Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sizonorm Forte Tablet may be taken with or without food, but it is better to take it at a fixed time. Take it with food, if it causes stomach upset.
Sizonorm Forte Tablet is a combination of three medicines: Chlordiazepoxide, Trifluoperazine and Trihexyphenidyl. Chlordiazepoxide is a benzodiazepine (BZD) which works by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in the brain. Trifluoperazine is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood. Trihexyphenidyl is an anticholinergic which works on the nervous system and corrects some of the chemical imbalances that cause Parkinson's disease.
Sizonorm Forte Tablet may cause excessive drowsiness and calmness with alcohol.
WEIGH RISKS VS BENEFITS
Sizonorm Forte Tablet is unsafe to use during pregnancy. There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Sizonorm Forte Tablet is probably unsafe to use during lactation.
Limited human data suggest that the drug could represent a significant risk to the baby.
Do not drive unless you are feeling well. Sizonorm Forte Tablet can cause blurring of vision, dizziness, mild nausea, and mental confusion in some cases. This may affect your ability to drive.
Sizonorm Forte Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Sizonorm Forte Tablet may be needed. Please consult your doctor.
Sizonorm Forte Tablet should be used with caution in patients with liver disease. Dose adjustment of Sizonorm Forte Tablet may be needed. Please consult your doctor.