Overview
Uses and benefits
Side effects
How to use
How drug works
Safety advice
Missed dose
All substitutes
Quick tips
Fact box
Patient concerns
FAQs

Author Details

Written By

Dr. Lipika Khurana

PGDHHM, BDS

Reviewed By

Dr. Mekhala Chandra

MD, MBBS

Last updated

19 Nov 2025 | 10:19 PM (IST)

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Ribziff OXT Tablet

Prescription Required

Marketer

Cafoli Lifecare Pvt. Ltd.

SALT COMPOSITION

Ondansetron (4mg) + Rabeprazole (20mg)

Storage

Store below 25°C

31% cheaper alternative available with same salt composition

Click here to view all substitutes

Product introduction

Ribziff OXT Tablet is a combinational medicine commonly used to control nausea and vomiting due to certain medical conditions like stomach upset. It is also used to treat heartburn, acid reflux and problems in your food pipe.

Ribziff OXT Tablet can be taken with or without food. How much you need, and how often you take it, will depend on what you are being treated for. Follow the advice of your doctor. You should keep taking it regularly to prevent problems from happening in the future. You may be able to help improve your symptoms by eating smaller meals more often and avoiding spicy or fatty foods.

Most people who take it do not have any side effects, but the most common include headache, constipation and diarrhea. If you do get a side effect, it is usually mild and will go away when you stop taking this medicine or as you adjust to it. Consult your doctor if any of these side effects bother you or do not go away.

Before taking it, you should tell your doctor if you have any kidney or liver problems. This may affect the dose or suitability of this medicine. Also, tell your doctor what other medicines you are taking as some may affect, or be affected by, this medicine. If you are pregnant or breastfeeding, ask advice from your doctor.

Uses of Ribziff OXT Tablet

Benefits of Ribziff OXT Tablet

In Nausea

Ribziff OXT Tablet blocks the action of chemicals in the body that can make you feel or be sick. This medicine helps you feel better and at ease. It is given as an injection by a doctor and you should follow the doctor’s instructions carefully to get the most benefit from this medicine.

In Gastroesophageal reflux disease (Acid reflux)

Gastroesophageal reflux disease (GERD) is a chronic (long-term) condition which is like having heartburn consistently rather than just occasionally. It happens because a muscle above your stomach relaxes too much and allows stomach contents to come back up into your esophagus and mouth. Ribziff OXT Tablet reduces the amount of acid your stomach makes and relieves the pain associated with heartburn and acid reflux. You should take it exactly as it is prescribed for it to be effective.

Some simple lifestyle changes can help reduce the symptoms of GERD. Think about what foods trigger heartburn and try to avoid them; eat smaller, more frequent meals; try to lose weight if you are overweight and try to find ways to relax. Do not eat within 3-4 hours of going to bed.

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Side effects of Ribziff OXT Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ribziff OXT

Nausea
Vomiting
Pain
Sore throat
Infection
Abdominal pain
Headache
Constipation
Fatigue
Diarrhea

How to use Ribziff OXT Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ribziff OXT Tablet may be taken with or without food.

How Ribziff OXT Tablet works

Ribziff OXT Tablet is a combination of two medicines: Ondansetron and Rabeprazole. Ondansetron is an antiemetic medication. It works by blocking the action of a chemical messenger (serotonin) in the brain that may cause nausea and vomiting. Rabeprazole is a proton pump inhibitor (PPI) which works by reducing the amount of acid in the stomach which helps in the relief of acid-related indigestion and heartburn.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Ribziff OXT Tablet

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of Ribziff OXT Tablet during pregnancy is not available. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Ribziff OXT Tablet during breastfeeding is not available. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Ribziff OXT Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Ribziff OXT Tablet in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Ribziff OXT Tablet in patients with liver disease.

What if you forget to take Ribziff OXT Tablet?

If you miss a dose of Ribziff OXT Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Ribziff OXT Tablet

₹8.36/Tablet

Rebozen ON 4mg/20mg Tablet

Leeford Healthcare Ltd

₹5.81/tablet

31% cheaper

Rafron Total Tablet

Saffron Formulations Pvt Ltd

₹15/tablet

79% costlier

Rypraz O 4mg/20mg Tablet

Arlak Biotech Pvt Ltd

₹7.18/tablet

14% cheaper

Rowet OD 4mg/20mg Tablet

Aden Healthcare

₹6.26/tablet

25% cheaper

Rabopep O Tablet

Seagull Pharmaceutical Pvt Ltd

₹5.23/tablet

37% cheaper

Quick tips

Ribziff OXT Tablet is used to give relief from nausea, vomiting as well as acidity, heartburn and other discomfort associated with acid reflux and peptic ulcer disease.
It is advisable to take your doses about half an hour before meals.
If you vomit within one hour of taking a dose, take another dose.
Avoid taking soft drinks, citrus fruits like orange and lemon, which can irritate the stomach and increase acid secretion.
Incorporate the following lifestyle changes in order to prevent acidity:
1. Make sure you eat regular meals and drink plenty of water.
2. Avoid spicy and fatty fried food.
3. Lose weight if you are obese.
4. If you are a smoker, consider giving up.
5. Don't drink too much alcohol.
6. Do not go to bed immediately after taking a meal. Sit in a relaxed position for sometimes for better digestion.

Fact Box

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Patient concerns

Gastric nausea vomiting reflux

Dr. Pushkar Mani

Physician

sompraz D 40 mg twice daily 1 hour before meal for 10 days

acid reflux, gastric, sugar stimulate acid reflux.

Dr. Pushkar Mani

Physician

CBC,ESR,LIPID PROFILE,URINE RE/CS, KFT, LFT, VIT D & B estimation,TAKE RABEKIND DSR once a day empty stomach FOR 3 week

Heartburn Mental disorder Depression Frequent persistent heartburn Gastroesophageal reflux disease Irritable bowel syndrome Indigestion Back flow of acid from stomach Difficulty in swallowing Inflammation of esophagus Excess acid secretion by stomach Intestinal or stomach ulcers

Dr. Sunil Sekhri

Diabetology

You need to be examined in clinic to reach a diagnosis and then appropriate medicine can be prescribed

What is Ribziff OXT Tablet used for?

Ribziff OXT Tablet is used to relieve nausea and vomiting caused by conditions such as an upset stomach. It is also helpful in treating heartburn, acid reflux, and other problems related to the food pipe (esophagus).

Is Ribziff OXT Tablet used for GERD or ulcers when I also feel queasy or vomit?

Yes, Ribziff OXT Tablet supports reflux/ulcer care while also calming nausea, which can make it easier to keep food and medicines in stomach and not vomit out.

I get morning heartburn and feel sick after meals. Can Ribziff OXT Tablet help?

Many patients take Ribziff OXT Tablet when reflux‑related nausea is worst around meals. Your doctor will tailor the timing and duration of your routine.

Will Ribziff OXT Tablet help protect my stomach while I am on other treatments that upset it?

Ribziff OXT Tablet is commonly used when treatments irritate the stomach, combining nausea relief with acid reduction to improve comfort and adherence.

How soon might day‑to‑day symptoms start improving during Ribziff OXT Tablet treatment?

People often notice a calmer stomach and reduced queasiness within a day or two of using Ribziff OXT Tablet. Full benefit for reflux/ulcer symptoms builds over days to weeks as your plan continues.

Can I keep using my usual reflux lifestyle steps with Ribziff OXT Tablet?

Yes. Small regular meals, avoiding trigger foods, and elevating the head of the bed complement the Ribziff OXT Tablet and often improve results further.

What if my nausea or heartburn does not settle after a couple of weeks of using Ribziff OXT Tablet?

If your nausea or heartburn doesn’t improve after using Ribziff OXT Tablet for a couple of weeks, inform your doctor. Share details such as when the symptoms occur, what triggers them, and how severe they are. Your doctor may adjust the dose or timing of your medicine, or check for other possible causes like infection, bile reflux, or side effects from other medications.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Sharkey KA, MacNaughton WK. Gastrointestinal Motility and Water Flux, Emesis, and Biliary and Pancreatic Disease. In: Brunton LL, Hilal-Dandan R, Knollmann BC (Editors). Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 13th ed. New York, NY: McGraw-Hill Education; 2018. pp. 922-944.
Hoogerwerf WA, Pasricha PJ. Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 967-981.
McQuaid KR. Drugs Used in the Treatment of Gastrointestinal Diseases. In: Katzung BG, Masters SB, Trevor AJ (Editors). Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 1067-1101.
Rabeprazole and ondansetron. Pune, Maharashtra: Epione Pharmaceuticals Pvt. Ltd.; [Accessed 05/11/2025] (online) Available from:

Marketer details

Name: Cafoli Lifecare Pvt. Ltd.

Address: Plot no.: 367-FF, Industrial Area Phase-I,Panchkula-134113

Country of origin: India
Expires on or after: February, 2026

A licensed vendor partner from your nearest location will deliver Ribziff OXT Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India