Piat 15 mg/10 mg Tablet

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Potentiallyunsafewith
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Alcohol
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46.82
₹4.68/Tablet
10 tablets in 1 strip
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Medicine Overview of Piat 15 mg/10 mg Tablet

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Uses of Pioglitazone

Pioglitazone is used in the treatment of type 2 diabetes.
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Side effects of Pioglitazone

Common

Blurred vision, Respiratory tract infection, Bone fracture, Numbness.

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How to use Pioglitazone

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. It can be taken with or without food, but it is better to take Piat 15 mg/10 mg Tablet at a fixed time.

How Piat 15 mg/10 mg Tablet works

Pioglitazone is an anti-diabetic medicine. It works by increasing the body's sensitivity to insulin, a natural substance that helps control blood sugar levels.
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Uses of Atorvastatin

Atorvastatin is used in the treatment of increased cholesterol levels in blood, increased triglycerides levels in blood and increased LDL levels in blood.
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Side effects of Atorvastatin

Common

Musculoskeletal (bone, muscle or joint) pain, Allergic reaction, Headache, Nausea, Dyspepsia, Nasopharyngitis, Increased liver enzymes, Increased creatine phosphokinase (CPK) level in blood, Diarrhoea, Flatulence, Constipation, Joint swelling, Increased glucose level in blood.

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How to use Atorvastatin

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. It can be taken with or without food, but it is better to take Piat 15 mg/10 mg Tablet at a fixed time.

How Piat 15 mg/10 mg Tablet works

Atorvastatin is a cholesterol-lowering medicine (statins). It works by blocking an enzyme (HMG-CoA-reductase) that is required in the body to make cholesterol. It thus lower "bad" cholesterol (LDL), triglycerides and raise "good" cholesterol (HDL).

In Depth Information on Piat 15 mg/10 mg Tablet

Expert advice for Pioglitazone

  • Highly effective in decreasing haemoglobin A1c level (Hemoglobin A1c measures average blood sugar over time).
  • Pioglitazone may rarely cause hypoglycemia.
  • Pioglitazone is more likely to cause weight gain as compared to other anti-diabetic medicines.
  • Pioglitazone may cause fluid retention (edema), ranging from mild ankle swelling to severe swelling in the lungs that make it hard to breathe.
  • Inform your doctor if you have ever been diagnosed with any heart problems (high blood pressure, heart attack, heart failure, slow or irregular heart rate).
  • Inform your doctor if you have ever been diagnosed with kidney or liver problems.
  • Inform your doctor if you have ever been diagnosed with bladder cancer.

Expert advice for Atorvastatin

  • Inform your doctor if you have muscle pain, cramps, weekness, tiredness or dark coloured urine while taking Atorvastatin.
  • Atorvastatin may increase blood sugar levels. Your doctor may ask to monitor your blood sugar levels regularly.
  • Inform your doctor if you regularly drink a large amount of alcohol.
  • Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
  • Inform your doctor if you have ever been diagnosed with kidney or liver problems.
Warnings
Special precautions for Piat 15 mg/10 mg Tablet
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Alcohol
CAUTION
Taking pioglitazone with alcohol may affect blood glucose levels in patients with diabetes.

Taking Atorvastatin with alcohol may increase the risk of liver damage.
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Pregnancy
CAUTION
Piat 15 mg/10 mg Tablet is highly unsafe to use during pregnancy.

Human and animal studies have shown significant adverse effects on the foetus. Please consult your doctor.
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Lactation
Piat 15 mg/10 mg Tablet is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.

Monitor the breastfed baby’s blood sugar during treatment with Piat 15 mg/10 mg Tablet
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Driving
SAFE
Piat 15 mg/10 mg Tablet does not usually affect your ability to drive.
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Kidney
SAFE
Piat 15 mg/10 mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Piat 15 mg/10 mg Tablet is recommended.

Use of Piat 15 mg/10 mg Tablet is not recommended in patients undergoing dialysis.
However, talk to your doctor if you have any underlying kidney disease.
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Liver
CAUTION
Piat 15 mg/10 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Piat 15 mg/10 mg Tablet may be needed. Please consult your doctor.

Use of Piat 15 mg/10 mg Tablet is not recommended in patients with severe liver disease.
Use of Piat 15 mg/10 mg Tablet is not recommended in patients with severe liver disease and active liver disease.
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Patient Concerns

Frequently asked questions for Piat 15 mg/10 mg Tablet

Frequently asked questions for Pioglitazone

Q. Is Pioglitazone a blood thinner?
No. Pioglitazone is an anti-diabetic medication. Blood thinners are the medicine that prevents the formation of a harmful blood clot. These include medicines like Aspirin, Heparin and Warfarin.
Q. Is Pioglitazone a diuretic?
No. Pioglitazone is not a diuretic. It is used in the treatment of Diabetes Mellitus. Diuretics are those medicine which increases urination.
Q. Can Pioglitazone used in Hepatitis B infection?
Some studies have shown that Pioglitazone may be helpful in preventing Hepatitis B Virus-associated Hepatocellular Cancer (Liver Cancer). However, these findings are still very preliminary and clear role has not been established.
Q. Can Pioglitazone used in Hepatitis C infection?
Pioglitazone has been shown to inhibit Liver Cancer (HCC) recurrence in overweight Hepatitis C Virus-infected diabetic patients. It also improved insulin resistance (a state where the body is resistant to the effects and functions of the insulin hormone) in them.
Q. Can Pioglitazone used along with Vitamin D?
Studies indicate that Vitamin-D combined with Pioglitazone may be more effective in improving Bone Mineral Density and Bone Metabolism than Vitamin-D or Pioglitazone alone in the treatment of Diabetes Mellitus patients with kidney dysfunction (Diabetic Nephropathy).
Q. Can Pioglitazone be used along with sitagliptin?
Combination therapy with Sitagliptin and Pioglitazone leads to a substantial and sustained improvement in glycemic (blood sugar) control compared to the treatment with Pioglitazone alone. This is useful for patients who cannot tolerate Metformin or Sulfonylureas.
Q. Is there any role of Pioglitazone in Alzheimer disease?
Recent evidence suggests that Pioglitazone may be beneficial in Alzheimer's disease (AD), decreasing the cognitive decline early in the disease process. However, larger studies are now in progress to establish the same.
Q. Can Pioglitazone and repaglinide combined in diabetes treatment?
For patients who previously failed oral antidiabetic therapy, the combination of Repaglinide and Pioglitazone have acceptable safety, with greater reductions of glycemic parameters (blood sugar levels) than using either agent alone.
Q. Does Pioglitazone cause urinary bladder tumour?
Large population studies indicate that Pioglitazone is associated with an increased risk of bladder cancer. The absence of an association of bladder cancer with the other drug of the same class, Rosiglitazone, suggests that the increased risk is drug specific and not a class effect.
Q. Are Pioglitazone and rosiglitazone same?
Pioglitazone & Rosiglitazone both belong to a class of antidiabetics called Thiazolidinediones. Rosiglitazone has been removed from the market because using this drug was associated with increased risk of cardiovascular events like heart attack and stroke. This is not seen with Pioglitazone.
Q. Can Pioglitazone be used along with glimepiride in diabetes?
Pioglitazone when added to Glimepiride in Patients with Diabetes Mellitus, has been found to significantly reduce plasma lipid levels and significant improvement in blood pressure control related to a reduction in the insulin resistance.
Q. Is Pioglitazone a steroid?
No. Pioglitazone is not a steroid. It is an anti-diabetic medication which belongs to the class of thiazolidinediones.
Q. How to use Pioglitazone?
Pioglitazone is an anti-diabetes drug used along with a proper diet and exercise program to control high blood sugar in patients with type 2 diabetes. Pioglitazone acts as an insulin sensitizer and decreases the extent of insulin resistance in the body too.
Q. How safe is Pioglitazone?
Pioglitazone cardiovascular safety profile compares favourably with that of Rosiglitazone. Pioglitazone has been found to be associated with bladder tumours but causality assessment has not been proved yet.
Q. How does Pioglitazone cause oedema?
Pioglitazone increases the permeability of fluid in tiny blood vessels called capillaries. This results in easier movement of fluids across the membrane and their consequent accumulation, resulting in oedema (puffiness). Also, Pioglitazone causes increased sodium and water reabsorption from the kidney that contributes to the oedema.
Q. How does Pioglitazone cause bladder cancer?
The mechanism behind the link between Pioglitazone use and bladder cancer is still unknown. Studies have suggested that use of Pioglitazone for more than one year results in increased risk of development of tumour of the urinary bladder.
Q. How does Pioglitazone cause heart failure?
Pioglitazone can cause fluid retention and edema. Consequently, there is a lot of fluid in the body (fluid overload). As a result, it may precipitate heart failure (which worsens with fluid overload in those at risk).
Q. How Pioglitazone protects against atherosclerosis?
Studies in animals have concluded that Pioglitazone improves the elasticity of the aortic wall ( the aorta is a large blood vessel that arises from the heart and supplies oxygenated blood to the rest of the body). This may be a mechanism by which it protects against atherosclerosis, but more studies are needed to confirm this.
Q. Can Pioglitazone be used with insulin?
The addition of Pioglitazone reduces daily insulin dosages, but study findings have not been consistent. Improvement of lipid profiles has also been weak with this combination therapy. Long-term studies are needed before any conclusions can be reached. Combination therapy should be primarily used for patients who achieve an insufficient reduction in blood sugar with insulin alone.
Q. Which is not safe in heart failure, Pioglitazone or rosiglitazone?
Pioglitazone & Rosiglitazone both belong to a class of antidiabetics called Thiazolidinediones. Rosiglitazone has been removed from the market because using this drug was associated with increased risk of cardiovascular events like heart attack and stroke. Pioglitazone can cause heart failure too, but the risk is less that that with Rosiglitazone. Both the medicines should be avoided in heart failure.
Q. What are the alternatives to Pioglitazone?
Fortunately, there are many alternatives to Pioglitazone- Metformin, Acarbose, Sitagliptin, Exenatide, Insulin or combination therapies of these medicines can be used.
Q. Can Pioglitazone used for dementia?
Findings indicate that Pioglitazone treatment is associated with a reduced dementia risk in Diabetes mellitus patients. Prospective studies are needed to evaluate a possible neuroprotective effect in these patients in an ageing population.
Q. Can Pioglitazone used for infertility?
Pioglitazone may be of use in infertile patients with polycystic ovary syndrome (PCOS) who are resistant to conventional ovulation induction such as by drugs like Clomiphene, Dexamethasone, or Metformin.
Q. Can Pioglitazone used for psoriasis?
The use of Pioglitazone for plaque psoriasis treatment is controversial. Some studies revealed no effect of Pioglitazone 30 mg daily neither on the clinical response of moderate-to-severe psoriasis whereas others demonstrate that it could be considered as an efficacious and safe agent for the treatment of plaque psoriasis.
Q. Can Pioglitazone used for autism?
In a research study in a small number of autistic children, daily treatment with 30 or 60 mg Pioglitazone for 3–4 months induced apparent clinical improvement. Pioglitazone should be considered for further testing of therapeutic potential in autistic patients but as of now, autism is not an approved indication for Pioglitazone use.
Q. Can Pioglitazone be used in depression?
Pioglitazone, either alone or as add-on therapy to conventional treatments, could clinically benefit patients of major depression according to a study.
Q. Can Pioglitazone used for weight loss?
A recent study shows that although Pioglitazone causes a significant decrease in blood sugar, HbA1C and lipid levels, it is associated with weight gain, which would limit its utility. It has not been shown to cause weight loss.
Q. Can Pioglitazone be used to treat fatty liver?
Pioglitazone has also been used to treat non-alcoholic steatohepatitis (fatty liver), but this use is presently considered experimental.
Q. Can Pioglitazone be used for secondary stroke prevention?
Pioglitazone reduces recurrent stroke and major vascular events in stroke patients with insulin resistance, prediabetes, and diabetes mellitus. However, its use as a preventive therapy requires more research.
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Frequently asked questions for Atorvastatin

Q. Is Atorvastatin used for lowering cholesterol?
Atorvastatin belongs to a group of medicines known as statins, which are lipid (fat) lowering medicines. It is used to lower lipids known as cholesterol and triglycerides in the blood when a low-fat diet and lifestyle changes on their own have failed. If you are at an increased risk of heart disease, Atorvastatin can also be used to reduce such risk even if your cholesterol levels are normal. You should maintain a standard cholesterol-lowering diet during treatment.
Q. Is Atorvastatin diuretic?
Atorvastatin is not a diuretic. It is a lipid lowering agent which belongs to a group of medicines known as statins.
Q. Is Atorvastatin better than simvastatin and pravastatin?
Atorvastatin, simvastatin, and pravastatin belong to the same category of medications with similar action and similar side effects, but their effect may vary upon individual response. Always consult your doctor regarding its use.
Q. Can the use of Atorvastatin cause diabetes?
Diabetes has not been reported as a side effect of Atorvastatin. However, it may increase your blood sugar levels. So, it is very important that you monitor your blood sugar levels regularly if you are taking Atorvastatin. Also, share with your doctor if you have diabetes mellitus and you are advised to take Atorvastatin as your doctor will monitor you while you are taking this medicine.
Q. Can Atorvastatin lower the level of triglycerides?
Atorvastatin belongs to a group of medicines known as statins, which are lipid (fat) lowering medicines. Atorvastatin is used to lower lipids known as cholesterol and triglycerides in the blood when a low-fat diet and lifestyle changes on their own have failed.
Q. Does Atorvastatin cause weight loss?
Atorvastatin has not been reported to cause weight loss. However, weight gain has been reported as an uncommon side effect. Please consult your doctor if you experience weight loss while you are taking Atorvastatin.
Q. Does Atorvastatin cause erectile dysfunction?
Atorvastatin can cause erectile dysfunction although this side effect is not very clear. Please consult your doctor if you experience erectile dysfunction while you are taking Atorvastatin.
Q. Does Atorvastatin cause diarrhea?
Diarrhea is a common side effect of Atorvastatin. Please consult your doctor if you experience diarrhea after taking Atorvastatin as the dose of your medicine may need to be changed.
Q. Does Atorvastatin cause memory loss?
Loss of memory is an uncommon side effect of Atorvastatin, which may affect up to 1 in 100 people. Please consult your doctor if you experience any symptoms of memory loss after taking Atorvastatin.
Q. Does Atorvastatin cause frequent urination?
Atorvastatin has not been reported to cause frequent urination. Please consult your doctor if you experience increased urinary frequency after taking Atorvastatin.
Q. Does Atorvastatin cause high blood pressure?
Atorvastatin has not been reported to cause high blood pressure. Please consult your doctor if you experience any symptoms of high blood pressure while taking Atorvastatin.
Q. Is Atorvastatin a blood thinner?
Atorvastatin is not a blood thinner. Atorvastatin is a lipid lowering agent which belongs to a group of medicines known as statins.
Q. Is Atorvastatin safe to take?
Atorvastatin is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. Is Atorvastatin a beta blocker?
Atorvastatin is not a beta blocker. Atorvastatin is a lipid lowering agent which belongs to a group of medicines known as statins.
Q. Is Atorvastatin a controlled substance?
Atorvastatin is not a controlled substance under the Controlled Substance Act (CSA). Controlled substances are drugs that are strictly regulated to reduce the risk of abuse and illegal distribution. To determine the level of restriction placed on a particular controlled substance, five different categories (or "Schedules") are used. A controlled substance will belong to Schedule I, II, III, IV, or V, with Schedule V being the least restricted.
Q. Is Atorvastatin an Angiotensin Converting Enzyme (ACE) inhibitor?
Atorvastatin is not an Angiotensin Converting Enzyme (ACE) inhibitor. Atorvastatin is a lipid lowering agent which belongs to a group of medicines known as statins.
Q. Can I take Atorvastatin with metformin?
Atorvastatin can be taken with metformin. No drug-drug interactions have been reported between the two. However, interactions can occur. Please consult your doctor before taking the two medicines together.
Q. Can I take Atorvastatin with ibuprofen?
Atorvastatin can be taken with ibuprofen. No drug-drug interactions have been reported between the two. However, interactions can occur. Please consult your doctor before taking the two medicines together.
Q. Can I take Atorvastatin with milk?
No information is available for the use of Atorvastatin with milk. However, it can be taken any time of the day, with or without food. Please consult your doctor.
Q. Can I take Atorvastatin with fenofibrate?
Both fenofibrate and Atorvastatin have similar effects and they may increase the effects of each other. Fenofibrate may also increase side effects like risk for rhabdomyolysis (condition in which damaged skeletal muscle breaks down rapidly). Monitoring is required when these two drugs are taken together. Please consult your doctor before taking these two medicines together.
Q. Can I take Atorvastatin with levothyroxine?
Atorvastatin can be taken with levothyroxine. No drug-drug interactions have been reported between the two. However, interactions can occur. Please consult your doctor before taking the two medicines together.
Q. Can I take Atorvastatin with amlodipine?
Atorvastatin can be taken with amlodipine. No drug-drug interactions have been reported between the two. However, interactions can occur. Please consult your doctor before taking the two medicines together.
Q. Can I take Atorvastatin with erythromycin?
Erythromycin can increase the level or effect of Atorvastatin by decreasing its breakdown which may lead to increased side effects like muscle weakness (myopathy). So, close monitoring is required when these two drugs are taken together. Please consult your doctor before taking the two medicines together.
Q. Can I take Atorvastatin with metronidazole?
Metronidazole can increase the level or effect of Atorvastatin by decreasing its breakdown which may lead to increased side effects like muscle weakness (myopathy) with Atorvastatin. So, close monitoring is required when these two drugs are taken together. Please consult your doctor before taking the two medicines together.
Q. Can I take Atorvastatin with clarithromycin?
Clarithromycin can increase the level or effect of Atorvastatin by decreasing its breakdown which may lead to increased side effects like muscle weakness (myopathy) with Atorvastatin. So, close monitoring is required when these two drugs are taken together. Please consult your doctor before taking the two medicines together.
Q. Does Atorvastatin cause gas?
Flatulence (gas or wind) is one of the common side effects associated with the use of Atorvastatin. If you have any such symptom while taking the drug, consult your doctor.
Q. Does Atorvastatin lower blood pressure?
Atorvastatin is a lipid-lowering drug used in the treatment of increased cholesterol levels and for the prevention of cardiovascular diseases. However, a meta-analysis of different clinical trial shows that Atorvastatin has a small blood pressure lowering effect.
Q. Does Atorvastatin affect the liver?
Atorvastatin is associated rarely with hepatobiliary disorders. Its use is also linked with abnormal liver function test and hence a periodic test of the liver functions is recommended.
Q. Does Atorvastatin cause itching?
Atorvastatin use has been associated with urticaria (itching) and skin rash. If you experience any such symptom while using the drug, consult your doctor.
Q. Does Atorvastatin thin blood?
Atorvastatin is not a blood-thinner. It is a lipid-lowering agent and acts by inhibiting HMG-CoA reductase enzyme.
Q. What is Atorvastatin?
Atorvastatin is a lipid-lowering drug which belongs to group of medications called statins (lipid-lowering agents) or HMG CoA reductase inhibitors. It acts by blocking the enzyme HMG CoA reductase and formation of cholesterol, thus, lowering the blood lipid levels.
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