Sigrima 420mg Injection
Prescription RequiredProduct introduction
Sigrima 420mg Injection is used to treat breast cancer. It belongs to group of medicine called monoclonal antibodies.
Sigrima 420mg Injection is given as an injection into veins under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Hair loss, diarrhea, nausea, and fatigue are some common side effects of this medicine. This medicine may reduce the number of blood cells (decrease white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with the heart, liver, and kidney.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Sigrima Injection
Benefits of Sigrima Injection
In Breast cancer
Breast cancer is a disease in which cells in the breast grow uncontrollably, potentially spreading to nearby tissues or other parts of the body. Sigrima 420mg Injection is used along with other cancer medicines to slow or stop the growth of cancer cells, shrink tumors, and help improve survival outcomes in people with certain types of breast cancer.
Side effects of Sigrima Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Sigrima
- Hair loss
- Feeling sick
- Rash
- Stomach inflammation
- Decreased blood cells (red cells, white cells, and platelets)
- Muscle pain
- Cough
- Heartburn
- Breathlessness
- Dizziness
- Fatigue
- Diarrhea
How to use Sigrima Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Sigrima Injection works
Sigrima 420mg Injection is a monoclonal antibody designed to recognize and attach to specific proteins on the surface of cancer cells. Sigrima 420mg Injection gets attached to human epidermal growth factor receptor 2( HER2) and may kill or stop the growth of cancer cells.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Sigrima 420mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Sigrima 420mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Sigrima 420mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Sigrima 420mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Sigrima 420mg Injection is safe to use in patients with kidney disease. No dose adjustment of Sigrima 420mg Injection is recommended.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Sigrima 420mg Injection in patients with liver disease. Please consult your doctor.
What if you forget to take Sigrima Injection?
If you miss a dose of Sigrima 420mg Injection, please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Sigrima 420mg Injection is used in combination with other medicines for the treatment of breast cancer.
- Do not receive any kind of immunization or vaccination without your doctor’s approval while taking Sigrima 420mg Injection.
- Use contraceptives, and do not conceive a child (get pregnant) while taking Sigrima 420mg Injection. Barrier methods of contraception, such as condoms should be used during therapy and for 6 months after treatment.
- Drink at least two to three quarts of fluid every 24 hours, unless you are instructed otherwise.
- You may be at risk of infection so try to avoid crowds or people with colds, and report fever or any other signs of infection immediately to your health care provider.
- To reduce nausea, take anti-nausea medications as prescribed by your doctor, and eat small, frequent meals.
- Take anti-diarrhea medication as prescribed by your doctor and eat foods that may help control diarrhea.
- Avoid sun exposure. Wear SPF 15 (or higher) sunblock and protective clothing.
- Inform your doctor if you are pregnant or breastfeeding before taking Sigrima 420mg Injection.
Fact Box
Chemical Class
Monoclonal antibody (mAb)
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Anti-HER2 Monoclonal Antibody
Interaction with drugs
Taking Sigrima with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not use Pertuzumab with Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted).
Concurrent use may increase the risk of infections.
Do not use Pertuzumab with Cholera Vaccine (Inactivated).
Concurrent use may increase the risk of infections.
Do not use Pertuzumab with Purified Vi Polysaccharide Typhoid Vaccine.
Concurrent use may increase the risk of infections.
Patient concerns
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1095.
- Pertuzumab [FDA Label]. South San Francisco, CA: Genentech, Inc.; 2012. [Accessed 05 Feb. 2020] (online) Available from:
Marketer details
Name: Zydus Lifesciences Ltd
Address: Zydus Corporate Park, 4Th Floor, B Wing, Plot No 103, Near Nirma University,S G Highway, Ahmedabad, 382481
Country of origin: India
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₹66738
Inclusive of all taxes
MRP₹74995 11% OFF
14.0 ml in 1 vial
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