


Ketriplin Cream
Amitriptyline (40mg)+ Ketamine (20mg)
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Ketriplin Cream is a combination of two medicines used to treat neuropathic pain. It works by protecting the nerve fibres against damage, repairing the damaged nerves. This way it effectively relieves the pain sensation.
Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 02 Apr 2026 | 05:32 PM (IST)
Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 02 Apr 2026 | 05:32 PM (IST)
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General Information
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Product introduction
Ketriplin Cream is for external use only. You should use this in the dose and duration advised by your doctor. Clean and dry the affected area before applying this medicine to the skin. You should always wash your hands after applying it unless hands are the affected area.
There are no major side effects associated with this medicine, but it can cause some application site burning or irritation. However, these side effects are temporary and usually resolve on their own. Please consult your doctor if these do not subside or bother you.
Uses of Ketriplin Cream
Benefits of Ketriplin Cream
Neuropathic pain
Neuropathic pain is a condition that occurs when damaged or malfunctioning nerves send faulty signals to the brain, causing sensations like burning, tingling, numbness, or sharp, shooting pain. Ketriplin Cream helps reduce nerve-related pain and discomfort, allowing for better movement, improved sleep, and an overall better quality of life.
Neuropathic pain is a condition that occurs when damaged or malfunctioning nerves send faulty signals to the brain, causing sensations like burning, tingling, numbness, or sharp, shooting pain. Ketriplin Cream helps reduce nerve-related pain and discomfort, allowing for better movement, improved sleep, and an overall better quality of life.
Side effects of Ketriplin Cream
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Ketriplin
- Application site burning
- Application site irritation
- No common side effects seen
How to use Ketriplin Cream
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
How Ketriplin Cream works
Ketriplin Cream is a combination of two medicines: Amitriptyline and Ketamine. Amitriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Ketamine is a general anesthetic which works by blocking certain receptors (NMDA) thereby decreasing the sensation of pain. Together, they relieve neuropathic pain (pain from damaged nerves).
Quick tips
- Ketriplin Cream is used to treat certain types of long-lasting pain caused by damage to nerves.
- Wash your hands before and after applying Ketriplin Cream to the affected area.
- Inform your doctor if you are taking any other pain-relieving medicines.
- Along with taking Ketriplin Cream, your doctor might advise you to undergo physiotherapy to get relief from pain.
Safety advice

Alcohol
No interaction found/established

Pregnancy
CONSULT YOUR DOCTOR
The safety of Ketriplin Cream during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding
CONSULT YOUR DOCTOR
Ketriplin Cream may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving
No interaction found/established

Kidney
No interaction found/established

Liver
No interaction found/established
Fact Box
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
References
- ScienceDirect. Amitriptyline. [Accessed on 25 Apr. 2019] (online) Available from:
- ScienceDirect. Ketamine. [Accessed on 25 Apr. 2019] (online) Available from:
- PubChem. Amitriptyline. [Accessed on 25 Apr. 2019] (online) Available from:
- PubChem. Ketamine. [Accessed on 25 Apr. 2019] (online) Available from:
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User feedback
Once A Day
57%
Thrice A Day
19%
Twice A Day
19%
Four Times A Day
5%
Neuropathic pain
100%
Poor
56%
Excellent
33%
Average
11%
No Side Effect
100%
With food
50%
With or without food
50%
Average
67%
Expensive
33%
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Disclaimer
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Ajanta Pharma Limited
Address: Ajanta House, Charkop, Kandivli West, Mumbai 400 067, India
Address: Ajanta House, Charkop, Kandivli West, Mumbai 400 067, India
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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