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Cardiolipin Antibody Panel (IgA IgG IgM)

Also referred as

Cardiolipin Antibody Profile

For men & women

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144 hours

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3 tests

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The Cardiolipin Antibody Panel (IgA IgG IgM) measures three types of antibodies, immunoglobulin A (IgA), immunoglobulin G (IgG), and immunoglobulin M (IgM). These antibodies mistakenly target cardiolipin, a type of lipid in cell membranes. This panel is commonly used to help diagnose autoimmune disorders like antiphospholipid syndrome (APS), assess the risk of abnormal blood clotting events.

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Understanding Cardiolipin Antibody Panel (IgA IgG IgM)

The Cardiolipin Antibody Panel (IgA IgG IgM) detects antibodies that mistakenly target cardiolipin. These antibodies can indicate the presence of autoimmune disorders such as antiphospholipid syndrome (APS), systemic lupus erythematosus (SLE), and other conditions that lead to abnormal blood clotting. These antibodies may also be seen temporarily in individuals with acute infections, human immunodeficiency virus (HIV) infection, acquired immunodeficiency syndrome (AIDS), certain cancers, due to medications (such as phenytoin, penicillin, etc.), or asymptomatically in the elderly.

The Cardiolipin Antibody Panel (IgA IgG IgM) measures IgG, IgM antibodies that help determine the cause of an unexplained thrombotic episode (blood clots), thrombocytopenia (low platelet count), recurrent miscarriage (especially in the second and third trimesters of pregnancy), premature labor, and pre-eclampsia (pregnancy complication characterized by high blood pressure). Testing may be considered in individuals with symptoms suggestive of a thrombotic episode, such as pain and swelling in the extremities, shortness of breath, and headache. This panel can also be done in conjunction with lupus anticoagulant testing as a follow-up to a prolonged clotting time test (activated partial thromboplastin time, or APTT test). Additionally, this panel includes IgA testing, which may be helpful in patients who are negative for IgG and IgM, but still suspected of having APS, especially those with gastrointestinal or mucosal involvement. These antibodies may also appear temporarily during acute infections.

If cardiolipin antibodies are detected initially, the Cardiolipin Antibody Panel (IgA IgG IgM) is repeated 12 weeks later. Re-testing helps determine whether their presence is persistent or temporary. If an individual with an autoimmune disorder tests negative for cardiolipin antibodies, they may be retested later, as these antibodies may develop at any time in the future.

No special preparation is required for this panel. However, individuals should inform their doctor about any medications or supplements that they are taking, as these may affect the test results.

Lab test results may vary across laboratories. Self-medication should be avoided based solely on these results. Always consult a doctor for a proper understanding of the test results. The insights from this test help the doctor tailor appropriate treatment plans to mitigate the risk of clotting, its associated complications.

Please note: This is an outsourced test. The sample for this test is collected by TATA 1MG and processed at a NABL accredited partnered lab.

What does Cardiolipin Antibody Panel (IgA IgG IgM) measure?

Contains 3 tests

The Cardiolipin Antibody Panel (IgA IgG IgM) measures the levels of three types of cardiolipin antibodies: IgA, IgG, and IgM. These antibodies target cardiolipins, which are components of cell membranes and platelets. IgG and IgM antibodies are commonly measured in standard APS testing. These are closely associated with clotting risks and pregnancy-related complications. On the other hand, IgA antibodies may be present in certain cases where IgG and IgM are negative, particularly in individuals with mucosal or systemic autoimmune symptoms.

The presence of these antibodies indicates an immune system malfunction. This can increase the risk of thrombotic events, repeated miscarriages, organ damage, and other complications related to abnormal clotting.

By identifying and quantifying these antibodies, this panel aids in diagnosing autoimmune clotting disorders, guiding further medical management.

Anti Cardiolipin IgG Antibody

The Anti Cardiolipin IgG Antibody test detects specific immunoglobulins IgG antibodies, against cardiolipin, a phospholipid found in cell membranes. These antibodies can indicate autoimmune disorders such as antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE).

IgG antibodies are typically produced by the immune system later in an immune response and remain in the body for a longer time period, suggesting a more chronic or ongoing immune system activation. Therefore, the anticardiolipin IgG test is often used to diagnose chronic conditions or long-term immune responses, such as persistent blood clot formation in disorders like antiphospholipid syndrome (APS).

Know more about Anti Cardiolipin IgG Antibody

Anti Cardiolipin IgA Antibody

Anti Cardiolipin IgM Antibody

The Anti Cardiolipin IgM Antibody test detects specific immunoglobulins IgM antibodies against cardiolipin, a phospholipid found in cell membranes. These antibodies can indicate autoimmune disorders such as antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE).

IgM antibodies are typically the first antibodies produced by the immune system in response to an infection or antigen, and the presence of IgM antibodies in the blood sample may suggest recent or acute immune system activation. Thus, the Anti Cardiolipin IgM Antibody test is often used to diagnose acute conditions or recent immune responses, such as recent blood clot formation in disorders like antiphospholipid syndrome (APS).

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FAQs related to Cardiolipin Antibody Panel (IgA IgG IgM)

Why is the Cardiolipin Antibody Panel (IgA IgG IgM) important?

The Cardiolipin Antibody Panel (IgA IgG IgM) is important for detecting autoimmune disorders, such as antiphospholipid syndrome and lupus. Early detection of these disorders allows for prompt treatment, preventing serious complications like clot formation and stroke.

When should I get the Cardiolipin Antibody Panel (IgA IgG IgM)?

You can get the Cardiolipin Antibody Panel (IgA IgG IgM) if you have symptoms of an autoimmune disorder, such as unexplained blood clots, recurrent miscarriages, or prolonged PTT (which means that clotting is taking longer to occur than normal). It may also be done if you have been diagnosed with lupus to monitor your condition.

Does the Cardiolipin Antibody Panel (IgA IgG IgM) pose any risk?

No, the Cardiolipin Antibody Panel (IgA IgG IgM) is generally safe with minimal risks. However, you may feel slight discomfort during blood sample collection, but the chances of serious complications are extremely rare.

How often should I be tested?

The frequency of testing depends on your symptoms, medical history, and the doctor's discretion. If you have a known autoimmune condition, your doctor may suggest regular testing to monitor your condition.

Do I need to fast before the Cardiolipin Antibody Panel (IgA IgG IgM)?

No, fasting is not required before an Cardiolipin Antibody Panel (IgA IgG IgM). You can eat and drink normally.

What does positive cardiolipin mean?

A positive result for cardiolipin means that cardiolipin antibody is present in the blood. These can be due to several health conditions, like antiphospholipid syndrome (APS), systemic lupus erythematosus (SLE), deep vein thrombosis, recurrent miscarriages, etc.

What are the symptoms of antiphospholipid syndrome (APS)?

Common symptoms of APS are blood clots in the legs, discoloration, tenderness, and swelling of the legs, repeated miscarriages or stillbirths, chest pain, low platelets, discomfort in the arms, back, or neck, irregular heartbeat, etc.

Is there a cure for antiphospholipid syndrome?

There is no such cure for antiphospholipid syndrome yet. However, timely and proper treatment can greatly reduce the risk of excessive and irregular blood clotting. Furthermore, consuming an anticoagulant medicine as per the doctor’s prescription can help you manage the symptoms.

Why are all three antibodies tested together?

Testing IgA, IgG, and IgM together gives a more complete picture of your immune system activity. Some people may have only one type of antibody present, so testing all three helps in better diagnosis and monitoring of APS and SLE.

How does Tata 1mg ensure accurate lab test results?

Tata 1mg ensures accurate lab test results through certified laboratories. Tata 1mg uses advanced technology and adheres to stringent quality control measures. This commitment to high standards guarantees reliable results.

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Last Updated

5th Nov 2025