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Anti - dsDNA Antibody (Double Stranded, Native) by IFA

Also known as Anti-dsDNA Antibody Test, Anti-double stranded DNA Antibody Test

₹2249~~₹3900~~ 42% Off

You need to provide

Blood

This test is for

Male, Female

Earliest reports in

144 hours

Test Preparation

No special preparation is required.

Understanding Anti - dsDNA Antibody (Double Stranded, Native) by IFA

What is Anti - dsDNA Antibody (Double Stranded, Native) by IFA?

The Anti - dsDNA Antibody (Double Stranded, Native) by IFA test is used to detect antibodies targeting the genetic material (DNA) within the cell’s nucleus (nucleated cells). These antibodies are indicative of certain autoimmune disorders, particularly systemic lupus erythematosus (SLE).

Anti-dsDNA (anti-double-stranded DNA) antibodies are a type of autoantibody that targets the body’s own DNA inside the cell’s nucleus. These antibodies are produced when the immune system mistakenly attacks the body’s own DNA. It is often seen in autoimmune diseases like systemic lupus erythematosus (SLE). The presence of anti-dsDNA antibodies causes inflammation and damage to various organs, signaling an immune system malfunction.

The Anti - dsDNA Antibody (Double Stranded, Native) by IFA test is performed when an individual experiences symptoms associated with SLE. Symptoms may include joint pain and stiffness, skin rashes, a butterfly-shaped rash on the face, kidney dysfunction, unexplained fever, etc. This test is particularly done when an individual has a positive antinuclear antibody (ANA) test. It can help track the disease in individuals already diagnosed with SLE and also check the risk in those with a family history SLE. It also helps tell lupus apart from other autoimmune conditions with similar symptoms.

The Anti - dsDNA Antibody (Double Stranded, Native) by IFA test uses a special method called Immunofluorescence Assay (IFA). This method helps detect antibodies in the blood using dyes to show if the antibodies are targeting the body's DNA.

A positive result means anti-dsDNA antibodies are present, which are common in lupus (SLE). However, it should be considered along with the patient's medical history. A negative result means no antibodies were found, but it doesn’t completely rule out lupus, as some people may have low levels that can’t be detected. Low to moderate levels of these antibodies can also appear in other conditions, like Sjögren’s syndrome or mixed connective tissue disease. So, the result should be correlated with symptoms, medical history, and additional tests.

No special preparation is required for this test. Inform the doctor about all the medications or supplements being taken, as well as the medical history, as these factors could potentially affect the test results.

Test result ranges may vary across laboratories. Abnormal test results require an expert interpretation. Never try to self-medicate at home based solely on these results, and always consult a doctor for a proper understanding of the test results.

What is Anti - dsDNA Antibody (Double Stranded, Native) by IFA used for?

The Anti - dsDNA Antibody (Double Stranded, Native) by IFA test is done:

To diagnose systemic lupus erythematosus (SLE) when there are symptoms like joint pain, rashes, or kidney issues.
To differentiate between SLE and other autoimmune disorders.
To monitor disease activity and track the progression of SLE.
To assess potential complications associated with SLE, such as kidney involvement.
In individuals with a family history of autoimmune diseases.

What does Anti - dsDNA Antibody (Double Stranded, Native) by IFA measure?

The Anti - dsDNA Antibody (Double Stranded, Native) by IFA test detects antibodies that attack a part of DNA called double-stranded DNA (dsDNA), which is found in the cells. These antibodies are often seen in autoimmune diseases like lupus (SLE), where the immune system mistakenly attacks the body’s own DNA. The presence of these antibodies in the blood may indicate the disease is active, causing flare-ups and possible damage, especially to the kidneys in lupus. This test helps doctors understand how serious the disease is, track how it’s progressing, and see if treatments are working.

Frequently Asked Questions about Anti - dsDNA Antibody (Double Stranded, Native) by IFA

Q. What is the Anti - dsDNA Antibody (Double Stranded, Native) by IFA test used for?

The Anti - dsDNA Antibody (Double Stranded, Native) by IFA test helps detect antibodies that attack a part of your DNA. It’s mainly used to diagnose autoimmune diseases, especially lupus (SLE), and to monitor the disease’s activity and progress.

Q. How is the Anti - dsDNA Antibody (Double Stranded, Native) by IFA test performed?

For this test, a blood sample is taken and tested using a method called Immunofluorescence Assay (IFA). This method uses dyes to see and identify the anti-dsDNA antibodies in the blood.

Q. What does a positive result mean?

A positive result means anti-dsDNA antibodies were found in your blood. This is strongly linked to diseases like lupus (SLE).

Q. What does a negative result mean?

A negative result means that anti-dsDNA antibodies were not detected in the blood. However, this doesn’t fully rule out autoimmune diseases like lupus, because some people may not have enough antibodies to detect. Your doctor will look at other symptoms and test results to make a diagnosis.

Q. Do I need any special preparation before taking the test?

No special preparation is required for the Anti - dsDNA Antibody (Double Stranded, Native) by IFA test. However, inform your doctor about any medications, supplements, or medical conditions, as they can affect the test results.

Q. When should I get the Anti - dsDNA Antibody (Double Stranded, Native) by IFA test?

Your doctor may recommend the test if you are showing symptoms suggestive of an autoimmune disease. These symptoms may include joint pain, skin rashes, fatigue, or kidney problems. It is also used for patients already diagnosed with autoimmune diseases like SLE to monitor disease activity and track treatment effectiveness.

Q. What should I do if my test result is positive?

Talk to your doctor about the result. They will consider your symptoms, medical history, and other tests. You may need more tests or follow-up appointments to confirm a diagnosis and decide on treatment.

Q. What is the difference between the ANA (anti-nuclear antibody) test and the Anti - dsDNA Antibody (Double Stranded, Native) by IFA test?

The ANA test looks for antibodies that attack many parts of the cell, including DNA, and is used to screen for autoimmune diseases. The anti-dsDNA test specifically checks for antibodies that attack double-stranded DNA, which is strongly linked to lupus (SLE). The anti-dsDNA test is more specific for lupus.

Q. When would a doctor recommend the ANA test versus the Anti - dsDNA Antibody (Double Stranded, Native) by IFA test?

The ANA test is often ordered first as a screening tool when a doctor suspects an autoimmune disease. If the ANA test is positive, the Anti - dsDNA Antibody (Double Stranded, Native) by IFA test is typically done to confirm the presence of lupus. The Anti - dsDNA Antibody (Double Stranded, Native) by IFA test is particularly useful when lupus is suspected due to its high specificity for the disease.

Q. How does Tata 1mg ensure accurate lab test results?

Tata 1mg ensures accurate lab test results through certified laboratories that use advanced technology and adhere to stringent quality control measures. This commitment to high standards guarantees reliable results.

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