Pyrevay-SP Tablet is a combination medicine that helps in relieving pain. It works by blocking the release of certain chemical messengers that cause pain, inflammation, and fever in various conditions. It also promotes healing at the site of inflammation.
Pyrevay-SP Tablet should be taken with food. This will prevent you from getting an upset stomach. The dose will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for a longer duration than recommended by the doctor.
The most common side effects of this medicine include nausea, vomiting, diarrhea, stomach pain, increased liver enzymes, and heartburn. If any of these side effects bother you or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the side effects.
Before taking it, you should let your doctor know if you have a history of ulcer or bleeding in your stomach, high blood pressure, or have any trouble with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.
Pregnant or breastfeeding women should consult their doctor before starting treatment. You should also avoid drinking alcohol while you are taking this medicine, as alcohol can cause excessive drowsiness.
Note: As per the Ministry of Health and Family Welfare, Pyrevay-SP Tablet is banned for children under 12 years of age.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pyrevay-SP
Nausea
Vomiting
Diarrhea
Stomach pain
Increased liver enzymes
Heartburn
How to use Pyrevay-SP Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pyrevay-SP Tablet is to be taken with food.
How Pyrevay-SP Tablet works
Pyrevay-SP Tablet is a combination of three medicines: Nimesulide, Paracetamol and Serratiopeptidase. Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) and Paracetamol is an antipyretic (fever reducer). They work by blocking the release of certain chemical messengers in the brain that cause pain and fever. Serratiopeptidase is an enzyme which works by breaking down abnormal proteins at the site of inflammation, and promotes healing.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Pyrevay-SP Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Pyrevay-SP Tablet during pregnancy is not available. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Pyrevay-SP Tablet during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Pyrevay-SP Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CAUTION
Pyrevay-SP Tablet should be used with caution in patients with kidney disease. Dose adjustment of Pyrevay-SP Tablet may be needed. Please consult your doctor. Use of Pyrevay-SP Tablet is not recommended in patients with severe kidney disease.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Pyrevay-SP Tablet in patients with liver disease. Please consult your doctor.
What if you forget to take Pyrevay-SP Tablet?
If you miss a dose of Pyrevay-SP Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Few days back there was symptoms of chikunguniya observed approx 20 days back,now there's no fever and other problems but joint pains is causing much discomfort,please suggest on this. Thanks
Dr. Akshat Goel
Orthopaedics
Apply Dynapar QPS spray and take Tab Zerodol-SP twice daily for pain relief
Can I stop taking Pyrevay-SP Tablet when my pain is relieved?
Pyrevay-SP Tablet is usually used for short-term pain relief and can be discontinued if there is no pain. However, it should be continued if advised by the doctor.
Can the use of Pyrevay-SP Tablet cause damage to the liver?
Pyrevay-SP Tablet contains nimesulide and paracetamol, and both these medicines are known to cause harm to the liver especially in doses above the recommended level. Also, avoid drinking alcohol while taking this medicine, as it may further increase your risk of liver damage. Use of this medicine should preferably be avoided in patients with underlying liver disease.
Can I take a higher than the recommended dose of Pyrevay-SP Tablet?
No, taking a higher than the recommended dose of Pyrevay-SP Tablet can lead to increased chances of side effects. If the recommended dosage does not relieve your symptoms or you experience increased severity of pain, please consult your doctor for re-evaluation.
What are the instructions for the storage and disposal of Pyrevay-SP Tablet?
Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
European Medicine Agency. Nimesulide; 2004. [Accessed 02 Apr. 2019] (online) Available from:
Bhagat S, Agarwal M, Roy V. Serratiopeptidase: A systematic review of the existing evidence. Int J Surg. 2013;11(3):209-17. [Accessed 02 Apr. 2019] (online) Available from:
ScienceDirect. Nimesulide. [Accessed 02 Apr. 2019] (online) Available from:
ScienceDirect. Paracetamol. [Accessed 02 Apr. 2019] (online) Available from:
PubChem. Serratiopeptidase. [Accessed 02 Apr. 2019] (online) Available from:
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.