Urine C/S (Urine Culture and Sensitivity)
Understanding Urine C/S (Urine Culture and Sensitivity)
What is Urine C/S (Urine Culture and Sensitivity)?
The Urine C/S (Urine Culture and Sensitivity) test helps detect harmful bacteria and yeast (a few Candida spp.) in urine that may be causing a urinary tract infection (UTI). Additionally, the sensitivity test helps identify the antibiotics most effective against those particular bacteria. It is also used to determine if there is resistance to any antibiotics.
Urine is the body’s liquid waste made when the kidneys filter out toxins from the blood. It is made up of water, salt, electrolytes such as sodium and potassium, and some metabolic end products. The pathway followed by urine from the kidneys to the outside is called the urinary tract. Sometimes, the urinary tract may get infected by some microorganisms, causing a UTI.
The Urine C/S (Urine Culture and Sensitivity) test is usually done when you experience symptoms of UTI, such as:
- Burning sensation while passing urine
- Back pain
- Lower abdominal pain
- Urinating more often than usual
- Painful or frequent urination
- Blood in the urine, etc., for appx. 3-4 days and does not subside
This test helps identify infection-causing microorganisms. If the results are positive, the sensitivity test helps determine which drugs (or antibiotics) are likely to be most effective for treating the infection. On the other hand, a negative urine culture indicates no signs of microbial infection; hence, it will not show sensitivity to various antibiotics.
Before the test, avoid urinating for at least 4 hours before collecting the sample to ensure accurate results. Also, avoid drinking excessive fluids before collecting the urine sample, as it may dilute the urine and affect the results. The doctor may ask you to stop taking certain medications, like antibiotics and supplements, before a Urine C/S (Urine Culture and Sensitivity) test, as they may affect your test results. A midstream urine sample should be collected into a sterile container provided by the sample collection professional. Women are advised not to give the sample during the menstrual period unless prescribed, as that can interfere with certain test results.
Test result ranges are approximate and may differ slightly between different labs depending on the methodology and laboratory guidelines. Talk to your doctor about your specific test results. Narrate your complete medical history to help the doctor correlate your clinical and laboratory findings. The test results will help them determine your medical condition and formulate your overall treatment plan.
Lifestyle Tips to Prevent Urinary Tract Infection (UTI)
🥤Hydration: Keep it up! Stay hydrated to help flush out bacteria and reduce the likelihood of urinary tract infections (UTIs).
🥙Eat (Diet): Cranberry compounds may help prevent urinary tract infections (UTIs)
🚴Activity (Exercise): Pelvic floor exercises, also known as Kegel exercises, help strengthen the muscles that help empty the bladder.
Lifestyle (Hygiene): After urination or bowel movements, wipe from back to front to keep gut bacteria from getting into the urethra.
👨⚕️Talk to Your Doctor (Consult): If you have persistent UTI symptoms or are at high risk, consult your doctor about taking a urine culture test.
💊Habits (Antibiotics): Do not self-medicate. Your doctor may prescribe antibiotics to treat UTI.
What is Urine C/S (Urine Culture and Sensitivity) used for?
The Urine C/S (Urine Culture and Sensitivity) test can be done:
A. In Symptomatic Individuals
- Pain or burning while urinating
- Frequent urination
- Feeling the need to urinate despite having an empty bladder
- Bloody urine
- Pressure or cramping in the groin or lower abdomen
- Fever
- Chills
B. In Individuals With Risk Factors
- A previous UTI
- Recent sexual activity
C. In Individuals With Lifestyle-Related Risks
- Poor personal hygiene
D. In Special Populations
- Pregnancy
- Age (older adults and young children are more likely to get UTIs)
E. In Individuals With Anatomical Changes
- Structural problems in the urinary tract, such as an enlarged prostate
What does Urine C/S (Urine Culture and Sensitivity) measure?
The Urine C/S (Urine Culture and Sensitivity) test helps identify the bacteria or yeast (few candida spp.) causing UTI; the most common bacteria responsible for UTI is E.coli. Once the pathogen (harmful microorganism) is identified, the antibiotic susceptibility test is done to formulate a treatment plan for the infection.
Interpreting Urine C/S (Urine Culture and Sensitivity) results
Interpretations
Negative result: No colonies to less than 1,00,000 CFU/ml (Colony Forming Units)
Positive result:
· Usually more than 1,00,000 CFU/ml
· Patient undergoing antibiotic treatment: More than 1,000 CFU/ml
· For gram-positive bacteria like Staphylococcus aureus: Single colony
The negative result indicates no infection of the urinary tract.
The positive result indicates an infection of the urinary tract. An antibiotic susceptibility test accompanies the positive result.
Only a single colony type is found in an uncontaminated sample, indicating a clinically significant positive result. However, if multiple colonies of different types are found, sample contamination is indicated, and the sample may need to be collected again.
Answers to Patient Concerns & Frequently Asked Questions (FAQs) about Urine C/S (Urine Culture and Sensitivity)
Frequently Asked Questions about Urine C/S (Urine Culture and Sensitivity)
Q. What are the common UTI-causing microorganisms?
Q. What is a UTI?
Q. What is the difference between sensitive and resistant in urine culture?
Q. How is the Urine C/S (Urine Culture and Sensitivity) test different from the urine routine/microscopy (R/M) test?
Q. Can the Urine C/S (Urine Culture and Sensitivity) test detect sexually transmitted diseases?
Q. What can affect the results of the Urine C&S test?
Q. Can I have a negative urine culture test even with symptoms of UTI?
Q. What does “mixed growth” mean in culture?
Q. Can I have WBC/ pus cells in urine routine examination, but no organism on culture?
Q. What is the composition of urine?
Q. What is the normal pH of urine?
Q. What do pus cells in urine mean?
Q. What do yeast cells in urine indicate?
Q. What do crystals in urine indicate?
Q. What does the urine culture test cost?
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