CMV (Cytomegalovirus) Avidity near me in Chennai

The CMV (Cytomegalovirus) Avidity test measures the binding strength (avidity) of CMV-specific IgG antibodies in the blood. When a person is newly infected with CMV, the IgG antibodies produced are of low avidity, meaning they bind weakly to the virus. This low avidity usually indicates a recent primary infection within the last 3–4 months. Over time, as the immune response matures, the IgG antibodies gain high avidity, binding more strongly to the virus, which reflects a past infection or established immunity due to earlier exposure or vaccination. By distinguishing between recent and past infections, this test provides crucial insights for clinical decision-making. It is especially useful in high-risk groups such as pregnant women, where a recent infection may affect the fetus. It is also important for individuals with weakened immune systems, where CMV reactivation can lead to serious complications.