Tacrolimus is an immunosuppressant. In organ transplant patients, it works by suppressing your body’s immune response helping your body to accept the new organ as if it were your own. In allergic eye disease, it works by decreasing the production of chemicals (eg. histamine) that cause allergic eye symptoms such as inflammation (redness and swelling).
Q. Which vaccines should not be taken while taking Keygraf?
You should avoid taking any live vaccines (vaccines that use pathogens that are still alive, but are attenuated, that is, weakened) while taking Keygraf. These may include vaccinations for measles, mumps, rubella, BCG (TB vaccine), yellow fever, chicken pox and typhoid. You should also avoid taking polio drops (by mouth) or flu vaccine (through nose).
Q. Who should not take Keygraf?
Patients who are allergic to it or have a weak immune system, high blood pressure and kidney failure should avoid Keygraf. This medicine should also be avoided in pregnant or breast-feeding women, and in people who plan to receive any live vaccines (e.g. MMR vaccine).
Q. What should I tell my doctor before taking Keygraf?
Inform your doctor if you are pregnant, have allergies, long-term infection, high blood sugar, or high blood pressure. You should also inform your doctor if you have high blood potassium levels or a weakened immune system. Tell your doctor if you have a history of any medication, have recently received or are scheduled to receive a live vaccine.
Q. Is Keygraf an antibiotic?
Yes, Keygraf is a type of antibiotic which belongs to a group of medicines called macrolides. It is mostly used after organ transplantation. This medicine’s immune-suppressing property helps prevent organ rejection after kidney, heart, or liver transplant.
Q. What should I be aware of before I start taking Keygraf?
This medicine suppresses the immune system and hence there is always an increased risk of infection. Moreover, in some cases, Keygraf can increase the risk of some kind of cancers like skin and lymph gland cancer (lymphoma). It can lower the ability of your immune system to fight infections. Consult your doctor before you start taking this medication and in case you notice any symptoms of infections like fever, sweats or chills, cough or flu-like symptoms, muscle aches, warm, red, or painful areas on your skin.
Q. Does Keygraf have an abuse potential?
No, Keygraf does not have abuse potential and thus, is not a controlled substance. Controlled substances have potential for abuse so they need permission from authorities and doctors for use.
Information last updated by Dr. Varun Gupta, MD Pharmacology on 20th Feb 2020. The medicine details are for information purpose only. Consult a doctor before taking any medicine.