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Beta 2 Glycoprotein 1, IgA

Beta 2 Glycoprotein 1, IgA

Also referred as
Anti-Beta-2-Glycoprotein 1 IgA Test
Beta-2-GP1 IgA Test
Anti-B2GP1 IgA Serum
For men & women
Earliest reports in
192-216 hours
Contains
1 test
Know more about this test

The Beta 2 Glycoprotein 1, IgA is a blood test that helps detect the presence of immunoglobulin A (IgA) antibodies targeting Beta 2 Glycoprotein 1 (β2GPI), a protein found in abundance in the blood plasma. These antibodies are often linked to autoimmune conditions like antiphospholipid syndrome (APS), where they can contribute to an increased risk of blood clots, miscarriage, and other health complications.

 

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Understanding Beta 2 Glycoprotein 1, IgA

Beta 2 Glycoprotein 1 (β2GPI) is a protein that regulates blood clotting. In APS, the immune system mistakenly produces anti-β2GPI antibodies, leading to abnormal clot formation. These clots can cause serious complications like deep vein thrombosis (DVT), pulmonary embolism (PE), stroke, heart attack, and recurrent miscarriages.

This test is often recommended for individuals who have unexplained blood clots, repeated pregnancy losses, and other pregnancy complications related to blood clotting, or signs of antiphospholipid syndrome (APS), like strokes or miscarriages. It is also helpful for checking how well treatment is working in individuals with APS or autoimmune diseases like lupus (SLE), which can have similar antibodies. This test can help detect APS early, even if standard IgG and IgM tests are negative.

No special preparation is needed before the Beta 2 Glycoprotein 1, IgA test. However, inform the doctor about all the medications or supplements being taken, as a few of them may affect the test results, potentially requiring dosage adjustments or temporary discontinuation before the test.

Lab test results may vary across different laboratories. Abnormal test results require an expert interpretation. Therefore, never try to self-medicate at home based solely on these results. Always consult a doctor for a proper understanding of the test results. The insights from this test help the doctor tailor an appropriate treatment plan.

Please note: This is an outsourced test. The sample for this test is collected by TATA 1MG and processed at a NABL accredited partnered lab.

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What does Beta 2 Glycoprotein 1, IgA measure?

The Beta 2 Glycoprotein 1, IgA test checks for the presence of immunoglobulin A (IgA) antibodies against beta 2 glycoprotein 1, a protein that helps regulate blood clotting. IgA is an antibody mostly found in mucosal areas like the gut and respiratory tract, but in autoimmune conditions, it can appear in the blood and target the body’s own tissues.

Elevated levels of these IgA antibodies can indicate an active autoimmune response. In the context of pregnancy, high levels may be associated with poor outcomes, such as recurrent miscarriages. This test is particularly useful if the initial antiphospholipid antibody tests for the IgG and IgM classes are negative but APS is still strongly suspected.

FAQs related to Beta 2 Glycoprotein 1, IgA

The Beta 2 Glycoprotein 1, IgA test checks for IgA antibodies against a protein called beta 2 glycoprotein 1, which plays a role in blood clotting. These antibodies may be present in certain autoimmune conditions, such as antiphospholipid syndrome (APS).
Your doctor may recommend this test if you have unexplained blood clots, recurrent miscarriages, or other symptoms that could be related to antiphospholipid syndrome (APS). It helps assess the risk of clotting disorders, especially when there is a history of deep vein thrombosis (DVT), pulmonary embolism (PE), stroke, or other thrombotic events.
No, fasting is not required for the Beta 2 Glycoprotein 1, IgA test. You can eat and drink as usual before the test unless your doctor instructs otherwise.
A phlebotomist (a trained professional to perform blood draws) will clean your skin using an antiseptic alcohol cotton swab or wipe and take blood samples from your vein using a needle. The blood sample will be stored safely and transported to the laboratory for analysis.
While IgG and IgM tests are commonly used to detect APS, the IgA test is useful when IgG and IgM are negative, but symptoms strongly suggest APS. It can provide additional clues in complex cases.
A positive result means higher levels of beta-2-glycoprotein 1 IgA antibodies, which may indicate antiphospholipid syndrome (APS).
A negative result means that beta-2-glycoprotein 1 IgA antibodies were not detected. This makes antiphospholipid syndrome (APS) less likely, but your doctor will consider symptoms and other tests to make a complete assessment.
Yes, this test is safe during pregnancy. In fact, it is often recommended when a woman has had recurrent miscarriages or pregnancy complications possibly linked to APS or clotting issues.
Yes. It is often done alongside beta 2 glycoprotein IgG and IgM antibody tests, lupus anticoagulant tests, and other autoimmune tests to get a full understanding of APS.
Tata 1mg ensures accurate lab test results through certified laboratories that use advanced technology and adhere to stringent quality control measures. This commitment to high standards guarantees reliable results.
Content created by
Written by:
Shweta Prakash
MSc, BSc
Reviewed by:
Dr. K Madhuri Reddy
MD Pathology, MBBS
Want to know moreRead our editorial policy
Last Updated14th Dec 2025

Beta 2 Glycoprotein 1, IgA test price for other cities

Price inBangaloreRs. 1169
Price inNew DelhiRs. 899
Price inMumbaiRs. 1249
Price inGhaziabadRs. 950
Price inGautam Buddha NagarRs. 950

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Contains 1 test
Beta 2 Glycoprotein 1, IgA