Author Details
Written By
MDS, BDS
Reviewed By
MD (Pharmacology), MBBS
Last updated
10 Dec 2024 | 01:13 AM (IST)

We provide you with authentic, trustworthy and relevant information

Want to know more

Have issue with the content?

Report Problem

Lefen MR 100mg/325mg/250mg Tablet


Product introduction

Lefen MR 100mg/325mg/250mg Tablet is a combination medicine that helps in relieving muscular pain. It works by blocking the release of certain chemical messengers that cause pain, inflammation, and fever. This improves the movement of muscles and provides relief from pain and discomfort.

Lefen MR 100mg/325mg/250mg Tablet can be taken with or without food. The dose and duration will depend on the severity of your condition. You should keep taking the medicine even if you feel better until the doctor says it is alright to stop using it.

Using this medicine may cause common side effects such as nausea, vomiting, heartburn, stomach pain, diarrhea, and loss of appetite. If these persist or get worse, let your doctor know. In general, you should try to use the smallest amount necessary to control your symptoms.

Before using the medicine, you should tell your doctor if you have any other medical conditions or disorders. To make sure it is safe, you should let your doctor know all the other medicines you are taking. Also, tell your doctor if you have any problems with the liver or kidneys. You should avoid the consumption of alcohol while on treatment with this medicine. Pregnant and breastfeeding women should consult their doctors first before using the medicine.

Uses of Lefen MR Tablet

  • Treatment of Muscular pain

Benefits of Lefen MR Tablet

In Treatment of Muscular pain

Lefen MR 100mg/325mg/250mg Tablet is a combination medicine that is used to relieve pain, inflammation, and swelling in conditions that affect muscles. Also, it effectively relieves muscle stiffness or spasm, thereby improving muscle movement. It works by blocking chemical messengers in the brain that tell us we have pain.

Take it as it is prescribed to get the most benefit. Do not take more or longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Lefen MR Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Lefen MR

  • Nausea
  • Vomiting
  • Heartburn
  • Stomach pain
  • Diarrhea
  • Loss of appetite
  • Tiredness
  • Sleepiness

How to use Lefen MR Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lefen MR 100mg/325mg/250mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Lefen MR Tablet works

Lefen MR 100mg/325mg/250mg Tablet is a combination of two pain relieving medicines (Aceclofenac and Paracetamol) and a muscle relaxant (Chlorzoxazone). The pain relieving medicines work by blocking the release of certain chemical messengers in the brain that cause pain and inflammation (redness and swelling). The muscle relaxant works on the centers in the brain and spinal cord to relieve muscle stiffness or spasm, thereby improving muscle movement.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Lefen MR 100mg/325mg/250mg Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Lefen MR 100mg/325mg/250mg Tablet during pregnancy is not available. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Lefen MR 100mg/325mg/250mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Lefen MR 100mg/325mg/250mg Tablet may cause side effects which could affect your ability to drive.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Lefen MR 100mg/325mg/250mg Tablet in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Lefen MR 100mg/325mg/250mg Tablet in patients with liver disease. Please consult your doctor.

What if you forget to take Lefen MR Tablet?

If you miss a dose of Lefen MR 100mg/325mg/250mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Lefen MR 100mg/325mg/250mg Tablet
₹6.74/Tablet
₹5.01/tablet
26% cheaper
Glenfenac MR 100mg/325mg/250mg Tablet
Glenmark Pharmaceuticals Ltd
₹5.51/tablet
18% cheaper
Dolokind-MR Tablet
Mankind Pharma Ltd
₹8.05/tablet
19% costlier
Dolowin-MR Tablet
Micro Labs Ltd
₹10/tablet
48% costlier
₹8.95/tablet
33% costlier

Quick tips

  • Avoid consuming alcohol when taking Lefen MR 100mg/325mg/250mg Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
  • Older adults may have increased drowsiness, confusion, and higher risk of falling as a result of taking Lefen MR 100mg/325mg/250mg Tablet.
  • Do not take it with any other medicine containing acetaminophen (drugs for pain/fever or cough-and-cold) without asking your doctor first. 

Fact Box

Habit Forming
No
Therapeutic Class
PAIN ANALGESICS

Patient concerns

arrow
I have a fever since last 3 days. Widal test is positive. Maleria Negetive. Local doctor gives pulmocef cv 500. Ocid qrs 20. Lefen mr. Deriphilline retard 300. When i take medicine fever down in half hour. After 5-6 hour fever again. Also i have serious cough and noesia. I am taking potclor syrup for cough after consultation. But no result.
Dr. Pushkar Mani
Physician
deriphiline is not requiredtake Taxim o 200 mg twice daily for 8 daysornidazole 200 mg twice daily for 8 daysparacetamol 500 mg twice daily for 7 dayspantop D once daily in empty stomach for 10 dayscapsule zevit forte twice daily for 10 days
I feel some pain around the heart and I have already consulted with cardiology doctor he advised to TMT , ECO, ECG AND MANY OTHER Blood test after all this report doctor said everything is normal but pain remain the same and in the evening I feel dry my throat and around chest please advise
Dr. Tapas Kumbhkar
Internal Medicine
If your all reports are normal Then this chest pain may be muscular pain
arrow

FAQs

What is Lefen MR 100mg/325mg/250mg Tablet?

Lefen MR 100mg/325mg/250mg Tablet is a combination of three medicines: Aceclofenac, Paracetamol and Chlorzoxazone. This medicine helps in relieving muscle pain by relaxing the affected muscles. It relieves pain caused due to muscle spasm, cramp or injury. It also lowers certain chemical substances in the body that cause pain.

What can I do along with Lefen MR 100mg/325mg/250mg Tablet to reduce muscle pain?

If you are suffering from muscle pain due to muscle injury or overuse, you should take rest. Taking rest will help you avoid any further injury and help you recover efficiently. Make sure that you take plenty of sleep and try to reduce stress. Applying ice pack to the affected area may help in relieving pain and inflammation. If your muscle pain is due to some other disease, follow the advice of your doctor.

Can I get addicted to Lefen MR 100mg/325mg/250mg Tablet?

No, there are no reports of any patient getting addicted to Lefen MR 100mg/325mg/250mg Tablet.

Can I stop taking Lefen MR 100mg/325mg/250mg Tablet when my pain is relieved?

Lefen MR 100mg/325mg/250mg Tablet is usually used for short term and can be discontinued when your pain is relieved. However, Lefen MR 100mg/325mg/250mg Tablet should be continued if you are advised by your doctor to do so.

Can the use of Lefen MR 100mg/325mg/250mg Tablet cause dizziness?

Yes, the use of Lefen MR 100mg/325mg/250mg Tablet can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for some time and resume once you feel better.

Can the use of Lefen MR 100mg/325mg/250mg Tablet cause damage to liver?

Lefen MR 100mg/325mg/250mg Tablet contains Paracetamol and Chlorzoxazone, both these medicines are known to cause harm to the liver especially when taken in doses above the recommended level. Also, avoid drinking alcohol while taking this medicine, as it may further increase your risk of liver damage. Use of this medicine should preferably be avoided in patients with underlying liver disease. Contact your doctor immediately if you notice any early signs and symptoms of liver damage. These symptoms may include fever, rash, loss of appetite, nausea, vomiting, fatigue, stomach pain, dark urine, yellow skin or eyes and abnormal live enzymes.

How long will Lefen MR 100mg/325mg/250mg Tablet take to act?

It may take about an hour to notice the initial benefits of pain relief after taking Lefen MR 100mg/325mg/250mg Tablet.

What if I forget to take Lefen MR 100mg/325mg/250mg Tablet?

If you forget to take the scheduled dose of Lefen MR 100mg/325mg/250mg Tablet and it is almost time for your next dose, skip the dose you missed and take your next dose at the scheduled time. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose you missed because this may increase the risk of unwanted side effect due to overdosage. If you are not sure what to do, consult your doctor about how to manage a situation like this.

Will Lefen MR 100mg/325mg/250mg Tablet be more effective if taken in higher than recommended doses?

No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms that are not relieved by the recommended doses, please consult your doctor for re-evaluation.

Are there any specific contraindications associated with the use of Lefen MR 100mg/325mg/250mg Tablet?

The use of Lefen MR 100mg/325mg/250mg Tablet is considered to be harmful in patients with known allergy to any of the components or excipients of this medicine. The use of this medicine should preferably be avoided in patients with a history of stomach ulcers or active, recurrent stomach ulcer / bleeding. It should also be avoided in patients with a history of heart failure, high blood pressure, and liver or kidney disease.

Does Lefen MR 100mg/325mg/250mg Tablet expire?

Yes, Lefen MR 100mg/325mg/250mg Tablet does expire. Please check the expiry date written on the pack of this medicine. Do not use Lefen MR 100mg/325mg/250mg Tablet after the expiry date.
Related lab tests

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Drugs.com. Chlorzoxazone. [Accessed 02 Apr. 2019] (online) Available from:External Link
  2. DailyMed. Aceclofenac. [Accessed 23 Apr. 2019] (online) Available from:External Link
  3. ScienceDirect. Chlorzoxazone. [Accessed 02 Apr. 2019] (online) Available from:External Link
  4. ScienceDirect. Paracetamol. [Accessed 02 Apr. 2019] (online) Available from:External Link

Marketer details

Name: Lebon Pharmaceuticals
Address: 603, G-1, Flourite, Moraj Residency, Palm Beach Road, Vashi, Mumbai. 4007005
Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.

67.4
Inclusive of all taxes
MRP68  1% OFF
10.0 tablets in 1 strip
SOLD OUT
Notify me
Available options
Available options
Same salt composition:Aceclofenac (100mg), Paracetamol (325mg), Chlorzoxazone (250mg)
https://onemg.gumlet.io/epf1dtoymcv3sbkzuspl.png
Same salt composition
https://onemg.gumlet.io/qkdhgo7ram1mle08cya9.png
Verified by doctors
https://onemg.gumlet.io/ehvn8wef9oaoewteak8d.png
Popularly bought
https://onemg.gumlet.io/xnv1s7snefeql2hkalfr.png
Trusted quality
Why buy these from 1mg?question-mark

INDIA’S LARGEST HEALTHCARE PLATFORM

260m+
Visitors
31m+
Orders Delivered
1800+
Cities
Get the link to download App
Reliable

All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

LegitScript approved
India's only LegitScript and ISO/ IEC 27001:2022 certified online healthcare platform

Know more about Tata 1mgdownArrow

Access medical and health information

Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.