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MRP: Rs. 142.43 for 1 tube(s) (15 GM cream each)
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Composition for KETRIPLIN

Amitriptyline(40 mg),Ketamine(20 mg)

food interaction for KETRIPLIN

alcohol interaction for KETRIPLIN

pregnancy interaction for KETRIPLIN

lactation interaction for KETRIPLIN

Avoid Ketriplin cream with grapefruit juice.
Ketriplin cream may cause excessive drowsiness and calmness with alcohol.
Ketriplin cream may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Amitriptyline(40 mg)


Amitriptyline is used in the treatment of depression and night time bed wetting (enuresis) in children.

How it works

Amitriptyline belongs to class of medication called as tricyclic antidepressant. It acts by changing levels of certain chemicals in the brain (norepinephrine, serotonin) that helps in improving the mood and mental balance.

Common side effects

Vomiting, Nausea, Tingling sensation of extremity, Numbness of extremity, Increase sensitivity (hyperesthesia), Drowsiness, Altered libido, Blurred vision, Change in appetite, Change in body weight, Confusion, Constipation, Dry mouth, Difficulty in urination, Fatigue, Headache, Increased sweating, Unsteadiness, Nightmare
Ketamine(20 mg)


Ketamine is used as an anesthetic agent during surgical procedures.

How it works

Ketamine belongs to class of medications known as general anesthetics. It acts on the nervous system and induces sedation or sleep, immobility and marked analgesia.

Common side effects

Vomiting, Nausea, Shortness of breath, Hallucination, Increased saliva production, Injection site pain, Loss of appetite, Muscle twitching, Nightmare


No substitutes found

Expert advice for KETRIPLIN

  • Do not consume grapefruit juice.
  • Do not suddenly stop taking your medicine.
  • Amitriptyline can make you dizzy or sleepy. So avoid driving or performing activities that require mental alertness. 
  • Avoid alcohol intake.
  • Do not take this drug if you are consuming antidepressants (monoamine oxidase inhibitors) or have been taking them within the previous two weeks.

Frequently asked questions for KETRIPLIN


Q. Is amitriptyline/Tryptomer safe?
Amitriptyline is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. What is amitriptyline/Amitone 10/Amitone plus/ Tryptomer/Tryptomer plus used for?
Amitriptyline/amitone 10/amitone plus/ tryptomer/tryptomer plus is used in the treatment of depression and nocturnal bed wetting (enuresis) in children.
Q. Is amitriptyline a benzodiazepine/MAOI/opioid/antibiotic/steroid?
No, Amitriptyline belongs to class of medication called as tricyclic antidepressant.
Q. Is amitriptyline like Xenan (diazepam)?
No, Xenan belongs to class of medication called as benzodiazepine.
Q. Is amitriptyline addictive?
No, Patients should follow the advice of the doctor regarding its use.
Q. Can I take amitriptyline/tryptomer for pain/insomnia/backache/migraine/headache/anxiety?
No, it is used to treatment of depression and nocturnal bed wetting (enuresis).
Q. Can I take amitriptyline with Prozac/zopiclone/Xanan/naproxen/prednisolone/Benadryl/
Amitriptyline can interact with Prozac/Zopiclone/Xanan/diazepam/trazadone/flexeril. Please follow doctor’s advice regarding its use.
Q. Does amitriptyline cause hair loss/ insomnia/constipation/weight gain: loss/fever/affect memory/vomiting/increased hunger/sleepiness?
Amitriptyline causes insomnia/constipation/weight gain/vomiting/increases huger. Always consult your doctor regarding possible side effects.


Q. Is ketamine addictive?
Ketamine addiction can occur if the drug is taken multiple times and may develop either a mental or physical dependence on the drug effects.
Q. Is ketamine an opiate/ narcotic/ stimulant/ controlled substance/ barbiturate?
No. Ketamine is a general anaesthetic and a controlled substance. It is not an opiate, barbiturate narcotic or stimulant.
Q. Is ketamine safe?
Ketamine is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. Is ketamine dangerous?
Ketamine is dangerous if taken at high doses. 
Q. Does ketamine make you lose weight?
Yes. Ketamine can cause loss of appetite and weight loss.


Content on this page was last updated on 29 March, 2014, by Dr. Varun Gupta (MD Pharmacology)