Thyroxine Binding Globulin near me in Varanasi

For men & women

Earliest reports in

96 hours

Contains

1 test

Know more about this test

TBG (Thyroxine Binding Globulin ) test measures the levels of TBG, one of the major transport proteins, which are primarily responsible for binding to and transporting thyroid hormones to the necessary tissues. TBG aids in assessing thyroid problems such as hypothyroidism or hyperthyroidism and also helps monitor ongoing treatment in patients with thyroid disorders. The T3 (Triiodothyronine) and T4 (Thyroxine) hormones bind to TBG protein. TBG has a greater affinity to thyroxine (T4). Abnormalities in the functionality and amount of TBG can cause variations in the total T4, but not in the amount of FreeT4. Since the amount of circulating free T4 remains the same, deficiency in TBG often does not lead to adverse metabolic effects seen in an individual with abnormal thyroid hormone levels. However, it can cause errors in the interpretation of thyroid hormones, which can lead to inappropriate treatment. The measurement of TBG can be used to establish the presence of TBG deficiency or excess suggested by abnormal Total serum T4 and T3 concentrations in the presence of normal free levels of these hormones.

Please note: This is an outsourced test. The sample for this test is collected by TATA 1MG and processed at a NABL accredited partnered lab.

Samples required

Blood

Find out

Why is this test booked?

Preparations

No special preparation is required.

Sample Collection

Who will collect your samples?

Frequently booked together

Anti-TPO Antibody (Anti-Thyroid Peroxidase Antibody)

~~₹1500~~

TSH Receptor Antibodies

~~₹4100~~

FAQs related to Thyroxine Binding Globulin in Varanasi

What additional tests can be performed in case the TBG results are not in the normal range?

If the TBG test results are not in the normal range, your doctor may ask for the following tests: Thyroid profile Free Anti Thyroperoxidase Antibody

Can medicines have any effect on the levels of TBG test?

Yes, certain medicines such as prednisone, phenothiazines, dilantin, depakene, depakote, drugs such as opioids and opiates or hormonal therapy such as estrogen therapy can affect the levels of TBG.

What is Hyperthyroidism?

Hyperthyroidism is a condition in which the thyroid gland is overactive and there is an increased production of thyroid hormones by the thyroid gland. Causes of Hyperthyroidism include Graves’ disease, multinodular goiter, thyroid nodules, toxic adenoma, inflammation of the thyroid, eating too much iodine, and too much synthetic thyroid hormone. Diagnosis of this condition can help to relieve the symptoms and prevent long-term complications.

What is Hypothyroidism?

Hypothyroidism, also called underactive thyroid or low thyroid is a condition in which the thyroid gland does not produce enough thyroid hormones. It can be commonly caused by intake of low iodine diet or Hashimoto's thyroiditis (an autoimmune disease). Less common causes include previous treatment with radioactive iodine, injury to the pituitary gland which secretes TSH, intake of certain medicines, previous thyroid surgery, or a lack of a functioning thyroid gland at birth.

Is there any risk associated with this test?

There is no risk associated with the test. However, since this test involves a needle prick to withdraw the blood sample, in very rare cases, a patient may experience increased bleeding, hematoma formation (blood collection under the skin), bruising or infection at the site of needle prick.

Content created by

Dr. Swati Gupta (Anand)

MD Lab Medicine, MBBS

Want to know moreRead our editorial policy

Last Updated

23rd Nov 2025