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Quadruple Marker with Graph - 2nd Trimester

Quadruple Marker with Graph - 2nd Trimester near me in Pune

Also referred as
Quadruple marker test
Quad marker screening
421+ booked recently
For women
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108 hours
Contains
4 tests
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A Quadruple Marker with Graph - 2nd Trimester is a prenatal screening test typically conducted between the 14th and 22nd weeks (ideal 15-20 weeks, i.e., second trimester) of pregnancy. It tells about the risk of specific chromosomal abnormalities, such as Down syndrome (Trisomy 21), Edwards Syndrome (Trisomy 18), neural tube defects (such as spina bifida), and anencephaly (a brain defect) in the fetus. It is widely available with Tata 1mg labs at an affordable price in Pune. 

This test measures the levels of four specific biomarkers in the mother’s blood: Alpha-fetoprotein (AFP), Human Chorionic Gonadotropin (hCG), Estriol unconjugated (uE3), and Inhibin A. The levels of these markers, when assessed collectively along with maternal age, gestational age, and ultrasound findings, help determine the likelihood of certain fetal abnormalities that can affect the baby’s growth and development. 

In addition to the traditional Quad marker analysis, the inclusion of a graphical representation enhances the interpretability of results.  

No special preparation is required before undergoing a Quadruple Marker with Graph - 2nd Trimester test. However, a woman needs to provide informed consent before undertaking this test. The laboratory personnel will explain the purpose, benefits, and limitations of this test.

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Understanding Quadruple Marker with Graph - 2nd Trimester

A Quadruple Marker with Graph - 2nd Trimester test is a prenatal screening test tailored to provide expectant parents with insights into the developing baby's health. It analyzes specific markers in the mother’s blood to assess the risk of chromosomal abnormalities, such as Down Syndrome (Trisomy 21) and Edwards Syndrome (Trisomy 18), wherein extra copies of chromosome 21 and 18 are present and affect the baby's physical and intellectual development. It also screens for neural tube defects like spina bifida (a spinal cord defect) and anencephaly (a brain defect). These birth defects can result in nerve damage, learning disabilities, paralysis, or stillbirth.

The Quad in Quadruple Marker with Graph - 2nd Trimester test refers to the four specific markers measured in the mother’s blood during the screening. These include Alpha-fetoprotein (AFP), Human Chorionic Gonadotropin (hCG), Estriol unconjugated (uE3), and Inhibin A. When assessed collectively, the levels of these markers help estimate the likelihood of certain fetal abnormalities that can affect the baby’s growth and development. Timely detection of these abnormalities is vital for ensuring comprehensive prenatal care and effectively addressing potential health problems. In addition to the traditional Quad marker analysis, the inclusion of a graphical representation enhances the interpretability of results. 

A Quadruple Marker with Graph - 2nd Trimester test is a screening test only; any abnormal result does not mean the unborn baby has a birth defect or genetic condition. It only tells whether the unborn baby is at risk of developing certain abnormalities, and further testing is required to confirm the diagnosis.

The recommendation of a Quadruple Marker with Graph - 2nd Trimester test is often based on maternal age, medical history, and individual risk factors for chromosomal abnormalities. Pregnant women should consult their doctor to determine the most appropriate screening or diagnostic test based on their specific circumstances. 

No special preparation is required before undergoing a Quadruple Marker with Graph - 2nd Trimester test. However, a woman needs to be prepared to provide informed consent before undertaking this test. The laboratory personnel will explain the purpose, benefits, and limitations of this test.

Abnormal lab test results represent only the risk but not the diagnostic outcomes. Increased risk does not mean the baby is affected; further tests must be performed before a confirmed diagnosis can be made. Talk to your doctor about your specific test results. 

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What does Quadruple Marker with Graph - 2nd Trimester measure?

Contains 4 tests

A Quadruple Marker with Graph - 2nd Trimester test measures the levels of four specific markers in a pregnant woman's blood. These markers are -Alpha-Fetoprotein (AFP), Human Chorionic Gonadotropin (hCG), Estriol Unconjugated , and  Inhibin-A.

The analysis of these four markers and other factors like maternal age and gestational age helps assess the risk of certain conditions in the developing baby. The graph in a Quadruple Marker with Graph - 2nd Trimester provides a visual representation of the levels of these markers during pregnancy. 

It is noteworthy that a Quadruple Marker with Graph - 2nd Trimester is a screening test, and any abnormal results may prompt further diagnostic testing for confirmation. Pregnant women should discuss their results and implications with their doctor.

The Inhibin A test measures the level of inhibin A in the blood. It is a hormone primarily produced by the ovaries in women. It plays a key role in regulating menstrual cycle and ovarian function by inhibiting the production of follicle-stimulating hormone (FSH). During pregnancy, elevated levels of Inhibin A may point towards a risk of certain chromosomal abnormalities like Down’s syndrome etc., in the fetus. 

The Inhibin A test is particularly useful in assessing ovarian function, fertility assessment, prenatal screening and diagnosing certain ovarian cancers.

Know more about Inhibin A

The HCG Beta Total Quantitative, Maternal test measures the levels of human chorionic gonadotropin (hCG) hormone in the blood. hCG is released in the blood during pregnancy and can be detected as early as 10 to 12 days after conception. The levels of this hormone gradually rise every 2 to 3 days (or 48 to 72 hours) and peak around 8 to 11 weeks after conception. After reaching the peak, the hCG levels decrease and remain steady for the rest of the pregnancy.

Know more about HCG Beta Total Quantitative, Maternal

An Alpha Feto Protein, Maternal test measures the amount of Alpha Fetoprotein in expectant mothers usually during the second trimester (14th and 22nd weeks). AFP is a protein produced by the fetus, primarily by the fetal liver and yolk sac, and it passes into the mother's blood. The test is typically performed to screen for certain fetal abnormalities, particularly neural tube defects (NTDs) such as spina bifida and anencephaly, as well as chromosomal abnormalities like Down syndrome (trisomy 21), Edwards syndrome (Trisomy 18), etc. 

Detecting these abnormalities early in pregnancy allows for appropriate medical management and intervention.

Know more about Alpha Feto Protein, Maternal

The Estriol Unconjugated test is used to assess the level of unconjugated estriol (uE3) in the blood, a specific type of estrogen produced during the pregnancy phase. This hormone is mainly synthesized in the placenta and the fetus, with the fetus being responsible for a substantial amount of uE3 production as it grows. 

Monitoring the uE3 levels in the maternal serum is useful in evaluating the condition of the fetus. Abnormal unconjugated estriol levels may indicate pregnancy-related complications or concerns, including chromosomal abnormalities, fetal distress, or placental problems. The Estriol Unconjugated is particularly crucial in the second trimester to assess for some conditions, such as Down syndrome, Edward syndrome, or other chromosomal abnormalities, fetal growth and development. Hence the estriol unconjugated test is a significant part of prenatal care as it reveals information that may be valuable for the diagnosis and management of the mother and the baby.

Know more about Estriol Unconjugated

FAQs related to Quadruple Marker with Graph - 2nd Trimester in Pune

A Quadruple Marker with Graph - 2nd Trimester is a prenatal screening test that evaluates the risk of chromosomal abnormalities and neural tube defects in the developing baby, helping in early detection and appropriate management.
A quad marker test assesses four specific biomarkers: AFP (alpha-fetoprotein), HCG (human chorionic gonadotropin), Estriol unconjugated (a form of estrogen), and Inhibin-A.
You can undergo a quad marker test in the second trimester i.e., between weeks 15 and 22 of pregnancy.
The test involves a simple and safe blood draw from the pregnant woman, posing no risk to the developing baby. It is a non-invasive screening test.
A quad marker test primarily screens for Down syndrome (Trisomy 21) and Edwards’ syndrome (Trisomy 18).
Yes, Tata 1mg Labs offers a quad marker test in Pune near you. The test is easy to book, is pocket-friendly, and comes with a comprehensible report.
Yes, home sample collection for a quad marker test is readily available in Pune. Tata 1mg Labs allows you to choose a date and time that suits your schedule for sample collection.
If you want to schedule a quad marker test with Tata 1mg Labs in Pune, the procedure is fairly easy and hassle-free. Follow these steps to book a test: 1). Visit the Lab Tests section on the Tata 1mg website. 2). Add the test you want in the cart. 3). Pick a time and date slot according to your convenience; however, do consider the necessary prerequisites while scheduling a test. 4). You will receive a notification with all the details once the test is scheduled.
Tata 1mg Labs is a pocket-friendly platform for booking lab tests in Pune. A quad marker test is available at an affordable price of Rs. 2879.
The e-report of your quad marker test can be found on the Tata 1mg app in downloadable PDF form. This allows you to access your test results at convenience and securely share them with your healthcare provider for further consultation and guidance regarding your overall health. You can also opt for a hard copy of the reports at a minimal price. Tata 1mg Labs is a pocket-friendly platform for booking lab tests in Pune. A Quadruple Marker with Graph - 2nd Trimester test is available at an affordable price of Rs. 2879.
At Tata 1mg Labs, we understand the importance of timely results. We strive to provide fast turnaround times for test results, allowing you to get the information you need promptly. On average, we take 108 hours to provide the reports of a quad marker test in Pune.
Content created by
Written by:
Dr. Lipika Khurana
PGDHHM, BDS
Reviewed by:
Dr. Swati Gupta (Anand)
MD Lab Medicine, MBBS
Want to know moreRead our editorial policy
Last Updated5th Oct 2025

Quadruple Marker with Graph - 2nd Trimester test price for other cities

Price inNew DelhiRs. 3239
Price inGurgaonRs. 3239
Price inBangaloreRs. 3019
Price inMumbaiRs. 2969
Price inGhaziabadRs. 2850

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Contains 4 tests
Inhibin A
HCG Beta Total Quantitative, Maternal
Alpha Feto Protein, Maternal
Estriol Unconjugated