Author Details
Written By
MS, BDS
Reviewed By
MD, MBBS
Last updated
25 Nov 2025 | 03:07 PM (IST)

We provide you with authentic, trustworthy and relevant information

Want to know more

Have issue with the content?

Report Problem

Leother Forte 20 mg/120 mg Tablet XL

rx_imgPrescription Required
Storage
Store below 30°C

Product introduction

Leother Forte 20 mg/120 mg Tablet XL is a combination medicine that is prescribed to treat malaria. It fights against the infection by preventing the growth of the parasites inside the body.

Leother Forte 20 mg/120 mg Tablet XL is a prescription medicine. It is to be taken with food and take it at a fixed time regularly. Take the medicine in the dose and duration advised by your doctor. Do not consume more than the recommended dose, as this may have harmful effects on your body. A missed dose should be taken as soon as you remember. The course of the treatment should be completed for better efficacy.

Some common side effects of this medicine are headaches, loss of appetite, weakness, pain in muscles, and joint pain. You may also feel dizzy, thus it is advised not to drive or operate machinery. To overcome dizziness you should drink plenty of fluid. If any of the side effects get aggravated, contact your doctor immediately.

Before taking this medicine, you should tell your doctor if you are taking any medication for any health conditions. Pregnant or breastfeeding women should also consult with their doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine.


Uses of Leother Tablet XL

Benefits of Leother Tablet XL

In Treatment of Malaria

Malaria is a serious or life-threatening illness that is spread by a parasite that enters the human body by the bite of infected mosquitoes. Leother Forte 20 mg/120 mg Tablet XL is an antimalarial medicine and is used to treat malaria. It kills the infection-causing parasite and stops the further spread of the infection in the body. Do not use this medicine for treating any other condition without consulting your doctor.

Side effects of Leother Tablet XL

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Leother

  • Muscle pain
  • Joint pain
  • Headache
  • Loss of appetite
  • Dizziness
  • Weakness

How to use Leother Tablet XL

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Leother Forte 20 mg/120 mg Tablet XL should be taken with or after food.

How Leother Tablet XL works

Leother Forte 20 mg/120 mg Tablet XL is a combination of two antiparasitic medicines: Arteether and Lumefantrine, which treats malaria. These medicines work by increasing the levels of haeme in the blood, a substance toxic to the malarial parasite. This kills the parasite and stops the infection from spreading.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Leother Forte 20 mg/120 mg Tablet XL. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
The safety of Leother Forte 20 mg/120 mg Tablet XL during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Leother Forte 20 mg/120 mg Tablet XL during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Leother Forte 20 mg/120 mg Tablet XL may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Leother Forte 20 mg/120 mg Tablet XL should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
No dose adjustment is recommended in patients with severe kidney disease.
Liver
CAUTION
Leother Forte 20 mg/120 mg Tablet XL should be used with caution in patients with severe liver disease. Dose adjustment may be needed.
No dose adjustment is recommended in patients with severe liver disease.

What if you forget to take Leother Tablet XL?

If you miss a dose of Leother Forte 20 mg/120 mg Tablet XL, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Take Leother Forte 20 mg/120 mg Tablet XL with a high-fat meal (like milk or curd-based food) to improve absorption and enhance effectiveness.
  • Complete the full course exactly as prescribed, even if symptoms improve early, to fully clear the malaria infection.
  • Avoid taking Leother Forte 20 mg/120 mg Tablet XL with grapefruit or grapefruit juice, as it may interfere with how the medicine works in your body.
  • If you feel dizzy or weak, rest and stay hydrated, as these can be common early effects while your body fights malaria.
  • If you vomit within 1 hour of taking the tablets, take another dose. 
  • Let your doctor know if you have any history of heart rhythm problems, as this medicine may affect heart activity

Fact Box

Habit Forming
No
Therapeutic Class
ANTI MALARIALS

Patient concerns

Suffering from maleria since 10 days please give me prescription
Dr. Pushkar Mani
Physician
how do u know u have malariaand which type malaria u have
Which medicine use for Malaria? What is eating in Malaria?
Dr. Saurav Arora
Homeopathy
The medicine depends upon symptoms and stage of disease

FAQs

What is Leother Forte 20 mg/120 mg Tablet XL used for?

Leother Forte 20 mg/120 mg Tablet XL is used to treat uncomplicated malaria caused by Plasmodium falciparum. This medicine helps quickly reduce the number of malaria parasites in the blood.

Should I take Leother Forte 20 mg/120 mg Tablet XL with food?

Yes, you should take Leother Forte 20 mg/120 mg Tablet XL with food. Leother Forte 20 mg/120 mg Tablet XL works better when taken with food or a milky drink, as it improves the absorption of the medicine.

Who should not take Leother Forte 20 mg/120 mg Tablet XL?

Individuals should not take Leother Forte 20 mg/120 mg Tablet XL if they are allergic to artemether, lumefantrine, or any ingredients present in Leother Forte 20 mg/120 mg Tablet XL. It should also be avoided in people with heart rhythm problems or those taking other medicines that affect heart rhythm (QT-prolonging drugs). Use is not recommended in cases of severe kidney or liver disease. Leother Forte 20 mg/120 mg Tablet XL should not be used during the first trimester of pregnancy. It is also contraindicated with strong medications that affect CYP3A4, such as rifampin, phenytoin, or St. John’s wort.

Can Leother Forte 20 mg/120 mg Tablet XL affect my heart?

Yes, Leother Forte 20 mg/120 mg Tablet XL can affect heart rhythm by prolonging the QT interval. If you have heart conditions or take other QT-prolonging medicines, talk to your doctor before using this medication.

What are the serious side effects of Leother Forte 20 mg/120 mg Tablet XL?

The serious side effects of Leother Forte 20 mg/120 mg Tablet XL may include irregular heartbeat, allergic reactions (rash, swelling, difficulty breathing), liver problems, and/or seizures or confusion (rare). Reach out to your doctor right away if you notice any of these symptoms.

What should I do if I vomit after taking Leother Forte 20 mg/120 mg Tablet XL?

If you vomit within 1 to 2 hours of taking Leother Forte 20 mg/120 mg Tablet XL, you should repeat the dose. If you vomit again, your doctor might need to switch to another antimalarial treatment.

What warning signs should I watch for during Leother Forte 20 mg/120 mg Tablet XL treatment?

During Leother Forte 20 mg/120 mg Tablet XL treatment, seek immediate medical attention if you experience severe dizziness or fainting, irregular heartbeat, severe nausea/vomiting, dark urine, yellowing of skin/eyes, unusual bleeding or bruising, and severe headache with confusion.

How do I know if Leother Forte 20 mg/120 mg Tablet XL is working?

You can tell Leother Forte 20 mg/120 mg Tablet XL is effective if you notice improvements such as reduced fever within 24 to 48 hours, symptoms (chills, body aches) lessen, appetite improves, energy levels increase, etc. Even if you feel better, complete the full course of treatment as prescribed to ensure the infection is fully treated.

What precautions should I take during Leother Forte 20 mg/120 mg Tablet XL treatment?

Important precautions during Leother Forte 20 mg/120 mg Tablet XL treatment include avoiding driving if you feel dizzy, staying hydrated, completing the full course, reporting unusual symptoms, avoiding strenuous activity, and getting adequate rest.

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Lumefantrine. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2009 [revised Mar. 2015]. [Accessed 30 Mar. 2019] (online) Available from:External Link

Marketer details

Name: Leo Pharmaceuticals
Address: LEO Pharma A/S, Industriparken 55, DK-2750 Ballerup, Danmark
Country of origin: India

NOT FOR SALE
We do not facilitate sale of this product at present

INDIA’S LARGEST HEALTHCARE PLATFORM

  • 260m+
    Visitors
  • 31m+
    Orders Delivered
  • 1800+
    Cities
Get the link to download App
  • Reliable

    All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

  • Secure

    Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

  • Affordable

    Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

LegitScript approved
India's only LegitScript and ISO/ IEC 27001:2022 certified online healthcare platform

Access medical and health information

Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.

visamastercardamerican expressrupaynet bankingcash on delivery