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Uric Acid, Serum

Uric Acid, Serum

Also referred as
Uric acid
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The Uric Acid, Serum test measures the amount of uric acid present in your blood. This test is usually done as part of a kidney function test or as a routine blood test. It helps diagnose and monitor conditions related to abnormal uric acid levels, such as gout, kidney stones, and other kidney diseases. 

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Understanding Uric Acid, Serum

Uric acid is a nitrogenous waste product that forms when the body breaks down purines (substances found naturally in the body) and certain foods. Having a specific amount of uric acid level is normal and necessary for healthy bodily functions. But abnormal levels indicate various medical conditions. 

Uric acid levels are a key factor in the development of gout, a type of arthritis. The Uric Acid, Serum test aids in diagnosing gout and monitoring uric acid levels to prevent and manage gout attacks. Furthermore, uric acid is primarily excreted by the kidneys. Hence, this test is often used to evaluate kidney health, as abnormal uric acid levels may indicate impaired kidney function.

Doctors may recommend this test if you experience symptoms such as joint pain, swelling, and redness, which are key characteristics of gout. Furthermore, this test is also valuable if you experience symptoms such as severe lower back pain, nausea, and vomiting, associated with kidney stones. 

High uric acid levels in the blood is known as hyperuricemia. It can lead to gout, kidney disease, and certain cancers. Low levels (hypouricemia) can be seen in rare genetic disorders or liver disease. 

Usually, no special preparation is required for this test; eat and drink as per your daily routine. Inform the doctor about all the medications or supplements being taken as they might affect the test results.  

Test result ranges are approximate and may differ slightly between labs. Talk to the doctor about your specific test results. The results will help them determine your medical condition and formulate an overall treatment plan. They may suggest lifestyle recommendations and medications if required to manage your condition.

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What does Uric Acid, Serum measure?

The Uric Acid, Serum test measures the amount of uric acid in your blood. Uric acid is a waste product formed when the body breaks down purines. Purines are the natural substances found in your body’s cells (DNA) and in certain foods like red meat, or seafood. Under normal conditions, uric acid dissolves in the blood, passes through the kidneys, and is excreted in the urine. When this process doesn’t work properly, either due to increased production or reduced elimination, the uric acid can build up in the blood. This may indicate underlying health issues such as kidney dysfunction, gout, or presence of kidney stones. In some cases, the exact reason for high uric acid levels is unclear. On the other hand, low uric acid levels are rarely a cause for concern. This test helps doctors understand if uric acid levels are within a healthy range and whether further evaluation or treatment is needed.

FAQs related to Uric Acid, Serum

The Uric Acid, Serum test is used to detect gout and kidney stones by determining the levels of uric acid in your body.
Your doctor may advise the Uric Acid, Serum test when you experience symptoms like joint pain, redness, swelling, and shiny discoloration of the skin around the joints; severe lower back pain; nausea; and vomiting. This test is also used during radiotherapy and chemotherapy to measure uric acid levels.
No, this test is generally safe with minimal risks. However, you may feel slight discomfort during blood sample collection, but the chances of serious complications are extremely rare.
If your Uric Acid, Serum test results show higher levels, it might indicate conditions like gout, kidney stones, liver cirrhosis, obesity, malnutrition, hypothyroidism, and anemia. Whereas, if the test shows lower levels, it may indicate liver disease, Wilson's disease, or a syndrome of inappropriate antidiuretic hormone (SIADH).
Gout is a type of arthritis that causes sudden and severe joint pain. It usually affects only one or two joints simultaneously, typically in the feet and ankles. The common symptoms of gout are intense joint pain, redness, stiffness, swelling, and tenderness in joints.
The symptoms of kidney stones include severe pain on either side of the lower back, stomachache, blood in urine, nausea and vomiting, fever, and chills.
Hyperuricemia refers to a condition where the blood uric acid level is above the normal range. This condition may be caused due to an overproduction of uric acid or its improper elimination from blood.
Symptoms of hyperuricemia include inflammation, swelling, stiffness, pain in joints, pain in the lower back, abdomen, or sides, difficulty and pain during urination, blood in urine, etc.
Risk factors for hyperuricemia include kidney diseases, hypothyroidism or reduced secretion of hormones of the thyroid gland, hypertension or high blood pressure, hyperglycemia or high blood sugar, vigorous exercise of being extremely active physically, chronic exposure to lead metal, pesticide poisoning, obesity, alcoholism, and use of certain medications.
Gout is a condition that results in swelling of joints that is painful, most commonly in the lower limbs and toes. It occurs when there is excess uric acid in the blood that causes uric acid crystals to deposit in the joints. Pseudogout shares symptoms but is due to calcium pyrophosphate crystals, primarily in the knees, and occasionally the ankles, elbows, or wrists. It is associated with conditions such as elevated calcium or iron levels, thyroid disease, magnesium deficiency, or aging.
No, fasting is not required for this test. You can eat and drink as per your daily routine.
To manage uric acid levels, make sure you drink plenty of water throughout the day. Avoid alcohol and purine-containing foods such as red meat, organ meats, and some seafood. Consume low-fat dairy products, plant-based proteins, and fruit with high antioxidant content such as berries. Visit a doctor if elevated uric acid levels or symptoms of gout continue.
Content created by
Written by:
Dr. Lipika Khurana
PGDHHM, BDS
Reviewed by:
Dr. Anupriya Nautiyal
MD Pathology, MBBS
Want to know moreRead our editorial policy
Last Updated6th Oct 2025

Uric Acid, Serum test price for other cities

Price inKolkataRs. 139
Price inBangaloreRs. 179
Price inNew DelhiRs. 159
Price inMumbaiRs. 179
Price inGurgaonRs. 159

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Contains 1 test
Uric Acid, Serum