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MBA, MBBS
Last updated
06 Nov 2025 | 02:01 AM (IST)

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Apoquel 16mg Pet Tablet

rx_imgPrescription Required
animal only tagAnimal use only
SALT COMPOSITION
Oclacitinib (16mg)
Storage
Store below 30°C

Your pet's medicine at a glance

Apoquel 16mg Pet Tablet is a medicine used in dogs to control itching and inflammation caused by allergic dermatitis, as well as to manage the symptoms of atopic dermatitis. It helps relieve itching, redness, and irritation, allowing the skin to heal and improve comfort and quality of life in affected dogs.

Give Apoquel 16mg Pet Tablet in the dose and duration prescribed by your veterinarian. It can be given with or without food. To get the best results, continue the treatment exactly as prescribed and do not stop suddenly without your veterinarian’s advice. Regular check-ups and maintaining a clean, allergen-free environment further support the treatment outcomes.


Common side effects of Apoquel 16mg Pet Tablet include skin infections (pyoderma), vomiting, diarrhea, and loss of appetite. Most effects are temporary and resolve without treatment. If your dog shows unusual symptoms such as persistent vomiting, loss of appetite, or signs of infection, contact your veterinarian promptly.


Apoquel 16mg Pet Tablet should not be used in dogs less than 12 months old, those weighing under 3 kg, or dogs with immune suppression, or cancer, as the medicine may worsen these conditions. It is not recommended for use in pregnant or nursing animals or in dogs intended for breeding. Since this medicine can lower immune defenses, dogs on long-term treatment should be monitored for signs of infection or tumor growth.


Benefits of Apoquel 16mg Pet Tablet for your pet

In Control of Atopic dermatitis

In dogs with atopic dermatitis, Apoquel 16mg Pet Tablet helps control chronic itching, redness, and skin inflammation caused by environmental allergens such as pollen, dust, or mites. It offers long-term comfort by balancing the immune response that drives allergic skin reactions. When used as prescribed, it helps reduce flare-ups, minimizes the need for steroids, and promotes better skin condition. As a result, dogs with atopic dermatitis experience less discomfort, improved sleep, and a better overall quality of life.

In Control of Pruritus Associated with Allergic Dermatitis

Apoquel 16mg Pet Tablet provides fast relief from itching caused by allergic dermatitis in dogs. It targets the enzymes responsible for triggering itch and inflammation and helps reduce scratching, licking, and skin irritation within hours of dosing. This quick relief allows damaged skin to heal, prevents secondary infections, and improves the dog’s comfort and mood. When used correctly, it can help manage allergy flare-ups and keep your dog’s skin healthier and irritation-free.

Side effects of Apoquel 16mg Pet Tablet in pets

Apoquel 16mg Pet Tablet does not pose serious side effects and is well-tolerated by pets. In case the side effects do occur, they're likely to subside once the body adapts to the medicine. Consult your pet's veterinarian if these side effects persist or bother your pet. The most common side effects include-

Common side effects of Apoquel

  • Pyoderma
  • Skin swelling
  • Vomiting
  • Diarrhea
  • Loss of appetite

How can I give Apoquel 16mg Pet Tablet to my pet?

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it.

How Apoquel Tablet works

Apoquel 16mg Pet Tablet contains oclacitinib, a medicine that works by blocking specific enzymes called Janus kinases (JAKs) involved in the signaling pathways responsible for itching and inflammation. It inhibits these enzymes and prevents the release of chemical messengers that trigger allergic reactions and cause itching and redness. This reduces discomfort and skin irritation without broadly suppressing the immune system, helping dogs feel relief from itching and inflammation caused by allergic and atopic dermatitis.

Safety advice

Pregnancy
The safety of Apoquel 16mg Pet Tablet has not been evaluated in pregnant dogs. It should be used during pregnancy only if specifically recommended by a veterinarian after weighing potential benefits and risks.
Breast feeding
The safety of Apoquel 16mg Pet Tablet has not been evaluated for lactating dogs. It is unknown whether the medicine passes into milk. Use during lactation is not recommended unless advised by a veterinarian.
Kidney
There is limited data available on the use of Apoquel 16mg Pet Tablet in dogs with kidney disease. Please consult your doctor.
Liver
Since this medicine is metabolized in the liver, dogs with liver disease should receive Apoquel 16mg Pet Tablet only under veterinary supervision. Periodic liver function monitoring may be advised during long-term use to ensure safety.

What if I forget to give Apoquel 16mg Pet Tablet to my pet?

If you miss giving a dose of Apoquel 16mg Pet Tablet, administer it as soon as you remember. If it is nearly time for the next scheduled dose, skip the missed one and continue with the regular dosing schedule. Do not double the dose to make up for the missed dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Give Apoquel 16mg Pet Tablet exactly as prescribed by your veterinarian. Do not change the dose or frequency on your own.
  • Try to give the medicine at the same time every day to maintain steady control of itching.
  • Apoquel 16mg Pet Tablet can be given with or without food; if your dog vomits after dosing, try giving it with a small meal.
  • Keep your dog’s environment clean and free from allergens such as dust, fleas, and molds to enhance results.
  • Avoid giving Apoquel 16mg Pet Tablet to dogs younger than 12 months or with serious infections, unless directed by your veterinarian.
  • Wash your hands thoroughly after handling the medicine to ensure safety.

Fact Box

Chemical Class
Benzonitrile derivative
Habit Forming
No
Therapeutic Class
DERMA
Action Class
Janus kinase inhibitors

FAQs

What is Apoquel 16mg Pet Tablet used for?

Apoquel 16mg Pet Tablet is used in dogs to control itching and inflammation caused by allergic dermatitis and atopic dermatitis. It helps relieve symptoms such as itchiness, redness, and skin irritation associated with allergies.

How fast does Apoquel 16mg Pet Tablet start working?

Apoquel 16mg Pet Tablet starts reducing itching within 4 hours of the first dose, with significant improvement in most dogs within 24 hours.

Can Apoquel 16mg Pet Tablet be used long-term?

Yes, Apoquel 16mg Pet Tablet can be used long-term under veterinary supervision for the management of chronic atopic dermatitis. Regular check-ups are recommended to monitor your dog’s health during prolonged use.

Can Apoquel 16mg Pet Tablet be given with other medicines?

Apoquel 16mg Pet Tablet can be safely used alongside many common medicines, including antibiotics, anti-parasitics, and anti-inflammatory drugs. However, always inform your veterinarian about any other treatments your dog is receiving.

Is Apoquel 16mg Pet Tablet safe for all dogs?

Apoquel 16mg Pet Tablet should not be used in dogs under 12 months of age, or those with cancer, immune-related disorders, or severe infections. It is not recommended for breeding, pregnant, or nursing dogs.

Will Apoquel 16mg Pet Tablet cure my dog’s allergy?

Apoquel 16mg Pet Tablet does not cure allergies. But it can help manage the symptoms such as itching and inflammation. Identifying and controlling the underlying cause of the allergy (like food, dust, or fleas) will help achieve the best long-term results.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Oclacitinib [Prescribing Information]. Kalamazoo, MI: Zoetis Inc.; 2020. [Accessed 06 Nov. 2025] (online) Available from: External Link
  2. Oclacitinib [Summary of Product Characteristics]. Louvain-La-Neuve, Belgium: Zoetis Belgium; 2023. [Accessed 06 Nov. 2025] (online) Available from: External Link

Marketer details

Name: Zoetis India Limited
Address: 31, 3Rd Floor, Kalpataru Synergy, Opp. : Grand Hyatt, Santacruz(E) Mumbai Mumbai City Mh 400055 In / Godown No. 1 & 2, Bldg. No 12B, Prithvi Complex, Reti Bunder Road, Kalbar, Tah Bhiwandi -421302, Dist. Thane
Country of origin: United states

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