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Mefliam Plus Tablet is a combination medicine that is prescribed to treat malaria. It fights against the infection by preventing the growth of the parasites inside the body.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 25 May 2026 | 05:59 PM (IST)
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General Information

The content is shown in English
Mefliam Plus Tablet image
Mefliam Plus Tablet image

Product introduction

Mefliam Plus Tablet is a prescription medicine. It is to be taken with food and take it at a fixed time regularly. Take the medicine in the dose and duration advised by your doctor. Do not consume more than the recommended dose, as this may have harmful effects on your body. A missed dose should be taken as soon as you remember. The course of the treatment should be completed for better efficacy.

Some common side effects of this medicine are headaches, loss of appetite, weakness, pain in muscles, and joint pain. You may also feel dizzy, thus it is advised not to drive or operate machinery. To overcome dizziness you should drink plenty of fluid. If any of the side effects get aggravated, contact your doctor immediately.

Before taking this medicine, you should tell your doctor if you are taking any medication for any health conditions. Pregnant or breastfeeding women should also consult with their doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine.

Uses of Mefliam Plus Tablet

Benefits of Mefliam Plus Tablet

Treatment of Malaria
Malaria is a serious or life-threatening illness that is spread by a parasite that enters the human body by the bite of infected mosquitoes. Mefliam Plus Tablet is an antimalarial medicine and is used to treat malaria. It kills the infection-causing parasite and stops the further spread of the infection in the body. Do not use this medicine for treating any other condition without consulting your doctor.

Side effects of Mefliam Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Mefliam Plus
  • Muscle pain
  • Nausea
  • Vomiting
  • Upset stomach
  • Stomach pain
  • Dizziness
  • Headache
  • Sleepiness
  • Insomnia (difficulty in sleeping)
  • Skin rash
  • Tiredness

How to use Mefliam Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mefliam Plus Tablet should be taken with or after food.

How Mefliam Plus Tablet works

Mefliam Plus Tablet is a combination of two antiparasitic medicines: Artesunate and Mefloquine, which treats malaria. These medicines work by increasing the levels of haeme in the blood, a substance toxic to the malarial parasite. This kills the parasite and stops the infection from spreading.

Quick tips

  • You have been prescribed Mefliam Plus Tablet for the treatment of acute uncomplicated malaria that is resistant to other antimalarial medications such as chloroquine.
  • Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
  • It should be taken with food or drinks rich in fat such as milk.
  • It may cause fatigue and dizziness. Use caution while driving or doing anything that requires concentration.
  • If you vomit within 1 hour of taking the tablets, take another dose. 
  • Inform your doctor if you have kidney, liver or heart disease.
  • Tips to reduce the chance of being bitten by mosquitoes:
    • Wear light-coloured and covered clothing when you are outside after sunset.
    • Use insect repellent creams or sprays on parts of your body not covered by clothing.
    • Spray to kill any mosquitoes that may have entered rooms in spite of screening.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Mefliam Plus Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Mefliam Plus Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Mefliam Plus Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Mefliam Plus Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Mefliam Plus Tablet can cause dizziness, loss of balance and mental problems and this may affect your ability to drive.
Kidney

Kidney

CAUTION
Mefliam Plus Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Mefliam Plus Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Mefliam Plus Tablet is not recommended in patients with severe liver disease.

Fact Box

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Therapeutic Class

ANTI MALARIALS
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Vendor Details

Country of origin: India
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