RBC Folate
Understanding RBC Folate
What is RBC Folate?
The RBC Folate is a blood test that measures stored folate (vitamin B9) in red blood cells (RBCs), assessing the body's long-term folate status. It helps detect suspected deficiency states and distinguishes folate-related anemia from other types, like B12 deficiency.
Red blood cell (RBC) folate reflects the body's folate stores over the 120-day lifespan of RBCs, unlike serum folate, which only shows recent intake. Folate plays a critical role in DNA synthesis, red blood cell production, cellular division, and fetal development during pregnancy.
A folate deficiency can lead to various health complications, including anemia, where the body lacks enough red blood cells to carry oxygen to its tissues. Maintaining adequate folate levels is essential for preventing anemia and supporting overall health.
The RBC Folate test can be done when there are symptoms such as fatigue, weakness, pale skin, shortness of breath, and difficulty concentrating, all suggestive of anemia. This test is especially critical for pregnant women to ensure adequate folate levels for proper fetal brain and spinal cord development, helping prevent neural tube defects like spina bifida. It's also used to monitor treatment effectiveness in folate deficiency anemia, assess individuals with nutrient absorption disorders (such as celiac disease or Crohn's), and evaluate those taking medications known to interfere with folate metabolism.
No special preparation is needed for getting the RBC Folate test done. However, be sure to inform the doctor about any medications or supplements being taken, as they may affect the test results. Also, avoid taking biotin for at least 8 hours before giving the blood sample.
Lab test results may vary across different laboratories. Abnormal test results require expert interpretation. Therefore, never try to self-medicate based solely on these results. Always consult a doctor for a proper understanding of the test results.
Please note: This is an outsourced test. The sample for this test is collected by TATA 1MG and processed at a NABL accredited partnered lab.
What is RBC Folate used for?
The RBC Folate test is done:
- To diagnose folate deficiency anemia, which occurs when the body does not have enough folate.
- To monitor the folate levels in pregnant women to prevent birth defects.
- To monitor the response to treatment in individuals with other medical conditions that affect folate levels.
What does RBC Folate measure?
The RBC Folate test measures the amount of folate inside red blood cells. Since folate is stored within RBCs for several months, this test provides a more accurate reflection of the body’s long-term folate status than serum folate tests, which can be affected by recent folate intake. Low RBC folate levels suggest a chronic folate deficiency, which can impair DNA synthesis, hinder red blood cell development, and contribute to cognitive and developmental disorders.
Interpreting RBC Folate results
Interpretations
Normal test results determine that there is no vitamin deficiency. Also normal levels can indicate that the stored vitamin level has not yet been exhausted.
Frequently Asked Questions about RBC Folate
Q. What is the RBC Folate test?
Q. Why do I need this test?
Q. What is the difference between RBC Folate and serum folate tests?
Q. Do I need to fast before the test?
Q. How is the test done?
Q. Are there any risks with this test?
Q. How do I prepare for the test?
Q. What do the test results mean?
Q. What happens if my folate level is low?
Q. What is the difference between folate and folic acid?
Q. Why is RBC folate important during pregnancy?
Q. How does Tata 1mg ensure accurate lab test results?
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