Xospata 40mg Tablet is a prescription medicine used to treat acute myeloid leukemia (AML) that has returned or not improved after previous treatments. It works by blocking certain enzymes that promote the growth of cancer cells, thereby inhibiting their multiplication and aiding in controlling the disease.

Xospata 40mg Tablet may be taken with or without food. Take it in the exact dose and duration prescribed by your doctor. Take it at the same time each day to maintain consistent levels in your body. To maximize the benefits, maintain regular appointments with your doctor and report any side effects or concerns.

Common side effects of Xospata 40mg Tablet include fatigue, nausea, diarrhea, constipation, muscle or joint pain, and elevated liver enzymes. If any of these side effects persist or worsen, discuss them with your doctor. They may be able to provide supportive treatments or adjust your dosage. However, if you experience severe symptoms such as difficulty breathing, chest pain, rapid weight gain, or swelling, consult your doctor immediately.

While taking Xospata 40mg Tablet, avoid using other medicines or supplements without consulting your doctor. Inform your doctor if you have a history of heart problems, as this medicine can cause changes in heart rhythm. Use effective contraception during treatment and for some time after the last dose, as Xospata 40mg Tablet can harm an unborn baby. Do not breastfeed during treatment and for at least two months after the final dose.

Uses of Xospata Tablet

Treatment of Blood Cancer (Acute myeloid leukemia)

Benefits of Xospata Tablet

In Treatment of Blood Cancer (Acute myeloid leukemia)

In patients with acute myeloid leukemia (AML), Xospata 40mg Tablet helps by slowing or stopping the growth of cancer cells in the blood and bone marrow, improving the chances of remission. Xospata 40mg Tablet helps improve quality of life and offers hope for longer survival and better outcomes.

Side effects of Xospata Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Xospata

Constipation
Mucositis
Edema (swelling)
Breathlessness
Increased transaminase level in blood
Eye disorder
Headache
Dizziness
Vomiting
Renal impairment
Hypotension (low blood pressure)
Fatigue
Joint pain
Fever
Rash
Diarrhea
Nausea
Cough

How to use Xospata Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Xospata 40mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Xospata Tablet works

Xospata 40mg Tablet works by inhibiting the activity of FLT3, a receptor tyrosine kinase that is often mutated and overactive in certain cases of acute myeloid leukemia (AML). By blocking FLT3 signaling, it helps disrupt the growth and survival of leukemia cells, ultimately slowing their proliferation and promoting their destruction. This targeted action helps to control the progression of AML and improve treatment outcomes.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Xospata 40mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Xospata 40mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Xospata 40mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Xospata 40mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

SAFE IF PRESCRIBED

Xospata 40mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Xospata 40mg Tablet is recommended.

Liver

SAFE IF PRESCRIBED

Xospata 40mg Tablet is safe to use in patients with liver disease. No dose adjustment of Xospata 40mg Tablet is recommended.

What if you forget to take Xospata Tablet?

If you miss a dose of Xospata 40mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

No substitutes found for this medicine

Quick tips

Your doctor will monitor your liver and kidney function regularly while you are on Xospata 40mg Tablet. Be sure to attend all scheduled appointments for blood tests and other evaluations.
Always tell your doctor about any other medications, including over-the-counter drugs and supplements. Some medications may interact with Gilteritinib, affecting its effectiveness or increasing side effects.
Drink plenty of water and maintain a balanced diet to help manage potential side effects like nausea or fatigue.
Like many cancer treatments, Xospata 40mg Tablet may make your skin more sensitive to sunlight. Use sunscreen and avoid prolonged sun exposure to protect your skin.

Fact Box

Chemical Class

Phenylpiperidines

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Tyrosine Kinase Inhibitors (TKIs)

Patient concerns

She is suffering from chronic myeloid leukemia

Dr. Deepak Kumar Soni

Ayurveda

Hi Kindly consult to Ayurvedic doctor at your local city area , face to face consult is needed.

Features suggestive of acute myeloid leukemia Is this disease is curable if no than how much time did the patient have with & without treatment

Dr. Sanjay Singh Rai

Medical Oncology and Hematology

Less chances of cureHowever treatment is possible

I'm detected with acute lymphoblastic leukemia taking alloepathy treatment but finding it costly want to start homeopathy treatment along with it kindly help

Dr. Manju Singh

Homeopathy

I would like to recommend you that if you want to start homeopathy then you should visit a homeopathic physician who is nearer to your home because your case require a detail case taking then your medicine will be selected on the basis of your symptoms.

How is Xospata 40mg Tablet taken?

Xospata 40mg Tablet is taken orally. Your doctor will provide the exact dosage and schedule based on your condition. It is important to follow your doctor’s instructions carefully and take the medication regularly.

Is Xospata 40mg Tablet safe during pregnancy or breastfeeding?

Xospata 40mg Tablet is not considered safe during pregnancy or breastfeeding. It can harm an unborn baby and should not be used by pregnant women unless absolutely necessary and prescribed by a doctor. Women of childbearing age should use effective contraception during treatment to prevent pregnancy. Similarly, breastfeeding is not recommended during treatment with Xospata 40mg Tablet and for at least two months after the final dose, as the medication may pass into breast milk and harm the infant. Always consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding before starting treatment with Xospata 40mg Tablet.

Can Xospata 40mg Tablet be used for patients with other types of leukemia?

Xospata 40mg Tablet is specifically used for treating relapsed or refractory acute myeloid leukemia (AML) with FLT3 mutations. It may not be suitable for other types of leukemia. Your doctor will assess your condition and determine the best treatment approach for you.

Can I take Xospata 40mg Tablet if I have kidney or liver problems?

If you have kidney or liver problems, you should inform your doctor before starting Xospata 40mg Tablet. Regular blood tests may be conducted to evaluate how well your liver and kidneys are functioning during the course of treatment. Always follow your doctor’s guidance and avoid taking Xospata 40mg Tablet without medical advice if you have underlying kidney or liver conditions.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Gilteritinib [Prescribing Information]. Northbrook, Illinois: Astellas Pharma US, Inc.; 2019. [Accessed 10/01/2024] (online) Available from:

Marketer details

Name: Astellas Pharma Inc

Address: Astellas Pharma India Pvt Ltd, 301, 3rd Floor, C and B Square, 127 Andheri Kurla Road, Chakala, Andheri East, Mumbai 400 069.

Country of origin: Japan
Expires on or after: November, 2025

A licensed vendor partner from your nearest location will deliver Xospata 40mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India