
HLA - B27 Detection by Flowcytometry near me in Gautam Buddha Nagar









An HLA - B27 Detection by Flowcytometry is a blood test that helps to identify the presence of Human Leukocyte Antigen B27(HLA B-27), a specific type of protein present on the surface of white blood cells (WBCs) that helps the body's immune system tell the difference between its own cells and foreign/harmful substances and helps diagnose autoimmune disorders. This test is widely available at an affordable price in Gautam Buddha Nagar.
Your doctor may suggest an HLA B-27 test if you experience signs and symptoms such as stiffness and chronic pain in the back, neck, or chest, inflammation in eyes, urethra, and joints, the appearance of skin lesions, recurring fever, abdominal pain, or digestive problems indicative of an autoimmune disorder. Additionally, this test is also used during an organ transplant to match donated tissue with the recipient to minimize the risk of organ rejection and improve the success of the transplantation.
No special preparation is needed for this test. You may eat and drink as per your daily routine.








What does HLA - B27 Detection by Flowcytometry measure?
An HLA - B27 Detection by Flowcytometry test evaluates the presence or absence of HLA B27 antigen to rule out the possibility of any autoimmune disorder. Once recognizing any cell as foreign and dangerous, the human leukocyte antigens (HLA) set out to destroy those cells to protect the body from any harm. The majority of the HLAs protect the body from damage, however, HLA-B27 is a specific type of protein that contributes to the dysfunction of the body’s immune system. The presence of HLA-B27 on the white blood cells can cause the immune system to attack those otherwise healthy cells. When this occurs, it can result in an autoimmune disease.





FAQs related to HLA - B27 Detection by Flowcytometry in Gautam Buddha Nagar
- Parameswaran P, Lucke M. HLA-B27 Syndromes. [Updated 2023 Jul 4]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from:
- Zochling J, Bohl-Bühler MH, Baraliakos X, Feldtkeller E, Braun J. Infection and work stress are potential triggers of ankylosing spondylitis. Clin Rheumatol. 2006 Sep;25(5):660-6.[Accessed 06 Nov. 2023]. Available from:
- HLA- B27 Antigen [Internet]. Rochester, NY: University of Rochester Medical Center; [Accessed 28 Nov. 2023]. Available from:
- N P, Shanmugam SG, Devi SS, Chinambedu Dandapani MP, S R, D'Cruze L. Detection of Human Leukocyte Antigen B27 by Flowcytometry in Patients With Suspected Ankylosing Spondylitis in a Tertiary Care Centre. Cureus. 2021 Feb 25;13(2):e13560. [Accessed 28 Nov. 2023]. Available from:
- McMichael A, Bowness P. HLA-B27: natural function and pathogenic role in spondyloarthritis. Arthritis Res. 2002;4 Suppl 3(Suppl 3):S153-8. [Accessed 28 Nov. 2023]. Available from:
- Ankylosing Spondylitis. [Internet]. NIH; May. 2023. [Accessed 28 Nov. 2023]. Available from:
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