ★

4.7 ★

4.5 ★

4.9 ★

MBBS, DNB, MD, Fellowship, Fellowship

4.7 ★

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Bhagat S, Agarwal M, Roy V. Serratiopeptidase: A systematic review of the existing evidence. Int J Surg. 2013;11(3):209-17. [Accessed 19 Apr. 2019] (online) Available from:
Taj Life Sciences. Aceclofenac, Paracetamol and Serratiopeptidase [Product Information]. [Accessed 12th Sept. 2023] (online) Available from:

Marketer details

Name: Alkem Laboratories Ltd

Address: Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.

Country of origin: India
Expires on or after: July, 2026

A licensed vendor partner from your nearest location will deliver Enzoflam-SP Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

MRP₹136.85 8% OFF

₹126

Inclusive of all taxes

10.0 tablets in 1 strip

The price displayed is the MRP (inclusive of applicable taxes). Any additional fee (such as shipping fee, handling and/or platform fee etc.) will be clearly disclosed before you complete your purchase.