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Written by
Dr. Betina Chandolia
BDS, MDS - Oral Pathology and Microbiology
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Dr. Ashish Ranjan
MBBS, MD (Pharmacology)
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Adenosine Deaminase, Serum

Also known as Adenosine Deaminase (ADA) test
599660 9% Off
You need to provide
Blood
This test is for
Male, Female
Test Preparation
  1. No special preparation is required.

Understanding Adenosine Deaminase, Serum


What is Adenosine Deaminase, Serum?

The Adenosine Deaminase, Serum test is a blood test used to measure the level of adenosine deaminase, an enzyme vital to the functioning of the immune system. This test helps diagnose conditions like tuberculosis (TB) and assess immune system disorders, particularly those affecting white blood cells.

Adenosine deaminase (ADA) is an enzyme that plays a key role in purine metabolism, which is important for the breakdown of nucleotides (building blocks of DNA and RNA) in the body. It is primarily found in the liver, kidneys, and immune cells, especially lymphocytes. ADA is involved in the immune response and helps regulate the growth and function of T-cells, a type of white blood cell critical for immune defense. The Adenosine Deaminase, Serum test is commonly used to evaluate the presence of infections, particularly tuberculosis, which can cause inflammation and fluid accumulation in the lungs.

The Adenosine Deaminase, Serum test is recommended when a doctor suspects an infection such as tuberculosis, especially when there are signs of a lung infection or pleural effusion (fluid buildup around the lungs). Symptoms may include cough, chest pain, fever, shortness of breath, night sweats, etc. This test is also used to evaluate other conditions where the immune system might be compromised or overactive, such as in autoimmune diseases or certain types of cancers. Additionally, it is done when there are risk factors for TB, such as close contact with a TB-infected person, as well as to monitor treatment progress for infections like tuberculosis.

No special preparation is required for this test. However, inform the doctor about all the medications or supplements being taken, as these may affect the test results, potentially requiring adjustments or temporary discontinuation. Narrate the complete medical history to help doctors relate the clinical and laboratory findings.

Lab test results may vary across laboratories. Do not self-medicate. Always consult the doctor to understand the test results correctly. The insights from Adenosine Deaminase, Serum test will help doctors formulate the overall treatment plans.

What is Adenosine Deaminase, Serum used for?

The Adenosine Deaminase, Serum test is done: 

  • To diagnose and monitor tuberculosis, particularly when it affects the lungs or pleura.
  • To help differentiate between tuberculosis and other conditions (like lung cancer or sarcoidosis) that have similar respiratory symptoms.
  • To assess immune function and monitor conditions like HIV or autoimmune diseases.
  • To evaluate the response to treatment in individuals with tuberculosis or other infections.
  •  To evaluate the response to treatment for non-tuberculous mycobacterial infections.

What does Adenosine Deaminase, Serum measure?

The Adenosine Deaminase, Serum test measures the level of adenosine deaminase enzyme (ADA) in the blood or body fluids ( like pleural fluid, peritoneal fluid, pericardial fluid,etc.) ADA plays a key role in the immune system by helping regulate the function of T lymphocytes, which are vital for fighting infections. High ADA levels are typically associated with tuberculosis, as the body's immune response to the infection increases ADA production. Elevated ADA can also be seen in other diseases involving the immune system, such as certain cancers and immune deficiencies. On the contrary, low levels of ADA can indicate a weakened immune response, which may occur in conditions like immunodeficiencies or after immunosuppressive therapy.

Therefore, getting tested with the Adenosine Deaminase, Serum test helps doctors evaluate a wide range of infections and immune-related disorders.

Answers to Patient Concerns & Frequently Asked Questions (FAQs) about Adenosine Deaminase, Serum


Frequently Asked Questions about Adenosine Deaminase, Serum

Q. What is the Adenosine Deaminase, Serum test?

The Adenosine Deaminase, Serum test is a blood test that measures the level of adenosine deaminase, an enzyme produced primarily by the immune system. This test is used to help diagnose and monitor infections, particularly tuberculosis (TB) and assess immune system health.

Q. Why is the Adenosine Deaminase, Serum test performed?

This test is commonly used to diagnose tuberculosis (TB), especially when it affects the lungs or pleura (the lining around the lungs). It is also used to evaluate other conditions where the immune system may be involved, such as sarcoidosis, HIV, and certain cancers.

Q. How is the Adenosine Deaminase, Serum test performed?

A phlebotomist (a trained professional to perform blood draws) will clean your skin using an antiseptic alcohol cotton swab or wipe and take blood samples from your vein using a needle. The blood sample will be stored safely and transported to the laboratory for analysis.

Q. Do I need to fast before taking the Adenosine Deaminase, Serum test?

No fasting is required for this test. You can schedule it at your convenience without avoiding food or water beforehand.

Q. How frequently should this test be done?

The frequency of this test depends on your health condition, especially if you are undergoing treatment for pleural tuberculosis. Your doctor will provide guidance on how often you should get tested.

Q. What do elevated levels of ADA indicate?

Elevated ADA levels are commonly associated with tuberculosis, particularly in the lungs and pleura. However, they can also indicate other conditions like sarcoidosis, fungal infections, HIV, and some cancers. High levels are typically seen in cases of inflammation and immune activation.

Q. What do low levels of ADA indicate?

Low ADA levels can suggest a weakened immune system, which may occur in conditions like immunodeficiency diseases or after treatments that suppress the immune response, such as chemotherapy or immunosuppressive drugs.

Q. Can the Adenosine Deaminase, Serum test be used to diagnose tuberculosis on its own?

The Adenosine Deaminase, Serum test can be an important diagnostic tool for tuberculosis, but it is not definitive on its own. It is used in conjunction with other diagnostic methods, such as imaging tests, sputum cultures, and chest X-rays, to confirm the diagnosis of tuberculosis.

Q. How does Tata 1mg ensure accurate lab test results?

Tata 1mg ensures accurate lab test results through certified laboratories that use advanced technology and adhere to stringent quality control measures. This commitment to high standards guarantees reliable results.
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Adenosine Deaminase, Serum test price for other cities


Price inNew DelhiRs. 599
Price inMumbaiRs. 599
Price inFaridabadRs. 630
Price inBangaloreRs. 869
Price inRanchiRs. 550
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