Information about Topotecan

Topotecan Uses

Topotecan is used in the treatment of ovarian cancer.

How Topotecan works

Topotecan is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase I) involved in DNA multiplication of the cancer cells. This slows the growth of cancer cells and eventually kills them.
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MD (Pharmacology), MBBS
Last updated
22 Feb 2021 | 12:52 PM (UTC)

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Available Medicine for Topotecan

TopotecUnited Biotech Pvt Ltd
59781 variant(s)
TopoquisFresenius Kabi India Pvt Ltd
55001 variant(s)
HycamtinGlaxo SmithKline Pharmaceuticals Ltd
82501 variant(s)
TopocanVenus Remedies Ltd
2137 to ₹50002 variant(s)
TopotelFresenius Kabi India Pvt Ltd
4498 to ₹71722 variant(s)
AdmatopAdmac Pharma Ltd
52991 variant(s)

Expert advice for Topotecan

  • Topotecan helps treat ovarian cancer.
  • It is given by a drip into a vein (intravenous infusion).
  • Do not drive or operate machinery as Topotecan may cause tiredness, drowsiness or weakness.
  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
  • Your doctor may get regular blood tests done to monitor your blood cells during treatment with this medicine.
  • Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.

Frequently asked questions for Topotecan


Q. How often is Topotecan given?

Generally Topotecan treatment is for 4 cycles of 21 day each, patient is given Topotecan for first 5 days of each cycle.

Q. Does Topotecan cause hair loss?

Yes, Topotecan may cause temporary hair loss.

Q. Does Topotecan cause flare reaction?

Yes, Topotecan may cause flare reaction.

Q. How long does Topotecan take to work?

Topotecan may start its action once the infusion is started, however, the complete effect may be assessed only after completion of 4 cycles.

Q. Is Topotecan a vesicant?

Topotecan is a vesicant (irritant).

Q. Is Topotecan effective?

Yes Topotecan is effective if used at prescribed doses for the prescribed duration as advised by your doctor.

Q. What is Topotecan chemotherapy?

It is a treatment therapy that includes Topotecan with or without combination of other drugs in treatment of cancer (Usually ovarian or lung cancer).

Q. How is Topotecan administered?

Topotecan is either administered orally as a capsule or as an intravenous Infusion in the arm over a period of 30 min.


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