Neupokine 300mcg Solution for Injection is used to prevent infections after chemotherapy. It is a growth factor that stimulates the bone marrow to produce white blood cells. These cells protect the body against infections.
Neupokine 300mcg Solution for Injection is given as an injection by a qualified medical professional. You should continue to take as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. You might be asked to get regular tests done to check the number of blood cells in your blood and your bone density level while you are taking this medicine.
The most common side effects of this medicine include bone pain, weakness, joint pain, headache, and rash. Other than this, pain or redness at the site of injection is common. But, inform your doctor if you notice a lump, swelling, or bruising that does not go away. It might not prevent you from all kinds of infection, hence inform your doctor if you notice fever, chills, rash, sore throat, and swelling around the face or neck.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Neupokine Solution for Injection
Prevention of Infections after chemotherapy
Benefits of Neupokine Solution for Injection
In Prevention of Infections after chemotherapy
Neupokine 300mcg Solution for Injection increases the production of white blood cells by stimulating the immune system in our body. White blood cells are those cells that help us to fight infections. This medicine is really effective and must be used under medical supervision. Avoid being in crowds and wash your hands often to prevent any infections. Have plenty of fluids, unless otherwise advised by the doctor not to.
Side effects of Neupokine Solution for Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Neupokine
Pain in extremities
Increased white blood cell count
Muscle pain
Increased lactate dehydrogenase level in blood
Low blood platelets
Injection site pain
Increased uric acid level in blood
Oropharyngeal pain
Hair loss
Fatigue
Increased liver enzymes
Diarrhea
Decreased appetite
Constipation
Injection site reactions (pain, swelling, redness)
Bone pain
Weakness
Joint pain
Rash
Headache
Nausea
Back pain
How to use Neupokine Solution for Injection
Your doctor or nurse will guide you how to use this medicine.
How Neupokine Solution for Injection works
Neupokine 300mcg Solution for Injection is a growth factor that stimulates the bone marrow to produce white blood cells. These cells protect the body against infections.
.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Neupokine 300mcg Solution for Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Neupokine 300mcg Solution for Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Neupokine 300mcg Solution for Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Neupokine 300mcg Solution for Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Neupokine 300mcg Solution for Injection in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Neupokine 300mcg Solution for Injection in patients with liver disease. Please consult your doctor.
What if you forget to take Neupokine Solution for Injection?
If you miss a dose of Neupokine 300mcg Solution for Injection, please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
Neupokine 300mcg Solution for Injection reduces the risk of infection in people treated with chemotherapy.
It is usually given as a daily injection into the tissue just under the skin or into the vein.
You will normally receive your first dose at least 24 hours after your chemotherapy or bone marrow transplant.
Store it in the refrigerator, protect it from light, and don't shake it.
For a more comfortable injection, leave the syringe at room temperature for 30 minutes before using it.
Pain or redness in the area of injection is common. Let your doctor know if you notice a lump, swelling, or bruising that doesn't go away.
Use caution while driving or doing anything that requires concentration as Neupokine 300mcg Solution for Injection may cause dizziness.
Your doctor may get regular tests done to monitor the number of blood cells in your blood, and your bone density level while you are receiving treatment with this medicine.
Stop taking Neupokine 300mcg Solution for Injection and inform your doctor if you have a fever, shortness of breath, fast rate of breathing or trouble breathing.
Neupokine 300mcg Solution for Injection reduces the risk of infection in people treated with chemotherapy.
It is usually given as a daily injection into the tissue just under the skin or into the vein.
You will normally receive your first dose at least 24 hours after your chemotherapy or bone marrow transplant.
Store it in the refrigerator, protect it from light, and don't shake it.
For a more comfortable injection, leave the syringe at room temperature for 30 minutes before using it.
Pain or redness in the area of injection is common. Let your doctor know if you notice a lump, swelling, or bruising that doesn't go away.
Use caution while driving or doing anything that requires concentration as Neupokine 300mcg Solution for Injection may cause dizziness.
Your doctor may get regular tests done to monitor the number of blood cells in your blood, and your bone density level while you are receiving treatment with this medicine.
Stop taking Neupokine 300mcg Solution for Injection and inform your doctor if you have a fever, shortness of breath, fast rate of breathing or trouble breathing.
Fact Box
Chemical Class
Cytokine Glycoprotein
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Granulocyte-Colony Stimulating Factor (G-CSF)
Patient concerns
Plz check the report and reply She is my wife report one of hospital where operated the tumot operation and one of from delhi srl and last one from tmh mumbai After the diagnosis docror advice rediation now 1 st rediation therapy is finished and doctor giving now nublast 250mg tab So plz check the report and tell me as per the tata memorial final report what is the condition for patient She can live normal life or she can dead in ahead Doctor tells with my family she can live with treatment more than 1 to 2 years Is it right or wrong
Dr. Vijay Sharnangat
Medical Oncology and Hematology
You are on right treatmentAfter completion of radiation therapy you need to take chemotherapyThat tablet is the chemotherapy
My mother have lung cancer adenocarcinoma spread in bone also. After six chemotherapy lung cancer burn out diseases.but in bone not result. First eighth chemotherapy zometa . Last two chemotherapy give them xgeva120 . Can bone cancer cure?
What would be the best treatment for this disease. As i am very confused about doctor's advice. Some said to start chemo 6 cycles without even pet scan. Doctor from hcg Bangalore advised for radiation for 28 set. But doctor's from Bangalore Baptist hospital advised for 3 cycle of chemo therapy finally i did the pet scan and tomorrow have a appointment with the doctor from Baptist hospital.
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Ideal treatment for these tumor would be chemotherapy along with radiation therapy, but your patient has fistula after surgery so radiation would not be possible, so ahead with chemotherapy. You can have 4 to 6 cycles.
What is Neupokine 300mcg Solution for Injection used for?
Neupokine 300mcg Solution for Injection is a medicine that helps the body make more white blood cells. It is usually given to people receiving chemotherapy or bone marrow transplants to reduce the risk of infections.
Who should not use Neupokine 300mcg Solution for Injection?
Neupokine 300mcg Solution for Injection should not be used by anyone allergic to filgrastim, pegfilgrastim, lenograstim, lipegfilgrastim, or any of the other ingredients present in this medicine. It should also be avoided in people with rare conditions like Kostmann’s syndrome (a rare genetic disorder characterized by a severe deficiency of neutrophils, a type of white blood cell crucial for fighting bacterial infections) if they have developed certain serious blood problems.
What precautions should I take before starting Neupokine 300mcg Solution for Injection?
Before starting Neupokine 300mcg Solution for Injection, inform your doctor if you have sickle cell disease, osteoporosis, lung problems, or if you have planned bone marrow or stem cell testing. Your doctor will also monitor your blood counts regularly during treatment.
Can Neupokine 300mcg Solution for Injection affect the spleen?
In rare cases, Neupokine 300mcg Solution for Injection can cause the spleen to become enlarged, which may lead to a rupture. Signs include pain in the upper left side of your stomach or shoulder. You should seek medical help immediately if this happens.
Can Neupokine 300mcg Solution for Injection cause lung problems?
Yes. Neupokine 300mcg Solution for Injection has been linked to lung-related side effects such as cough, fever, difficulty breathing, or fluid in the lungs. If you notice these symptoms, contact your doctor right away.
What are the serious side effects of Neupokine 300mcg Solution for Injection that I should watch for?
Serious side effects of Neupokine 300mcg Solution for Injection may include severe allergic reactions, chest pain, sudden trouble breathing, swelling, high white blood cell counts, or signs of inflammation in the blood vessels. These require urgent medical attention.
Can Neupokine 300mcg Solution for Injection increase the risk of cancer or tumour growth?
In some very rare cases, Neupokine 300mcg Solution for Injection has been linked to changes in bone marrow and blood cells. It is usually used under strict monitoring in people with cancer or blood disorders, so your doctor will check your blood counts often.
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
Masters SB. Agents Used in Anemias; Hematopoetic Growth Factors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 581-82.
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
Cancer Research Uk. Granulocyte Colony Stimulating Factor. [Accessed 27 Mar. 2019] (online) Available from: