Macrozide is an antibiotic. It is used in combination with other antibiotics in the treatment of tuberculosis
Q. Is Macrozide bactericidal?
Macrozide is both a bacteriostatic and a bactericidal antibiotic. It stops the growth of bacteria (bacteriostatic) in certain cases and kills (bactericidal) the tuberculosis causing bacteria in other cases
Q. How does Macrozide work/treat tuberculosis?
Macrozide kills or stops growth of bacteria that causes tuberculosis (Mycobacterium tuberculosis). The exact mechanism of action for Macrozide is not known
Q. How does Macrozide cause hyperuricemia and gout?
Following oral intake of Macrozide, it gets converted in the body to pyrazinoic acid (active chemical form of Macrozide). Pyrazinoic acid blocks the excretion of urates (salt form of uric acid) by the kidneys. This causes an increase in blood levels of uric acid (hyperuricemia). Excess uric acid accumulation between joints causes pain, swelling, redness and stiffness in joints (gout).
Information last updated by Dr. Varun Gupta, MD Pharmacology on 16th Oct 2019. The medicine details are for information purpose only. Consult a doctor before taking any medicine.