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BCR-ABL Quantitative PCR (IS Scale) near me in Secunderabad

Also known as BCR-ABL IS (International Scale), p210 Transcript Fusion Quantitation by RT-PCR
You need to provide
Blood
This test is for
Male, Female
Earliest reports in
168 hours
Test Preparation
  1. Clinical history is preferred.

Understanding BCR-ABL Quantitative PCR (IS Scale) in Secunderabad


What is BCR-ABL Quantitative PCR (IS Scale) in Secunderabad?

The BCR-ABL Quantitative PCR (IS Scale) is a highly sensitive molecular blood test that measures the BCR-ABL gene (a genetic mutation linked to chronic myeloid leukemia [CML] and some blood cancers) and quantifies BCR-ABL p210 fusion transcript levels on an international scale (IS). It helps diagnose CML, monitor treatment effectiveness, and detect minimal residual disease, assess prognosis, and guide therapy adjustments. It is widely available with Tata 1mg labs at an affordable price in Secunderabad.

The BCR-ABL Quantitative PCR (IS Scale) test is recommended for individuals diagnosed with CML. It is especially useful for individuals experiencing therapy resistance or treatment failure, as it detects mutations that may reduce the effectiveness of TKIs. Additionally, this test is important for monitoring treatment response over time, ensuring that the chosen therapy continues to work effectively.  The results guide doctors in choosing the best treatment plan by showing which medicine is likely to work better based on the individual’s genetic profile.

Usually, no special preparation is needed for this test. Eat and drink as per the daily routine. However, it is preferred to provide the clinical history before giving the sample.

What does BCR-ABL Quantitative PCR (IS Scale) measure?

The BCR-ABL Quantitative PCR (IS Scale) test measures the amount of BCR-ABL fusion transcripts to diagnose chronic myeloid leukemia (CML) and Philadelphia chromosome (Ph)-positive acute lymphoblastic leukemia (ALL). This is used to monitor patient response to tyrosine kinase inhibitor (TKI) treatment. The test helps determine if treatment is effective, adjust medication, and monitor for disease recurrence or resistance. The test uses real-time quantitative PCR, which is highly sensitive and can detect even minute levels of residual disease. The results are reported on an International Scale (IS), which allows for standardization and comparability of results across different laboratories. 

A low or undetectable level means the treatment is working well, while a higher or rising level may suggest relapse or resistance. 

Frequently Asked Questions about BCR-ABL Quantitative PCR (IS Scale) in Secunderabad


Q. What is the BCR-ABL Quantitative PCR (IS Scale) test?

This test checks for a specific gene change (called BCR-ABL) in the blood. This gene is often found in people with certain types of blood cancer, like chronic myeloid leukemia (CML).

Q. Why do I need this test?

Doctors use this test to confirm if you have CML or a related leukemia, to track how well your treatment is working, and to check the recurrence of the disease.

Q. How is the test done?

A small sample of blood is taken from your arm with a needle. The sample is then tested in a lab using a method called PCR, which looks for and measures the BCR-ABL gene.

Q. Do I need to fast before the test?

No, you do not need to stop eating or drinking before this test.

Q. How often do I need this test?

The frequency of the test depends on factors like the stage of the disease and how well the patient is responding to treatment. Your doctor will recommend the appropriate schedule based on your specific condition.

Q. Can I schedule the BCR-ABL Quantitative PCR (IS Scale) test online in Secunderabad near me?

Yes. In Secunderabad, you can schedule the BCR-ABL Quantitative PCR (IS Scale) test near you with Tata 1mg Labs. The test is easy to book, cost-effective, and available with a comprehensive report.

Q. Is a home sample collection facility available for the BCR-ABL Quantitative PCR (IS Scale) test in Secunderabad with Tata 1mg Labs?

Yes, home sample collection for the BCR-ABL Quantitative PCR (IS Scale) test is readily available in Secunderabad. Tata 1mg Labs allows you to choose a date and time that suits your schedule for sample collection.

Q. How can I schedule the BCR-ABL Quantitative PCR (IS Scale) test with Tata 1mg Labs in Secunderabad?

If you want to schedule the BCR-ABL Quantitative PCR (IS Scale) test with Tata 1mg Labs in Secunderabad, the procedure is fairly easy and hassle-free. Follow these steps to book a test: 1). Visit the Lab Tests section on the Tata 1mg website. 2). Add the test you want to the cart. 3). Pick a time and date slot according to your convenience; however, do consider the necessary prerequisites while scheduling a test. 4). You will receive a notification with all the details once the test is scheduled.

Q. What is the price of the BCR-ABL Quantitative PCR (IS Scale) test at Tata 1mg Labs in Secunderabad?

Tata 1mg Labs is a pocket-friendly platform for booking lab tests in Secunderabad. The BCR-ABL Quantitative PCR (IS Scale) test is available at an affordable price of Rs. 6179.

Q. What is the estimated turnaround time for the results of the BCR-ABL Quantitative PCR (IS Scale) test in Secunderabad?

At Tata 1mg Labs, we understand the importance of timely results. We strive to provide fast turnaround times for test results, allowing you to get the information you need promptly. On average, we take 168 hours to provide the reports of the BCR-ABL Quantitative PCR (IS Scale) test in Secunderabad.
+ more

BCR-ABL Quantitative PCR (IS Scale) test price for other cities


Price inHyderabadRs. 6179
Price inMumbaiRs. 6299
Price inNew DelhiRs. 6119
Price inBangaloreRs. 6529
Price inGurgaonRs. 6119
+ more

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References

  1. Kockerols CCB, Valk PJM, Levin MD, Pallisgaard N, Cornelissen JJ, Westerweel PE. Digital PCR for BCR-ABL1 Quantification in CML: Current Applications in Clinical Practice. Hemasphere. 2020 Nov 24;4(6):e496. [Accessed 8 May 2025]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710259/ External Link
  2. Machado MP, Tomaz JP, Lorand-Metze I, de Souza CA, Vigorito AC, Delamain MT, Bendit I, Pereira NF, Pagnano KB. Monitoring of BCR-ABL levels in chronic myeloid leukemia patients treated with imatinib in the chronic phase - the importance of a major molecular response. Rev Bras Hematol Hemoter. 2011;33(3):211-5. [Accessed 8 May 2025]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415739/ External Link
  3. Ayatollahi H, Keramati MR, Shirdel A, Kooshyar MM, Raiszadeh M, Shakeri S, Sadeghian MH. BCR-ABL fusion genes and laboratory findings in patients with chronic myeloid leukemia in northeast Iran. Caspian J Intern Med. 2018 Winter;9(1):65-70. [Accessed 8 May 2025]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771363/ External Link
  4. Giri S, Pathak R, Martin MG, Bhatt VR. Characteristics and survival of BCR/ABL negative chronic myeloid leukemia: a retrospective analysis of the Surveillance, Epidemiology and End Results database. Ther Adv Hematol. 2015 Dec;6(6):3-12. [Accessed 8 May 2025]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649605/ External Link
  5. Leukemia [Internet]. NIH: National Cancer Institute; [Accessed 8 May 2025]. Available from: https://www.cancer.gov/types/leukemia External Link

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