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Glucose Challenge Test 50g (Glucose 1 Hour Obstretical)

Also referred as

50-g GLT (Non-fasting)

Glucose load test

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For women

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The Glucose Challenge Test 50g (Glucose 1 Hour Obstretical) is a preliminary blood screening test done during pregnancy (usually between 24 and 28 weeks) to assess the risk of developing gestational diabetes mellitus (GDM). The test involves drinking a 50g glucose solution and measuring blood sugar levels one hour later to determine if they fall within a normal range.

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Understanding Glucose Challenge Test 50g (Glucose 1 Hour Obstretical)

The Glucose Challenge Test 50g (Glucose 1 Hour Obstretical) checks for gestational diabetes mellitus (GDM), a condition characterized by impaired glucose tolerance that emerges during pregnancy. This condition can pose significant health risks to both the mother and the developing baby, including complications during labor and long-term metabolic issues.

The Glucose Challenge Test 50g (Glucose 1 Hour Obstretical) is typically recommended during the second trimester of pregnancy. However, it can be done earlier if there are risk factors such as a body mass index (BMI) of 30 or higher, a lack of physical activity, a medical condition linked to getting diabetes, such as metabolic syndrome or polycystic ovary syndrome (PCOS), being 35 or older during pregnancy, etc. This one-hour test helps identify any abnormal glucose metabolism early, allowing for timely intervention and management of GDM. Detecting and managing gestational diabetes is important to prevent complications such as high birth weight babies, preterm birth, and the development of type 2 diabetes in the future for both the mother and the child.

For this test, the patient should drink a solution containing 50g of glucose anhydrous (equivalent to 55g of glucose monohydrate) dissolved in 250-300 mL of cold water and consume it orally over a 5-minute period. The blood sample should then be collected 1 hour after the glucose test load intake. All pregnant women, previously known to have no diabetes should be evaluated for gestational diabetes mellitus (GDM) at 24 to 28 weeks of gestation. Additionally, the doctor should be informed if vomiting occurs during the 1-hour period after glucose consumption.

Test results may vary across laboratories based on the methodology and laboratory guidelines. Do not self-medicate at home solely based on these results. Always consult the doctor for a proper understanding of the test results. The test results will help the doctor decide whether to recommend dietary modifications, lifestyle changes, or medications necessary to manage the condition.

NOTE: Parameters covered - 1 (Glucose challenge at 1 hour)

What does Glucose Challenge Test 50g (Glucose 1 Hour Obstretical) measure?

The Glucose Challenge Test 50g (Glucose 1 Hour Obstretical) measures how well your body processes or utilizes sugar (glucose), particularly during pregnancy. It is specifically tailored to screen for gestational diabetes mellitus (GDM), a condition where blood sugar levels are elevated during pregnancy. By drinking a solution containing a specific amount of glucose and then having blood sugar levels measured afterward, doctors can assess how effectively your body tolerates glucose. This test helps detect any abnormalities in glucose metabolism early, allowing for timely management to ensure a healthy pregnancy for both the mother and the baby.

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FAQs related to Glucose Challenge Test 50g (Glucose 1 Hour Obstretical)

What is the Glucose Challenge Test 50g (Glucose 1 Hour Obstretical)?

The Glucose Challenge Test 50g (Glucose 1 Hour Obstretical) is a screening test done during pregnancy to check for gestational diabetes mellitus (GDM). It involves drinking a specific amount of oral glucose solution and then measuring the blood sugar levels after 1 hour of administration to see how the body processes the sugar.

When should I take my Glucose Challenge Test 50g (Glucose 1 Hour Obstretical)?

People at average risk of gestational diabetes usually have this test done during the second trimester, generally between 24 and 28 weeks of pregnancy. However, it can be done earlier if risk factors are present.

Is fasting required before the Glucose Challenge Test 50g (Glucose 1 Hour Obstretical)?

No, fasting is not mandatory. This test can be done at any time of the day, regardless of whether you have eaten recently.

Is there any risk associated with the Glucose Challenge Test 50g (Glucose 1 Hour Obstretical)?

No, there is no risk associated with the Glucose Challenge Test 50g (Glucose 1 Hour Obstretical). It is a safe procedure. It generally involves a blood sample withdrawal from the vein of the arm. However, some individuals may experience bruising or swelling at the needle prick site, which is usually self-limiting and not bothersome.

Is there any specific time of day that's best for the test?

There is no specific best time for the test. It can be done at your convenience during regular clinic hours, but it’s best to follow your doctor’s guidance.

What if I vomit after drinking the glucose solution?

If you vomit, you should inform your healthcare advisor right away. They may recommend rescheduling the test to ensure accurate results.

Will this test affect my baby?

The Glucose Challenge Test is safe and poses no risk to your baby. It is tailored to help ensure a healthy pregnancy and reduce the risk of complications for both mother and child.

What do the abnormal test results mean?

Abnormal results may indicate gestational diabetes, which will require further testing and treatment to manage blood sugar levels during pregnancy. Consult your doctor for a proper understanding of the test results.

How does Tata 1mg ensure accurate lab test results?

Tata 1mg ensures accurate lab test results through certified laboratories that use advanced technology and adhere to stringent quality control measures. This commitment to high standards guarantees reliable results.

Content created by

Dr. Swati Gupta (Anand)

MBBS, MD Lab Medicine

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Last Updated

13th Oct 2025