Anti - Neutrophil Cytoplasmic Antibodies (ANCA) by IFA near me in Kamrup

Anti-neutrophil cytoplasmic antibodies (ANCA) are antibodies that the body’s immune system makes by mistake. They target neutrophils, a type of white blood cell. In conditions like vasculitis, ANCA causes these neutrophils to attack the blood vessels, leading to inflammation and damage. This can affect important organs like the kidneys, lungs, and sinuses, causing serious symptoms.

The Anti - Neutrophil Cytoplasmic Antibodies (ANCA) by IFA test is a group of blood tests. It is tailored to detect specific ANCA antibodies in the blood. It looks for three main types of ANCA: MPO (p-ANCA), PR3 (c-ANCA), and atypical ANCA. These markers are crucial in identifying different forms of ANCA-associated vasculitis (AAV), such as granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA).

The Anti - Neutrophil Cytoplasmic Antibodies (ANCA) by IFA test is done when a doctor suspects autoimmune vasculitis symptoms such as persistent fever, weight loss, fatigue, joint pain, skin rash, or unexplained inflammation. It may also be done if someone has a family history of autoimmune diseases. It is also beneficial for someone who already has autoimmune conditions, such as inflammatory bowel disease. 

A positive result means that ANCA antibodies are present in the blood. This suggests the possibility of vasculitis. The specific type of ANCA found helps identify the type of vasculitis, guiding treatment. A negative result generally indicates that ANCA-associated vasculitis is unlikely. However, it doesn't completely rule out the condition, as some forms of vasculitis may not involve ANCA antibodies. Additional testing is recommended to establish a comprehensive diagnosis following discussion with your clinician.

Usually, no special preparation such as fasting or dietary restriction is needed for this test.  Inform the doctor about all the medicines and supplements being taken, as some of them may affect the test results.  

Test result ranges may vary across laboratories. Abnormal test results require an expert interpretation. Therefore, never try to self-medicate at home based solely on these results. Always consult a doctor for a proper understanding of the test results.