Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg )
Prescription Required
Animal use onlyYour pet's medicine at a glance
Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg ) is a medicine used in dogs for the treatment and prevention of parasitic infections, including fleas, ticks, mites, roundworms, hookworms, and heartworm disease. It protects against both external and internal parasites, helping to keep your dog healthy, active, and parasite-free.
Give Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg ) in the dose and duration prescribed by the veterinarian. It can be given with or without food. Ensure your dog swallows the entire portion for complete protection. To maintain continuous effectiveness, administer the medicine on the same date every month. For best results, treat all pets in your household to control fleas and prevent reinfestation, and maintain clean bedding and living areas.
Common side effects of Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg ) include mild digestive issues such as vomiting, diarrhea, or reduced appetite, which are usually temporary. Occasionally, pets may show signs of lethargy or restlessness. These effects typically resolve without treatment, but if symptoms persist or worsen, contact your veterinarian.
Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg ) is meant for dogs only and should not be used on other animals. It should not be given to puppies younger than eight weeks. The product’s safety has not been established in breeding, pregnant, or lactating dogs, so its use in such cases is not recommended unless advised by a veterinarian. Use with caution in dogs with a history of seizures or neurological disorders. Before starting treatment, ensure your dog is tested for heartworm, as the medicine is not effective against adult heartworms.
Uses of Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg ) in pets
- Treatment and prevention of Parasitic infections
Benefits of Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg ) for your pet
In Treatment and prevention of Parasitic infections
Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg ) provides protection against a wide range of parasitic infections that can harm your dog’s health and well-being. It kills and controls external parasites such as fleas, ticks, and mites, helping relieve itching and skin irritation while preventing flea allergy dermatitis. At the same time, it prevents heartworm disease and treats intestinal worms like roundworms and hookworms, which can cause digestive issues and poor growth. When used as prescribed, Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg ) keeps your dog healthier, more energetic, and free from the discomfort and risks caused by parasites.
Side effects of Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg ) in pets
Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg ) does not pose serious side effects and is well-tolerated by pets. In case the side effects do occur, they're likely to subside once the body adapts to the medicine. Consult your pet's veterinarian if these side effects persist or bother your pet. The most common side effects include-
Common side effects of Simparica
- Vomiting
- Diarrhea
- Lethargy
- Decreased appetite
How can I give Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg ) to my pet?
Give the medicine in the dose and duration advised by the veterinarian. It can be given directly to your dog or mixed with a small amount of food to ensure the entire dose is consumed.
How Simparica Chewable Tablet works
Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg ) is a combination of three medicines that work together to eliminate and prevent a broad range of parasites. Sarolaner targets fleas, ticks, and mites by blocking specific nerve channels in their nervous system, causing overexcitation, paralysis, and death. Moxidectin interferes with nerve transmission in heartworms and other internal parasites, leading to their paralysis and elimination. Pyrantel embonate acts on intestinal worms by overstimulating their muscle activity, which results in spastic paralysis and expulsion from the body. Together, these actions protect dogs from internal and external parasitic infections with a single monthly dose.
Safety advice
Pregnancy
The safety of Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg ) has not been established in pregnant dogs. Use during pregnancy is not recommended unless specifically advised by a veterinarian.
Breast feeding
The safety of Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg ) in lactating dogs has not been evaluated. It should be used with caution and only if prescribed by a veterinarian.
Kidney
There is limited data available on the use of Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg ) in dogs with kidney disease. Please consult your veterinarian.
Liver
There is limited data available on the use of Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg ) in dogs with liver disease. Please consult your veterinarian.
What if I forget to give Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg ) to my pet?
If you miss giving a dose of Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg ), administer it as soon as you remember and then continue the regular schedule. Do not give two doses at once to make up for the missed one.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg ) can be given directly or after mixing it with food.
- Ensure your dog swallows the entire portion; if your pet spits it out, offer it again until fully consumed.
- Test your dog for heartworm before starting treatment, as the medicine prevents new infections but does not treat existing ones.
- Clean your dog’s bedding, collars, and living areas regularly to help prevent reinfestation.
- Consult your veterinarian if your dog has a history of seizures or if you notice any unusual signs after giving the medicine.
Fact Box
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
FAQs
What is Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg ) used for in dogs?
Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg ) is a medicine used to protect dogs against multiple parasites. It kills fleas, ticks, and mites, prevents heartworm disease, and treats and controls intestinal worms such as roundworms and hookworms.
How often should I give Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg ) to my dog?
Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg ) should be given once a month, ideally on the same date each month, to ensure continuous protection against both internal and external parasites.
How should I give Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg )?
Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg ) can be given with or without food. Most dogs take it willingly like a treat. Make sure your dog swallows the entire portion to get the full benefit.
Do I need to test my dog before starting Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg )?
Yes. Dogs should be tested for existing heartworm infections before starting Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg ), as the medicine prevents new infections but does not treat adult heartworms.
Can Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg ) be used in puppies?
Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg ) can be given to puppies aged 8 weeks or older and weighing at least 1.25 kg. Consult your veterinarian to ensure the correct dosage based on your puppy’s weight.
Is Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg ) safe for pregnant or lactating dogs?
The safety of Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg ) has not been established in pregnant or lactating dogs. It should be used only if prescribed by a veterinarian after evaluating the risks and benefits.
What should I do to prevent reinfestation after giving Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg )?
Along with regular monthly dosing, clean your dog’s bedding, toys, and living areas frequently. Treat all dogs in the household to ensure full parasite control and prevent reinfestation.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Sarolaner+Moxidectin+Pyrantel Embonate [Prescribing Information]. Kakamazoo, MI: Zoetis Inc.; 2024. [Accessed 08 Nov. 2025] (online) Available from:
- Sarolaner+Moxidectin+Pyrantel Embonate [Prescribing Information]. Kakamazoo, MI: Zoetis Inc.; 2024. [Accessed 08 Nov. 2025] (online) Available from:
Marketer details
Name: Zoetis India Limited
Address: 31, 3Rd Floor, Kalpataru Synergy, Opp. : Grand Hyatt, Santacruz(E) Mumbai Mumbai City Mh 400055 In / Godown No. 1 & 2, Bldg. No 12B, Prithvi Complex, Reti Bunder Road, Kalbar, Tah Bhiwandi -421302, Dist. Thane
Country of origin: Germany
Expires on or after: January, 2027
A licensed vendor partner from your nearest location will deliver Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg ). Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: January, 2027
A licensed vendor partner from your nearest location will deliver Simparica Trio Pet Chewable Tick & Flea Tablet (For >20-40 kg ). Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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MRP₹2415 10% OFF
₹2174
Inclusive of all taxes
3.0 Chewable Tablets in 1 strip
New GST benefit included in this MRP, may differ from label
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