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Glucomin-Plus

Composition for Glucomin-Plus Products

Glucomin-Plus Products are primarily used for
Type 2 diabetes mellitus

Products for Glucomin-Plus

MRP₹15
Not Available

About Glucomin-Plus Products

uses

Uses of Glucomin-Plus Products

Glibenclamide+Metformin is used in the treatment of type 2 diabetes mellitus.
side effects

Glucomin-Plus Products side effects

Common
Side Effects of Glucomin-Plus are Diarrhea, Nausea, Flatulence, Dizziness, Headache, Upper respiratory tract infection.

How Glucomin-Plus Products work

Glibenclamide + Metformin1 is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Glibenclamide + Metformin2 is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.

In Depth Information for Glucomin-Plus Products

  • Take it with food to lower your chance of having an upset stomach.
  • You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Glucomin-Plus.
  • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. 
  • Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
  • Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Glucomin-Plus may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Patient Concerns about Glucomin-Plus Products

Frequently asked questions about Glucomin-Plus Products

Q. What is Glucomin-Plus 5mg/500mg Tablet?

Glucomin-Plus 5mg/500mg Tablet is a combination of two medicines: Glibenclamide and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves the blood glucose levels in adults when taken along with proper diet and regular exercise. Glibenclamide lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of Type 1 DM.

Q. What is type 2 diabetes?

Type 2 diabetes is the most common form of diabetes. It is a condition in which the body is unable to make enough insulin, and the insulin produced by the body does not work well. When this happens, the glucose level in the blood rises and leads to serious medical problems. Symptoms of high blood sugar include frequent urination, increased thirst and increased hunger. Diabetes, if not treated properly, can cause long-term complications like neuropathy (nerve damage), nephropathy (kidney damage), eye damage (retinopathy), foot problems and also a higher risk of developing heart diseases.

Q. What are the possible side effects of Glucomin-Plus 5mg/500mg Tablet?

The use of Glucomin-Plus 5mg/500mg Tablet is associated with common side effects like hypoglycemia (low blood sugar level), nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use, it can also lead to vitamin B12 deficiency.

Q. Can the use of Glucomin-Plus 5mg/500mg Tablet cause hypoglycemia?

Yes, the use of Glucomin-Plus 5mg/500mg Tablet can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with this medicine. So, regular monitoring of blood sugar level is important. Always keep a quick source of sugar like glucose tablets, honey or fruit juice with you.

Q. Can the use of Glucomin-Plus 5mg/500mg Tablet lead to Vitamin B12 deficiency?

Yes, the use of Glucomin-Plus 5mg/500mg Tablet can cause vitamin B12 deficiency on long-term use as it interferes with the absorption of vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient may feel a tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of Vitamin B12 from outside sources at least once every year.

Q. Are there any specific conditions in which Glucomin-Plus 5mg/500mg Tablet should not to be taken?

The use of Glucomin-Plus 5mg/500mg Tablet should be avoided in patients with known allergy to any of the components or excipients of this medicine. It should also be avoided in patients with moderate to severe kidney disease and in patients with underlying metabolic acidosis including diabetic ketoacidosis.

Q. Is it safe to take alcohol while I am also taking Glucomin-Plus 5mg/500mg Tablet?

No, it is not safe to take Glucomin-Plus 5mg/500mg Tablet along with alcohol, as it may lower your low blood sugar levels (hypoglycemia) and can increase the chances of lactic acidosis.

Q. What are the instructions for storage and disposal of Glucomin-Plus 5mg/500mg Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. What is Glucomin-Plus 5mg/500mg Tablet?

Glucomin-Plus 5mg/500mg Tablet is a combination of two medicines: Glibenclamide and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves the blood glucose levels in adults when taken along with proper diet and regular exercise. Glibenclamide lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of Type 1 DM.

Q. What is type 2 diabetes?

Type 2 diabetes is the most common form of diabetes. It is a condition in which the body is unable to make enough insulin, and the insulin produced by the body does not work well. When this happens, the glucose level in the blood rises and leads to serious medical problems. Symptoms of high blood sugar include frequent urination, increased thirst and increased hunger. Diabetes, if not treated properly, can cause long-term complications like neuropathy (nerve damage), nephropathy (kidney damage), eye damage (retinopathy), foot problems and also a higher risk of developing heart diseases.

Q. What are the possible side effects of Glucomin-Plus 5mg/500mg Tablet?

The use of Glucomin-Plus 5mg/500mg Tablet is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use, it can also lead to vitamin B12 deficiency.

Q. Can the use of Glucomin-Plus 5mg/500mg Tablet cause hypoglycemia?

Yes, the use of Glucomin-Plus 5mg/500mg Tablet can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with this medicine. So, regular monitoring of blood sugar level is important. Always keep a quick source of sugar like glucose tablets, honey or fruit juice with you.

Q. Can the use of Glucomin-Plus 5mg/500mg Tablet lead to Vitamin B12 deficiency?

Yes, the use of Glucomin-Plus 5mg/500mg Tablet can cause vitamin B12 deficiency on long-term use as it interferes with the absorption of vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient may feel a tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of Vitamin B12 from outside sources at least once every year.

Q. Are there any specific conditions in which Glucomin-Plus 5mg/500mg Tablet should not to be taken?

The use of Glucomin-Plus 5mg/500mg Tablet should be avoided in patients with known allergy to any of the components or excipients of this medicine. It should also be avoided in patients with moderate to severe kidney disease and in patients with underlying metabolic acidosis including diabetic ketoacidosis.

Q. Is it safe to take alcohol while I am also taking Glucomin-Plus 5mg/500mg Tablet?

No, it is not safe to take Glucomin-Plus 5mg/500mg Tablet along with alcohol, as it may lower your low blood sugar levels (hypoglycemia) and can increase the chances of lactic acidosis.

Q. What are the instructions for storage and disposal of Glucomin-Plus 5mg/500mg Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Information last updated by Dr. Varun Gupta, MD Pharmacology on 25th Nov 2025.
The medicine details are for information purpose only. Consult a doctor before taking any medicine.