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Immunoglobulin Profile

Also referred as

Immunoglobulins (IgA

IgG

IgM)

Immunoglobulins Blood Test

157+ booked recently

For men & women

Earliest reports in

48 hours

Contains

3 tests

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The Immunoglobulin Profile measures the level of immunoglobulins (antibodies) A, G, and M (IgA, IgG, and IgM) in the blood. It helps assess the functioning of the immune system and diagnose conditions like immunodeficiency, etc. that affect the immunoglobulin levels.

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Blood

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Understanding Immunoglobulin Profile

Immunoglobulins are the proteins that are produced by the immune system to fight off harmful substances. The Immunoglobulin Profile evaluates three primary types of immunoglobulins: IgA, IgG, and IgM. IgA antibodies are the second most abundant antibodies that are produced by the immune system against microbial infections and help maintain immune homeostasis. IgG antibodies are the most abundant antibodies. They provide long-term immunity against infections. IgM antibodies are the first antibodies produced by the immune system against foreign invaders (antigens).

The Immunoglobulin Profile test helps evaluate the competency and functioning of the immune system. It aids in diagnosing immunodeficiency disorders (e.g., primary immunodeficiency, Human Immunodeficiency Virus (HIV), etc.). It also helps identify autoimmune conditions (e.g., rheumatoid arthritis (RA), etc.) and monitors treatment response and infection status in the body.

The Immunoglobulin Profile is recommended for individuals with recurrent infections. It is also advised for those with chronic diseases, autoimmune disorders, or unexplained symptoms.

No special preparation is required for this profile. Inform the doctor about all medications or supplements being taken, as well as a history of chronic illnesses or vaccinations, as these may affect the test results.

Lab test results may vary across laboratories. Interpretation of the test results requires professional expertise. Do not self-medicate solely based on these test results, and consult your doctor to understand your test results correctly.

What does Immunoglobulin Profile measure?

Contains 3 tests

The Immunoglobulin Profile measures the levels of three primary classes of immunoglobulins: immunoglobulin A (IgA), immunoglobulin M (IgM), and immunoglobulin G (IgG), which play crucial roles in the body’s immune response. IgA is found mainly in mucous membranes and protects against infections at mucosal surfaces, like the respiratory and gastrointestinal tracts. IgM is the first antibody produced in response to an infection and provides initial immune defense. IgG, the most abundant antibody in the bloodstream, provides long-term immunity and helps protect against bacterial and viral infections. This profile helps diagnose immune deficiencies, autoimmune diseases, and chronic infections. Additionally, it monitors the immune system’s overall health.

Immunoglobulin A

The Immunoglobulin A test measures the concentration of IgA antibodies in the blood. The immune system produces these antibodies in response to pathogens and is primarily active in the mucosal membranes of the body, where they help prevent infections. Elevated levels of IgA may indicate chronic infections, autoimmune conditions, or inflammation, while lower levels can suggest immunodeficiency or impaired antibody production. This test provides essential insight into an individual’s mucosal immune health and is important for diagnosing and managing immune-related conditions.

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Immunoglobulin G

The Immunoglobulin G test measures the concentration of IgG antibodies present in the serum. These antibodies are produced by the immune system in response to specific pathogens or infections. Elevated levels of IgG can indicate recent or chronic infections, while lower levels may suggest an impaired immune response or deficiency. This test is crucial for assessing an individual’s immune status and provides valuable information for doctors to make informed clinical decisions regarding diagnosis, treatment strategies, and ongoing management of various health conditions.

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Immunoglobulin M

The Immunoglobulin M test measures the concentration of IgM antibodies in the blood. These antibodies are typically the first line of defense produced by the immune system during an initial exposure to a pathogen (bacteria, virus, etc). Elevated IgM levels indicate a recent or ongoing infection, while low or absent IgM levels suggest that an individual is either not currently infected or that the immune system has entered a later phase of response. This test is particularly useful for diagnosing acute infections and for distinguishing between new and past infections.

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FAQs related to Immunoglobulin Profile in Cuttack

What is the Immunoglobulin Profile?

The Immunoglobulin Profile is a blood test that measures the levels of three major antibodies: immunoglobulin A (IgA), immunoglobulin M (IgM), and immunoglobulin G (IgG). These antibodies are vital components of the immune system. They help diagnose various immune deficiencies, autoimmune diseases, and chronic infections.

Why would my doctor order this test?

Your doctor may recommend this test if you have frequent or severe infections, symptoms of an autoimmune disease, or if they suspect an immune deficiency. It can also help monitor the effectiveness of treatment for immune-related conditions.

Do I need to fast before taking the Immunoglobulin Profile?

No, fasting is not required for the Immunoglobulin Profile. However, it’s best to inform your doctor about any medications or supplements you are taking, as these may influence the results.

What do high or low levels of immunoglobulins indicate?

High levels of IgA, IgM, or IgG may indicate infections, autoimmune diseases, chronic inflammatory conditions, or certain malignancies. Low levels could suggest an immune deficiency, risk of infections, or immune suppression. Your doctor will interpret these results in the context of your overall health and medical history.

Are there any risks associated with this test?

No, the Immunoglobulin Profile is generally safe with minimal risks. However, you may feel slight discomfort during blood sample collection, but chances of serious complications are extremely rare.

Can I take this test during an ongoing infection or illness?

Yes, you can take this test during an active infection or illness, as it can provide valuable insights into your immune system’s response. However, always consult with your healthcare provider to determine the appropriate timing for testing.

Can I take this test during an ongoing infection or illness?

What is immunoglobulin G (IgG), and why is it important?

IgG is the most common antibody in the blood and plays a vital role in protecting the body from infections by remembering past pathogens and providing long-term immunity. It is also the only antibody that can cross the placenta to protect a developing fetus.

What is immunoglobulin A (IgA), and what role does it play?

IgA is found in mucous membranes, such as those lining the respiratory and gastrointestinal tracts, as well as in saliva, tears, and breast milk. It provides localized protection against infections.

What is immunoglobulin M (IgM), and why is it significant?

IgM is the first antibody the body produces when fighting an infection. It provides early immune response and helps to activate other immune functions.

Can IgG, IgA, or IgM levels change over time?

Yes, immunoglobulin levels can change due to infections, autoimmune conditions, or other health issues. Antibody levels may fluctuate as your immune system responds to or recovers from illnesses, and they can also be influenced by treatments or medications.

Can vaccinations influence IgG, IgA, or IgM levels?

Yes, vaccinations are designed to stimulate the immune system to produce IgG antibodies against specific pathogens. This provides long-term protection and immunity. In some cases, vaccines may also stimulate IgA production, especially if the vaccine is administered through mucosal routes like nasal sprays. IgM is usually not a target of vaccines, as it is associated with the early response to infections.

How does Tata 1mg ensure accurate lab test results?

Tata 1mg ensures accurate lab test results through certified laboratories that use advanced technology and adhere to stringent quality control measures. This commitment to high standards guarantees reliable results.

Content created by

Dr. Swati Gupta (Anand)

MBBS, MD Lab Medicine

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Last Updated

6th Oct 2025