Sizonorm Forte Tablet

Chlordiazepoxide (50mg)+ Trifluoperazine (5mg)+ Trihexyphenidyl (2mg)

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Sizonorm Forte Tablet is used in the treatment of schizophrenia. It is a combination medicine which calms the brain by decreasing the abnormal and excessive activity of the nerve cells. It also blocks the action of a chemical messenger in the brain that affects thoughts and mood.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 30 Jul 2026 | 01:02 AM (IST)

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General Information

Contains

Chlordiazepoxide (50mg)+ Trifluoperazine (5mg)+ Trihexyphenidyl (2mg)

Marketer

Crescent Therapeutics Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Sizonorm Forte Tablet should be taken with food. It is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor as it has habit-forming potential. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop taking this medication suddenly as it may cause withdrawal symptoms.

Some common side effects of this medicine include nausea, constipation, confusion, dryness in mouth, and difficulty in urination. It may also cause dizziness and sleepiness. So, do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can make drowsiness worse. This medicine can lead to weight gain and to prevent it you can eat a healthy balanced diet, avoid snacking with high-calorie food and exercise regularly. Your doctor may advise for regular monitoring of blood sugar and cholesterol levels also.

Take caution while taking medicine if you are suffering from liver or kidney disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. Avoid wearing contact lenses as it may cause dry eyes as well. It is important to inform your doctor if you suffer from glaucoma or have trouble in passing urine.

Uses of Sizonorm Forte Tablet

Schizophrenia

Benefits of Sizonorm Forte Tablet

Schizophrenia
Schizophrenia is a mental disorder in which a person’s thinking ability, feelings and behavior become abnormal. Sizonorm Forte Tablet helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life.

Side effects of Sizonorm Forte Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Sizonorm Forte

Nausea
Constipation
Sedation
Weight gain
Confusion
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Memory impairment
Increased prolactin level in blood
Dizziness
Tiredness
Blurred vision
Dryness in mouth
Difficulty in urination
Nervousness
Uncoordinated body movements
Depression

How to use Sizonorm Forte Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sizonorm Forte Tablet should be taken with or after food.

How Sizonorm Forte Tablet works

Sizonorm Forte Tablet is a combination of three medicines: Chlordiazepoxide, Trifluoperazine and Trihexyphenidyl. Chlordiazepoxide is a benzodiazepine (BZD) which works by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in the brain. Trifluoperazine is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood. Trihexyphenidyl is an anticholinergic which works on the nervous system and corrects some of the chemical imbalances that cause Parkinson's disease.

Quick tips

Sizonorm Forte Tablet is used for the treatment of schizophrenia.
It is better to take Sizonorm Forte Tablet at night as this medicine may produce drowsiness or sleepiness.
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.
If you are due to have an operation or any dental treatment, please tell the doctor carrying out the treatment that you are taking Sizonorm Forte Tablet. This is because Sizonorm Forte Tablet increases the effects of some anesthetics.
Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
Avoid exposure to sunlight or tanning beds. Sizonorm Forte Tablet can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

Safety advice

Alcohol

UNSAFE

Do not drink alcohol while you are taking this medicine. Sizonorm Forte Tablet may cause excessive drowsiness when taken with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Sizonorm Forte Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Sizonorm Forte Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Sizonorm Forte Tablet may cause side effects that could affect your ability to drive.
Sizonorm Forte Tablet can cause blurring of vision, dizziness, mild nausea, and mental confusion in some cases. This may affect your ability to drive.

Kidney

CAUTION

Sizonorm Forte Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Sizonorm Forte Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Frequently asked questions

What is Sizonorm Forte Tablet used for?

Sizonorm Forte Tablet is used to treat schizophrenia. This medicine helps calm the brain by reducing excessive nerve activity and blocking certain chemical messengers that influence mood and thinking.

Can I expect to feel better right away after taking Sizonorm Forte Tablet?

The exact time Sizonorm Forte Tablet takes to make you feel better is not known. However, you may experience a calming and sedative effect about one hour after taking it, which can help reduce severe anxiety rapidly. The full effects of the medicine on mood and thought patterns may take longer to become noticeable as your body adjusts.

Will I need to take Sizonorm Forte Tablet for a long time?

Sizonorm Forte Tablet is often intended for short-term management of symptoms. Your doctor will determine the right length of treatment for you and will monitor your progress to decide how long you need to take it.

Is it dangerous to stop taking Sizonorm Forte Tablet suddenly?

Yes. You should never stop taking Sizonorm Forte Tablet abruptly without talking to your doctor first. Suddenly stopping the medicine can lead to withdrawal symptoms. Your doctor will guide you on how to taper off the dose safely if it is time to discontinue it.

What important health conditions should I discuss with my doctor before starting Sizonorm Forte Tablet?

Before starting Sizonorm Forte Tablet treatment, it is very important to tell your doctor if you have a history of severe liver or kidney problems, cardiovascular disease, or a type of glaucoma called narrow-angle glaucoma. This information is crucial for your doctor to determine if the medicine is safe for you.

Can Sizonorm Forte Tablet be used to help with alcohol withdrawal?

The chlordiazepoxide component in Sizonorm Forte Tablet on its own is indicated for managing the symptoms of acute alcohol withdrawal. When it is combined with trifluoperazine, as in Sizonorm Forte Tablet, its use is more focused on treating psychiatric conditions such as schizophrenia.

Fact Box

Habit Forming

Yes

Therapeutic Class

NEURO CNS

References

User feedback

What are you using Sizonorm Forte Tablet for?

Schizophrenia

100%

How much was the improvement?

Excellent

83%

Average

17%

What were the side-effects while using Sizonorm Forte Tablet?

No Side Effect

100%

How do you take Sizonorm Forte Tablet?

With food

100%

Please rate Sizonorm Forte Tablet on price

Expensive

100%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Crescent Therapeutics Ltd
Address: SCO-58, 59, Sector-17D Chandigarh-160017

Vendor Details

Country of origin: India

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Why we need a prescription?

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Conventional Antipsychotics

Sizonorm Forte Tablet

Sizonorm Forte Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Sizonorm Forte Tablet

Benefits of Sizonorm Forte Tablet

Side effects of Sizonorm Forte Tablet

How to use Sizonorm Forte Tablet

How Sizonorm Forte Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Sizonorm Forte Tablet used for?

Can I expect to feel better right away after taking Sizonorm Forte Tablet?

Will I need to take Sizonorm Forte Tablet for a long time?

Is it dangerous to stop taking Sizonorm Forte Tablet suddenly?

What important health conditions should I discuss with my doctor before starting Sizonorm Forte Tablet?

Can Sizonorm Forte Tablet be used to help with alcohol withdrawal?

Fact Box

Habit Forming

Therapeutic Class

References

User feedback

What are you using Sizonorm Forte Tablet for?

How much was the improvement?

What were the side-effects while using Sizonorm Forte Tablet?

How do you take Sizonorm Forte Tablet?

Please rate Sizonorm Forte Tablet on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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