Overview
Uses and benefits
Side effects
How to use
How drug works
Safety advice
Missed dose
All substitutes
Quick tips
Fact box
Patient concerns
User feedback

Author Details

Written By

Dr. Sakshi Jain

MS, BDS

Reviewed By

Dr. Lalit Kanodia

MBA, MD Pharmacology

Last updated

29 Aug 2025 | 01:09 AM (IST)

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Serenace Injection 1ml

Prescription Required

Marketer

RPG Life Sciences Ltd

SALT COMPOSITION

Haloperidol Decanoate (5mg)

Storage

Store below 25°C

Click here to view all substitutes

Product introduction

Serenace Injection 1ml is used in the treatment of schizophrenia. It is also used to treat psychosis, mania, severe behavior problems, and Tourette syndrome (chronic multiple motor and vocal problems and involuntary responses) in adults and children.

Serenace Injection 1ml works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood. It is given under the supervision of a healthcare professional only. Use it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember. Do not stop suddenly without talking to the doctor, as it may worsen your symptoms. The doctor may check heart function and level of electrolytes such as sodium and magnesium before you start treatment with this medicine and regularly thereafter. Take plenty of fluids while taking this medicine as it may also cause dehydration.

Some common side effects of this medicine include injection site reactions (pain, swelling, redness), dryness in the mouth, urinary retention, constipation, and tremor. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, rise slowly if you have been sitting or lying down. It also causes dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. Additionally, this medicine can lead to weight gain, eat a healthy balanced diet, and exercise regularly.

Uses of Serenace Injection

Schizophrenia

Benefits of Serenace Injection

In Schizophrenia

Schizophrenia is a mental disorder in which a person’s thinking ability, feelings and behavior become abnormal. Serenace Injection 1ml helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life.

Side effects of Serenace Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Serenace

Abnormality of voluntary movements
Constipation
Dryness in mouth
Increased prolactin level in blood
Muscle stiffness
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Sleepiness
Tremors
Urinary retention
Weight gain

How to use Serenace Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Serenace Injection works

Serenace Injection 1ml is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Serenace Injection 1ml.

Pregnancy

CONSULT YOUR DOCTOR

Serenace Injection 1ml may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Serenace Injection 1ml is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Serenace Injection 1ml may cause side effects which could affect your ability to drive.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Serenace Injection 1ml in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Serenace Injection 1ml in patients with liver disease. Please consult your doctor.

What if you forget to take Serenace Injection?

If you miss a dose of Serenace Injection 1ml, please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Serenace Injection 1ml

₹6.9/Injection

Trancodol 5mg Injection

Intas Pharmaceuticals Ltd

₹6.51/injection

11% cheaper

Mindol 5mg Injection

Micron Biotech

₹4.5/injection

38% cheaper

Sydol 5mg Injection

SPM Drugs Pvt Ltd

₹115.5/injection

1487% costlier

Halow Injection

Sigmund Promedica

₹8.52/injection

17% costlier

Quick tips

Use caution while driving or doing anything that requires concentration as Serenace Injection 1ml may cause dizziness and sleepiness.
Avoid drinking alcohol while taking this medicine as it can cause increased dizziness.
It may affect how your body regulates your temperature. Avoid getting dehydrated and drink plenty of fluids.
Inform your doctor if you experience any abnormal movements or have difficulty controlling movements.
Inform your doctor if you experience symptoms such as high fever, sweating, muscle stiffness, and faster breathing. These may be due to a rare side effect known as the neuroleptic malignant syndrome.
Your doctor may check your heart function and level of electrolytes such as sodium and magnesium before you start treatment with this medicine and regularly thereafter.
Do not stop taking Serenace Injection 1ml without talking to your doctor first as it may cause worsening of symptoms.

Fact Box

Chemical Class

Alkyl-phenylketone derivatives

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Typical Antipsychotics

Patient concerns

My daughter has been diagnosed for conversion disorder She was showing the symptomps such as fits , one incidence of memory loss ,vision lost, not able to speak once .Doctor in bhopal has prescribed her Serence 1.5 Pacitane Clonofit.25 thrice a day and lopez 1 mg at night.kindly guide me is all going right

Dr. Jyoti Kapoor Madan

Psychiatry

Conversion Reactions are primarily due to anxiety. A child is unable to express the anxiety and symptoms are converted to physical symptoms. Treatment largely depends upon exploring the cause of anxiety, training the child to deal with it and antidepressants. Psychotherapy is very important. Serenace is an antipsychotic usually prescribed for psychotic symptoms.

unwanted noises in ears coming and i am seeing some hallucination in left eyes i am taking clorpam 1mg - half tablet daily once during night, serenace 1.5 mg and pacitane 2 mg daily once during night, telminorm 40mg - 1 tablet every night for blood pressure, statix - f - tablet 1 every night

Dr. Jyoti Kapoor Madan

Psychiatry

Your symptoms are suggestive of auditory hallucinations which may be due to a psychotic disorder. It requires regular medication and treatment.

suffering from schizophrenia plz help

Dr. Jyoti Kapoor Madan

Psychiatry

Schizophrenia is a chronic problem caused by Neuro chemical disturbance in brain. It is characterised by fear, odd experiences and distorted thought pattern. Treatment is with antipsychotic medicines which may need to continue throughout life. Coping with a mental disorder as serious as schizophrenia can be challenging, both for the person with the condition and for friends and family. Here are some ways to cope: 1. Learn about schizophrenia. Education about the disorder can help motivate the person with the disease to stick to the treatment plan. Education can help friends and family understand the disorder and be more compassionate with the person who has it. 2. Join a support group. Support groups for people with schizophrenia can help them reach out to others facing similar challenges. Support groups may also help family and friends cope. 3. Stay focused on goals. Managing schizophrenia is an ongoing process. Keeping treatment goals in mind can help the person with schizophrenia stay motivated. Help your loved one remember to take responsibility for managing the illness and working toward goals. 4. Ask about social services assistance. These services may be able to assist with affordable counselling services, job placements and other daily activities. 5. Learn relaxation and stress management. The person with schizophrenia and loved ones may benefit from stress-reduction techniques such as meditation, yoga or tai chi. Please see a psychiatrist for further guidance.

User feedback

Patients taking Serenace Injection 1ml

Once A Month

34%

Once A Day

33%

Once A Week

15%

Twice A Day

10%

Twice A Month

Twice A Week

Alternate Day

What are you using Serenace Injection for?

Schizophrenia

55%

Others

45%

How much was the improvement?

Average

39%

Excellent

39%

Poor

22%

What were the side-effects while using Serenace Injection 1ml?

Sleepiness

33%

Dryness in mo*

22%

Orthostatic h*

22%

Weight gain

22%

*Dryness in mouth, Orthostatic hypotension (sudden lowering of blood pressure on standing)

How do you take Serenace Injection?

With or witho*

67%

With food

33%

*With or without food

Please rate Serenace Injection 1ml on price

Not Expensive

50%

Expensive

33%

Average

17%

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Haloperidol Decanoate. High Wycombe, Buckinghamshire: Janssen-Cilag Ltd.; 1982 [revised 6 Jun. 2017]. [Accessed 25 Mar. 2019] (online) Available from:
PubChem. Haloperidol Decanoate. [Accessed 25 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:

Marketer details

Name: RPG Life Sciences Ltd

Address: 463, 4 th Floor, RPG HOUSE, Dr. Annie Besant Road, Worli, Mumbai – 400 030. Maharashtra, INDIA

Country of origin: India
Expires on or after: November, 2026

A licensed vendor partner from your nearest location will deliver Serenace Injection 1ml. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India