Overview
Uses and benefits
Side effects
How to use
How drug works
Safety advice
Missed dose
All substitutes
Quick tips
Fact box
Patient concerns
FAQs

Author Details

Written By

Dr. Lipika Khurana

PGDHHM, BDS

Reviewed By

Dr. Rajeev Sharma

MBA, MBBS

Last updated

19 Sep 2025 | 03:30 PM (IST)

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Home>Potentox>potentox 250 mg/1000 mg injection

Potentox 250 mg/1000 mg Injection

Prescription Required

Marketer

Venus Remedies Ltd

SALT COMPOSITION

Amikacin (250mg) + Cefepime (1000mg)

Storage

Store below 30°C

View available alternative with same salt composition

Click here to view all substitutes

Product introduction

Potentox 250 mg/1000 mg Injection is a combination of two antibiotics prescribed to treat various types of bacterial infections. It fights against the infection by inhibiting the growth of the microorganisms to prevent further infections.

Potentox 250 mg/1000 mg Injection is a combination of two medicines: Potentox 250 mg/1000 mg Injection1 and Potentox 250 mg/1000 mg Injection2.

Uses of Potentox Injection

Treatment of Bacterial infections

Benefits of Potentox Injection

In Treatment of Bacterial infections

Potentox 250 mg/1000 mg Injection kills the bacteria that can cause serious infections. It usually makes you feel better very quickly, but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and you do not become resistant.

Side effects of Potentox Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Potentox

Injection site reaction
Diarrhea
Nausea
Injection site phlebitis
Myoclonic encephalopathy
Seizure
Cochlear damage
Balance disorder (loss of balance)
Muscle paralysis
Apnea (absence of breathing)
Stevens-Johnson syndrome
Erythema multiforme
Toxic epidermal necrolysis
Renal dysfunction
Increased creatinine level in blood
Albumin in urine
Low urine output
Nephropathy toxicity
Aplastic anemia
Hemolytic anemia
Hemorrhage
Cholestasis
Decreased blood cells (red cells, white cells, and platelets)
Injection site reactions (pain, swelling, redness)
Hearing loss
Vomiting

How to use Potentox Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Potentox Injection works

Potentox 250 mg/1000 mg Injection is a combination of two medicines: amikacin and cefepime. Amikacin is an antibiotic which stops bacterial growth by preventing the synthesis of essential proteins required by bacteria to carry out vital functions. Cefepime is also an antibiotic that works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria in the human body. Together, these medications eradicate the bacterial infection effectively.

Safety advice

Alcohol

CAUTION

Caution is advised when consuming alcohol with Potentox 250 mg/1000 mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Potentox 250 mg/1000 mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Potentox 250 mg/1000 mg Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Avoid prolonged use of Potentox 250 mg/1000 mg Injection, since it may have possible effects such as rash and diarrhea.

Driving

UNSAFE

Potentox 250 mg/1000 mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Potentox 250 mg/1000 mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Potentox 250 mg/1000 mg Injection may be needed. Please consult your doctor.

Liver

SAFE IF PRESCRIBED

Potentox 250 mg/1000 mg Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Potentox 250 mg/1000 mg Injection may not be needed in these patients. Please consult your doctor.

What if you forget to take Potentox Injection?

If you miss a dose of Potentox 250 mg/1000 mg Injection, please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Potentox 250 mg/1000 mg Injection

₹319/Injection

Mikapime 250 mg/1000 mg Injection

Alembic Pharmaceuticals Ltd

₹225.34/injection

36% cheaper

Quick tips

Potentox 250 mg/1000 mg Injection is given as an injection into vein or drip under the supervision of a doctor.
Do not skip any doses and finish the full course of the treatment even if you feel better. Stopping it early may cause recurrence of the infection and make it harder to treat.
Your doctor will monitor your kidney function, blood urea level, and hearing capability regularly during the treatment.
During the treatment with this combination medicine, take proper rest to achieve a faster recovery.
Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.

Fact Box

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Patient concerns

Scar on face due to bacterial infections

Dr. Atul Jain

Dermatology

Pic is not clear, plz visit for proper opinion

I have a history of recurring yeast and bacterial vaginosis infections.

Dr. Sonu Balhara Ahlawat

Obstetrics and Gynaecology

Tab metrogyl 500 mg twice a day x 5 days and tab fluconazole 150 mg three doses alternate days

What if I don't get better after using Potentox 250 mg/1000 mg Injection?

Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.

How long does Potentox 250 mg/1000 mg Injection takes to work?

Usually, Potentox 250 mg/1000 mg Injection starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.

Related lab tests

Complete Blood Count

Peripheral Smear Examination

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Venus Remedies Limited. Amikacin + Cefepime. [Accessed 08 Apr. 2019] (online) Available from:
Amikacin sulfate. Hurley, Maidenhead: Hospira UK Limited; 1996 [revised Aug. 2015]. [Accessed 08 Apr. 2019] (online) Available from:
Cefepime. Deerfield, Illinois: Baxter Healthcare Corporation; 1996. [Accessed 08 Apr. 2019] (online) Available from:
Amikacin [Patient Information Sheet]. Port Elizabeth, South Africa: Fresenius Kabi Manufacturing SA (Pty) Ltd.; 2012. [Accessed 10 Oct. 2023] (online) Available from:
Cefepime [Prescribing Information]. Bethlehem, PA: Piramal Critical Care; 2019. [Accessed 08 Apr. 2023] (online) Available from: