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Hemoglobin HPLC/Electrophoresis with CBC near me in Dombivli

Also referred as
Hb Electrophoresis
+2
Abnormal Hb studies
Hemoglobin variant analysis
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The Hemoglobin HPLC/Electrophoresis with CBC test is a specialized blood test used to identify and quantify different types of hemoglobin present in blood using HPLC along with complete blood count (CBC). The test helps identify abnormal hemoglobin variants and assess red blood cell characteristics, supporting the screening and diagnosis of inherited blood disorders, such as thalassemia and sickle cell disease. It is available at an affordable price in Dombivli with Tata 1mg Labs.

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What does Hemoglobin HPLC/Electrophoresis with CBC measure?

Contains 22 tests

The Hemoglobin HPLC/Electrophoresis with CBC test identifies and measures different types of hemoglobin in the blood and assesses blood cell parameters through a CBC to help diagnose and keep track of certain blood disorders. These types of hemoglobin include: adult type (HbA2), fetal type (HbF), hemoglobin S (HbS), hemoglobin C (HbC), and hemoglobin E (HbE), among others.

The CBC measures parameters such as:

  • Hemoglobin (Hb): Measures the amount of hemoglobin in the blood.
  • Hematocrit (HCT): Measures the proportion of blood made up of red blood cells.
  • Red blood cell (RBC) count: Measures the number of red blood cells in the blood.
  • Red blood cell indices: Include MCV, MCH, MCHC, and RDW, which provide information about the size, hemoglobin content, and variation in the size of red blood cells.
  • White blood cell (WBC) count and platelet count: Provide information about other blood cell types.

Normal hemoglobin types:

  • Hemoglobin A (HbA): The main type of hemoglobin in healthy adults.
  • Hemoglobin F (HbF): Found in unborn babies and newborns. It is slowly replaced by HbA after birth.

If the levels of HbA or HbF are not normal, it may indicate certain types of anemia. The interpretation depends on the overall hemoglobin pattern and CBC findings.

Abnormal hemoglobin types:

  • Hemoglobin S (HbS): Found in people with sickle cell anemia. It causes red blood cells to become stiff and sickle-shaped, leading to pain and other health problems.
  • Hemoglobin C (HbC): Linked to a condition called hemolytic anemia, where red blood cells break down faster than normal.
  • Hemoglobin E (HbE): Common in people from Southeast Asia. It may cause mild anemia or sometimes no symptoms at all in the heterozygous state.
  • Hemoglobin D (HbD): Causes mild hemolytic anemia and mild to moderate spleen enlargement. The Hb D Punjab variant is most commonly seen in people from Gujarat and among Sikhs of Punjab.

The HPLC or electrophoresis pattern, together with CBC findings and clinical history, helps the doctor assess whether further testing is required.

Hemoglobin HPLC/Electrophoresis

The CBC (Complete Blood Count) test measures the number of red blood cells (RBCs), white blood cells (WBCs), and platelets. Each of these blood cells performs essential functions–RBCs carry oxygen from your lungs to the various body parts, WBCs help fight infections and other diseases, and platelets help your blood to clot. Therefore, determining their levels can provide significant health information. A CBC test also determines the hemoglobin level, a protein in RBC that carries oxygen from the lungs to the rest of your body. Evaluating all these components together can provide important information about your overall health.

Know more about CBC (Complete Blood Count)

  • Differential Leukocyte Count

  • There are five types of WBCs: neutrophils, lymphocytes, monocytes, eosinophils, and basophils. A Differential Leukocyte Count test measures the percentage of each type of WBC in the blood. Leukocytes or WBCs are produced in the bone marrow and defend the body against infections and diseases. Each type of WBC plays a unique role to protect against infections and is present in different numbers.

    This further contains

    • Differential Neutrophil Count
    • Differential Lymphocyte Count
    • Differential Monocyte Count
    • Differential Eosinophil Count
    • Differential Basophil Count
  • Red Blood Cell Count

  • The Red Blood Cell Count test measures the total number of red blood cells in your blood. RBCs are the most abundant cells in the blood with an average lifespan of 120 days. These cells are produced in the bone marrow and destroyed in the spleen or liver. Their primary function is to help carry oxygen from the lungs to different body parts. The normal range of RBC count can vary depending on age, gender, and the equipment and methods used for testing.

  • Hb (Hemoglobin)

  • The Hb (Hemoglobin) test measures the concentration of hemoglobin in your blood. Hemoglobin binds oxygen molecules and carries them to body tissues while removing carbon dioxide. Low hemoglobin suggests reduced oxygen-carrying capacity. It can be due to anemia, bleeding, nutritional deficiencies (iron, vitamin B12, folate), or chronic disease. High hemoglobin may occur in dehydration, living at high altitudes, smoking, or diseases like polycythemia vera.

  • Platelet Count

  • The Platelet Count test measures the average number of platelets in the blood. Platelets are disk-shaped tiny cells originating from large cells known as megakaryocytes, which are found in the bone marrow. After the platelets are formed, they are released into the blood circulation. Their average life span is 7-10 days. 

    Platelets help stop the bleeding, whenever there is an injury or trauma to a tissue or blood vessel, by adhering and accumulating at the injury site and releasing chemical compounds that stimulate the gathering of more platelets. A loose platelet plug is formed at the site of injury and this process is known as primary hemostasis. These activated platelets support the coagulation pathway that involves a series of steps, including the sequential activation of clotting factors; this process is known as secondary hemostasis. After this step, there is a formation of fibrin strands that form a mesh incorporated into and around the platelet plug. This mesh strengthens and stabilizes the blood clot so that it remains in place until the injury heals. After healing, other factors come into play and break the clot down so that it gets removed. In case the platelets are not sufficient in number or not functioning properly, a stable clot might not form. These unstable clots can result in an increased risk of excessive bleeding. 

  • Total Leukocyte Count

  • The Total Leukocyte Count test measures the numbers of all types of leukocytes, namely neutrophil, lymphocyte, monocyte, eosinophil, and basophil, in your blood. Leukocytes or WBCs are an essential part of our immune system. These cells are produced in the bone marrow and defend the body against infections and diseases. Each type of WBC plays a unique role to protect against infections and is present in different numbers.

  • Hematocrit

  • The Hematocrit test measures the proportion of red blood cells (RBCs) in your blood as a percentage of the total blood volume. It is a crucial part of a complete blood count (CBC) and helps in assessing your blood health. RBCs are responsible for carrying oxygen from the lungs to different parts of the body. The hematocrit test provides valuable information about your blood's oxygen-carrying capacity.

    Higher-than-normal amounts of RBCs produced by the bone marrow can cause the hematocrit to increase, leading to increased blood density and slow blood flow. On the other hand, lower-than-normal hematocrit can be caused by low production of RBCs, reduced lifespan of RBCs in circulation, or excessive bleeding, leading to a reduced amount of oxygen being transported by RBCs. Monitoring your hematocrit levels is essential for diagnosing and managing various blood-related disorders.

  • Mean Corpuscular Volume

  • The Mean Corpuscular Volume test measures the average size of your red blood cells, which carry oxygen through your body. This test tells whether your RBCs are of average size and volume or whether they are bigger or smaller.

  • Mean Corpuscular Hemoglobin

  • An MCH test measures the average amount of hemoglobin in a single red blood cell (RBC). Hemoglobin is an iron-containing protein in RBCs, and its major function is to transport oxygen from the lungs to all body parts. This test provides information about how much oxygen is being delivered to the body by a certain number of RBCs.

  • Mean Corpuscular Hemoglobin Concentration

  • An MCHC test measures the average amount of hemoglobin in a given volume of RBCs. MCHC is calculated by dividing the amount of hemoglobin by hematocrit (volume of blood made up of RBCs) and then multiplying it by 100. 

  • Absolute Leucocyte Count

  • The Absolute Leucocyte Count test measures the total number of white blood cells (leucocytes) in the given volume of blood. It examines different types of white blood cells such as neutrophils, lymphocytes, monocytes, basophils and eosinophils. These cells tell about the status of the immune system and its ability to fight off infections and other conditions like inflammation, allergies, bone marrow disorders etc.

    This further contains

    • Absolute Lymphocyte Count (ALC)
    • Absolute Neutrophil Count
    • Absolute Basophil Count
    • Absolute Monocyte Count
    • Absolute Eosinophil Count
  • Mean Platelet Volume

  • An MPV test measures the average size of the platelets in your blood. Platelets are disk-shaped tiny cells originating from large cells known as megakaryocytes, which are found in the bone marrow. After the platelets are formed, they are released into the blood circulation. Their average life span is 7-10 days. 

    Platelets help stop bleeding whenever there is an injury or trauma to a tissue or blood vessel by adhering and accumulating at the injury site, and by releasing chemical compounds that stimulate the gathering of more platelets. After these steps, a loose platelet plug is formed at the site of injury, and this process is known as primary hemostasis. These activated platelets support the coagulation pathway that involves a series of steps including the sequential activation of clotting factors; this process is known as secondary hemostasis. After this, there is a formation of fibrin strands that form a mesh incorporated into and around the platelet plug. This mesh strengthens and stabilizes the blood clot so that it remains in place until the injury heals. After healing, other factors come into play and break the clot down so that it gets removed. In case the platelets are not sufficient in number or are not functioning properly, a stable clot might not form. These unstable clots can result in an increased risk of excessive bleeding. 

  • PDW

  • The PDW test reflects variability in platelet size, and is considered a marker of platelet function and activation (clot formation in case of an injury). This marker can give you additional information about your platelets and the cause of a high or low platelet count. Larger platelets are usually younger platelets that have been recently released from the bone marrow, while smaller platelets may be older and have been in circulation for a few days. Higher PDW values reflect a larger range of platelet size, which may result from increased activation, destruction and consumption of platelets.

  • RDW CV

  • The RDW CV test which is part of red cell indices, helps identify characteristics of red blood cells. RDW (red cell distribution width) measures the variations in the sizes of red blood cells, indicating how much they differ from each other in a blood sample. RDW is expressed as RDW-CV, a coefficient of variation. A higher RDW may suggest more variation in red cell sizes, while a lower RDW indicates more uniform red cell sizes.

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Hemoglobin HPLC/Electrophoresis with CBC test price for other cities

Price inBangaloreRs. 1169
Price inNew DelhiRs. 1059
Price inGurgaonRs. 1039
Price inKolkataRs. 1039
Price inMumbaiRs. 1129
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FAQs related to Hemoglobin HPLC/Electrophoresis with CBC in Dombivli

The Hemoglobin HPLC/Electrophoresis with CBC is a blood test that identifies and measures different types of hemoglobin through a HB-HPLC and evaluates blood cell parameters through a Complete Blood Count (CBC). It can help assess conditions such as anemia, thalassemia, sickle cell disorders, and other hemoglobin abnormalities.
Your doctor may recommend the Hemoglobin HPLC/Electrophoresis with CBC if you have unexplained anemia, abnormal CBC results, a family history of hemoglobin disorders, or symptoms that may be associated with a blood disorder. It may also be recommended as part of screening when an inherited hemoglobin disorder is suspected.
The test may be recommended for people with unexplained or persistent anemia, abnormal red blood cell indices, suspected thalassemia or sickle cell disorders, or a family history of hemoglobin disorders. It may also be advised before or during pregnancy in certain situations based on medical history and screening requirements.
During the test, your phlebotomist will collect the blood sample in a vial/test tube. The test tube is then submitted to the labs for analysis. An electric current is passed through the blood sample, which helps to segregate different hemoglobin into separate bands. Your blood sample is finally compared to a normal hemoglobin sample to give accurate test results.
There are minimal risks associated with an Hemoglobin HPLC/Electrophoresis with CBC test. You might experience slight pain or bruising at the spot where the needle was inserted. The risk of infection or excessive bleeding is very low.
Yes, Tata 1mg Labs offers an Hemoglobin HPLC/Electrophoresis with CBC test in Dombivli near you. The test is easy to book, is pocket-friendly, and comes with a comprehensible report.
Yes, home sample collection for an Hemoglobin HPLC/Electrophoresis with CBC test is readily available in Dombivli. Tata 1mg Labs allows you to choose a date and time that suits your schedule for sample collection.
If you want to schedule an Hemoglobin HPLC/Electrophoresis with CBC test with Tata 1mg Labs in Dombivli, the procedure is fairly easy and hassle-free. Follow these steps to book a test: 1). Visit the Lab Tests section on the Tata 1mg website. 2). Add the test you want in the cart. 3). Pick a time and date slot according to your convenience; however, do consider the necessary prerequisites while scheduling a test. 4). You will receive a notification with all the details once the test is scheduled.
Tata 1mg Labs is a pocket-friendly platform for booking lab tests in Dombivli. An Hemoglobin HPLC/Electrophoresis with CBC test is available at an affordable price of Rs. 1129.
At Tata 1mg Labs, we understand the importance of timely results. We strive to provide fast turnaround times for test results, allowing you to get the information you need promptly. On average, we take 54 hours to provide the reports of an Hemoglobin HPLC/Electrophoresis with CBC test in Dombivli.
The e-report of your Hemoglobin HPLC/Electrophoresis with CBC can be found on the Tata 1mg app in downloadable PDF form. This allows you to access your test results at convenience and securely share them with your healthcare provider for further consultation and guidance regarding your overall health. You can also opt for a hard copy of the reports at a minimal price.

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