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BCR-ABL Quantitative PCR (IS Scale)

BCR-ABL Quantitative PCR (IS Scale) near me in Secunderabad

Also referred as
BCR-ABL IS (International Scale)
p210 Transcript Fusion Quantitation by RT-PCR
For men & women
Earliest reports in
168 hours
Contains
1 test
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The BCR-ABL Quantitative PCR (IS Scale) is a highly sensitive molecular blood test that measures the BCR-ABL gene (a genetic mutation linked to chronic myeloid leukemia [CML] and some blood cancers) and quantifies BCR-ABL p210 fusion transcript levels on an international scale (IS). It helps diagnose CML, monitor treatment effectiveness, and detect minimal residual disease, assess prognosis, and guide therapy adjustments. It is widely available with Tata 1mg labs at an affordable price in Secunderabad.

The BCR-ABL Quantitative PCR (IS Scale) test is recommended for individuals diagnosed with CML. It is especially useful for individuals experiencing therapy resistance or treatment failure, as it detects mutations that may reduce the effectiveness of TKIs. Additionally, this test is important for monitoring treatment response over time, ensuring that the chosen therapy continues to work effectively.  The results guide doctors in choosing the best treatment plan by showing which medicine is likely to work better based on the individual’s genetic profile.

Usually, no special preparation is needed for this test. Eat and drink as per the daily routine. However, it is preferred to provide the clinical history before giving the sample.

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Understanding BCR-ABL Quantitative PCR (IS Scale)

Chronic myeloid leukemia (CML) is a slow-growing blood cancer that starts in the bone marrow. It can lead to the excessive production of abnormal white blood cells. It is commonly associated with the Philadelphia chromosome, a genetic abnormality caused by a translocation between chromosomes 9 and 22. This translocation results in the formation of the BCR-ABL1 fusion gene, which produces an abnormal enzyme called BCR-ABL1 tyrosine kinase. This enzyme promotes uncontrolled cell division, leading to the progression of CML.

The BCR-ABL Quantitative PCR (IS Scale) test is a vital diagnostic and monitoring tool for patients with CML and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). Both of these conditions are characterized by the presence of the BCR-ABL1 fusion gene. 

The BCR-ABL Quantitative PCR (IS Scale) test helps quantify the BCR-ABL1 transcript levels in the blood to monitor disease activity, and measures the amount of this fusion mRNA relative to a normal gene, with results standardized on an International Scale. This standardization allows for tracking the level of disease over time, assessing the effectiveness of tyrosine kinase inhibitor (TKI) therapies for treatment of CML, and defining key milestones like major molecular response (MMR) which indicates remission of disease.

The BCR-ABL Quantitative PCR (IS Scale) test is recommended for individuals diagnosed with CML. It is especially useful for individuals experiencing therapy resistance or treatment failure. By tracking the BCR-ABL1 transcript levels over time, clinicians can determine if the therapy is effective and if treatment needs to be adjusted. The results guide doctors in choosing the best treatment plan by showing which medicine is likely to work better based on the individual’s genetic profile.

Usually, no special preparation is needed for this test. Eat and drink as per the daily routine. However, it is preferred to provide the clinical history before giving the sample.

Test result ranges are approximate and may differ slightly between labs. Talk to the doctor about specific test results. The results will help them determine the medical condition and formulate an overall treatment plan. They may suggest lifestyle recommendations and medications if required to manage the condition.

Please note: This is an outsourced test. The sample for this test is collected by TATA 1MG and processed at a NABL accredited partnered lab.

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What does BCR-ABL Quantitative PCR (IS Scale) measure?

The BCR-ABL Quantitative PCR (IS Scale) test measures the amount of BCR-ABL fusion transcripts to diagnose chronic myeloid leukemia (CML) and Philadelphia chromosome (Ph)-positive acute lymphoblastic leukemia (ALL). This is used to monitor patient response to tyrosine kinase inhibitor (TKI) treatment. The test helps determine if treatment is effective, adjust medication, and monitor for disease recurrence or resistance. The test uses real-time quantitative PCR, which is highly sensitive and can detect even minute levels of residual disease. The results are reported on an International Scale (IS), which allows for standardization and comparability of results across different laboratories. 

A low or undetectable level means the treatment is working well, while a higher or rising level may suggest relapse or resistance. 

FAQs related to BCR-ABL Quantitative PCR (IS Scale) in Secunderabad

This test checks for a specific gene change (called BCR-ABL) in the blood. This gene is often found in people with certain types of blood cancer, like chronic myeloid leukemia (CML).
Doctors use this test to confirm if you have CML or a related leukemia, to track how well your treatment is working, and to check the recurrence of the disease.
A small sample of blood is taken from your arm with a needle. The sample is then tested in a lab using a method called PCR, which looks for and measures the BCR-ABL gene.
No, you do not need to stop eating or drinking before this test.
The frequency of the test depends on factors like the stage of the disease and how well the patient is responding to treatment. Your doctor will recommend the appropriate schedule based on your specific condition.
Yes. In Secunderabad, you can schedule the BCR-ABL Quantitative PCR (IS Scale) test near you with Tata 1mg Labs. The test is easy to book, cost-effective, and available with a comprehensive report.
Yes, home sample collection for the BCR-ABL Quantitative PCR (IS Scale) test is readily available in Secunderabad. Tata 1mg Labs allows you to choose a date and time that suits your schedule for sample collection.
If you want to schedule the BCR-ABL Quantitative PCR (IS Scale) test with Tata 1mg Labs in Secunderabad, the procedure is fairly easy and hassle-free. Follow these steps to book a test: 1). Visit the Lab Tests section on the Tata 1mg website. 2). Add the test you want to the cart. 3). Pick a time and date slot according to your convenience; however, do consider the necessary prerequisites while scheduling a test. 4). You will receive a notification with all the details once the test is scheduled.
Tata 1mg Labs is a pocket-friendly platform for booking lab tests in Secunderabad. The BCR-ABL Quantitative PCR (IS Scale) test is available at an affordable price of Rs. 6179.
At Tata 1mg Labs, we understand the importance of timely results. We strive to provide fast turnaround times for test results, allowing you to get the information you need promptly. On average, we take 168 hours to provide the reports of the BCR-ABL Quantitative PCR (IS Scale) test in Secunderabad.
Content created by
Written by:
Shweta Prakash
MSc, BSc
Reviewed by:
Dr. Swati Gupta (Anand)
MD Lab Medicine, MBBS
Want to know moreRead our editorial policy
Last Updated6th Nov 2025

BCR-ABL Quantitative PCR (IS Scale) test price for other cities

Price inNew DelhiRs. 6119
Price inHyderabadRs. 6179
Price inBangaloreRs. 6529
Price inGurgaonRs. 6119
Price inMumbaiRs. 6299

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BCR-ABL Quantitative PCR (IS Scale)