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Written By
MDS, BDS
Reviewed By
MD (Pharmacology), MBBS
Last updated on:
15 Jan 2019 | 02:45 PM (IST)
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Overview

Introduction

1 Nvp Tablet is a combination of three medicines. This prescription medicine manages the feeling of nausea or vomiting during pregnancy. It blocks signals to reach the brain that trigger the feeling of nausea and vomiting.

1 Nvp Tablet is to be taken in the dose and duration advised by your doctor. You can take it with or without food, preferably at a fixed time.

This medication may make you feel dizzy or sleepy, so do not drive or do anything that requires mental focus. This medicine is generally well tolerated by patients. However, it may cause side effects like nausea, dryness of mouth, and lightheadedness. Before taking the medicine always consult your doctor if you are pregnant, breastfeeding or if you are suffering from any severe stomach, liver, kidney disease, or any known disease. You must stop this medication and consult your doctor in case you encounter any allergic reactions such as skin rash, swelling, and itching.

1 Nvp Tablet side effects

Common
  • Dryness in mouth
  • Constipation
  • Drowsiness
  • Lightheadedness

How to use 1 Nvp Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. 1 Nvp Tablet is to be taken with food.

How 1 Nvp Tablet works

1 Nvp Tablet is a combination of three medicines: doxylamine, vitamin B6 (pyridoxine) and folic acid, which treats nausea and vomiting associated with pregnancy. Doxylamine is an antihistamine which works by blocking the action of a chemical messenger (histamine), thereby controlling nausea, vomiting, and dizziness. Pyridoxine (vitamin B6) is a form of vitamin B which possesses anti-nausea properties. Folic is also a form of vitamin B which provides essential nutrients.

1 Nvp Tablet related warnings

Alcohol
CAUTION
Caution is advised when consuming alcohol with 1 Nvp Tablet. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
1 Nvp Tablet is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.
Lactation
SAFE IF PRESCRIBED
1 Nvp Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Larger doses or prolonged use of 1 Nvp Tablet may cause sleepiness and other effects in the baby
Driving
UNSAFE
1 Nvp Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
1 Nvp Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of 1 Nvp Tablet may not be needed in these patients. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
1 Nvp Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of 1 Nvp Tablet may not be needed in these patients. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
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Expert Advice

  • 1 Nvp Tablet helps treat nausea and vomiting in pregnant women whose symptoms did not improved using diet and lifestyle changes. 
  • Take it on an empty stomach with a glass of water.
  • It may cause dizziness. Do not drive or do anything requiring concentration until you know how it affects you.
  • Do not take it with other sedating medications such as cough and cold medications as the combination could worsen dizziness leading to falls or other accidents
  • Do not take 1 Nvp Tablet while breastfeeding.

Patient Concerns

Questions Related to 1 Nvp

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Hello Doctor, This consultation is regarding my father who has been a diabetic patient for the last 18 years now. His diabetes was always under control and he regularly took two tablets to maintain the sugar level. This was continued till he started avoiding to go to a doctor for a health check up and change in medicines. And then in 2014 his sugar levels started fluctuating s lot. He then visited a different doctor who for some reason started prescribing him a heavy dose of insulin and a bunch of tablet that included Januvia 50, Vogli 0.3, and about 10units of Human Mixtard 50 in the morning and 15 units of the same insulin before dinner. This has been keeping his sugar levels under control but I am really worried about him taking this Insulin every day to keep his sugar level controlled. My question and concern is regarding the same, that can this not be avoided and aren't there any other alternative to taking insulin. He doesn't even have Type 1 diabetes.
Dr. Sanjay Bhatt
Diabetes Specialist
Insulin is safe and best medicine rather than oral.so let him continue same
I am type 1 diabetes and pregnant with 21 week I offen get urine unfectie I had admitted to n was kept on drip an now. Doctor had given some antibiotics its 5 day course now 3 day pas I still fell the pain please guid
Dr. Sanjay Bhatt
Diabetes Specialist
Take a course of seven days and maintain hygiene.
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User Feedback


FAQs

Q. What are the instructions for storage and disposal of 1 Nvp?

Keep this medicine in the container or the pack it came in, tightly closed. Store it at as mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. Can I take a higher than the recommended dose of this medicine?

No, taking a higher than the recommended dose of 1 Nvp can cause increased side effects. If you are experiencing increased severity of nausea or vomiting, which is not relieved by the recommended doses, please consult your doctor for re-evaluation.

Q. Can the use of 1 Nvp cause drowsiness or sleepiness?

Yes, one of the common side effects of 1 Nvp is drowsiness. Do not drive, operate heavy machinery or engage in other activities that need your full attention. Do not drink alcohol or take any medicines that may depress the central nervous system like cough and cold medicines, certain pain medicines, and medicines that help you sleep, while you are taking 1 Nvp. Severe drowsiness can happen or it can become worse and cause falls or accidents.

Q. Can I breastfeed while taking 1 Nvp?

No, it is not advisable to breastfeed while using 1 Nvp. This medicine can pass into the breast milk and may harm the baby. Inform your doctor that you are breastfeeding if you are advised to take this medicine.

Q. Can the use of 1 Nvp cause dry mouth?

Yes, the use of 1 Nvp can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night. Try to avoid foods that are acidic (like lemons), spicy and salty.

Q. Can a pregnant woman take 1 Nvp?

Yes, it is safe to take 1 Nvp in pregnant women. In fact, this medicine is used to treat nausea and vomiting in pregnant women. It is mainly recommended to those women whose symptoms have not improved after changing their diet or using other non-medicine treatments.
Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Doxylamine succinate and pyridoxine hydrochloride. Blainville, Québec: Duchesnay Inc.; 1976 [revised Nov. 2016]. [Accessed 12 Apr. 2019] (online) Available from:External Link
  2. DailyMed. Doxylamine succinate and pyridoxine hydrochloride. [Accessed 12 Apr. 2019] (online) Available from:External Link
  3. ScienceDirect. Vitamin B6. [Accessed 12 Apr. 2019] (online) Available from:External Link
  4. DailyMed. Pyridoxine hydrochloride. [Accessed 12 Apr. 2019] (online) Available from:External Link
  5. Folic Acid. Maidenhead: Intrapharm Laboratories Limited; 2011 [revised 8 May 2018]. [Accessed 12 Apr. 2019] (online) Available from:External Link
  6. Folic Acid. Whiddon Valley: Actavis UK Limited; 1987 [revised 01 Mar. 2019]. [Accessed 12 Apr. 2019] (online) Available from:External Link
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