Eprex 4000 Injection
Prescription Required
Product introduction
Eprex 4000 Injection is a medicine that helps your bone marrow to produce more red blood cells. It is used to treat a type of anemia caused by kidney disease. It is also used to treat anemia caused by cancer chemotherapy and by medicines to treat HIV.
Eprex 4000 Injection is given by injection either under the skin or into a vein, which will be decided by your doctor. Usually, the injections are given by a nurse or doctor. The dose depends on your body weight and the cause of your anemia. Iron supplements both before and during treatment may make this treatment more effective. Eprex 4000 Injection needs to be stored in a fridge but used at room temperature.
The most common side effects of taking this medicine include nausea, vomiting, fever, and increased blood pressure. It may also cause flu-like symptoms such as headache, tiredness, dizziness, and aches and pains. These side effects are most common at the start of treatment, but if they persist, your doctor may be able to suggest ways of preventing or reducing them. Tell your doctor straight away if you get any serious side effects, including seizures (fits). Sometimes, this medicine can cause serious blood clots that need urgent medical attention.
Before using Eprex 4000 Injection, you should tell your doctor if you have uncontrolled high blood pressure, heart disease, or gout (a disease of joint pain). You should also tell him/her what other medicines you are taking in case they affect this treatment. Your blood pressure should be checked often during this treatment by you or your doctor. You may also need other regular medical tests to be sure this medicine is not causing harmful effects. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.
Uses of Eprex Injection
Benefits of Eprex Injection
In Treatment of Anemia due to cancer chemotherapy
Eprex 4000 Injection helps manage anemia caused by cancer chemotherapy by stimulating the bone marrow to produce more red blood cells. This reduces the need for blood transfusions and helps improve oxygen delivery throughout the body, alleviating symptoms such as fatigue, weakness, and shortness of breath commonly experienced by chemotherapy patients. This way it improves the patient’s quality of life and supports better tolerance to ongoing cancer treatment.
In Treatment of Anemia due to chronic kidney disease
In chronic kidney disease (CKD), the kidneys produce less erythropoietin, a hormone needed for red blood cell production. Eprex 4000 Injection supplements this deficiency by stimulating the bone marrow to produce red blood cells, helping to correct anemia. This leads to increased hemoglobin levels, improved oxygen delivery, and relief from symptoms such as persistent fatigue, weakness, and breathlessness. Managing anemia helps improve patients’ energy levels, physical functioning, and overall quality of life, allowing them to perform daily activities more comfortably and with greater independence.
Side effects of Eprex Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Eprex
- Muscle spasm
- Dizziness
- Vascular occlusion
- Injection site irritation
- Stomatitis (Inflammation of the mouth)
- Weight loss
- Decreased white blood cell count (lymphocytes)
- Increased glucose level in blood
- Blood clot in the blood vessels
- High blood pressure
- Nausea
- Vomiting
- Fever
- Rash
- Joint pain
- Headache
- Insomnia (difficulty in sleeping)
- Chills
How to use Eprex Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Eprex Injection works
Eprex 4000 Injection is an erythropoiesis-stimulating agent (ESA). It works by stimulating the bone marrow (soft tissue inside the bones which produces red blood cells) to produce more red blood cells.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Eprex 4000 Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Eprex 4000 Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Eprex 4000 Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Eprex 4000 Injection may cause side effects which could affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Eprex 4000 Injection is safe to use in patients with kidney disease. No dose adjustment of Eprex 4000 Injection is recommended.
Regular monitoring of kidney function tests is advised while the patient is taking this medicine.
Regular monitoring of kidney function tests is advised while the patient is taking this medicine.
Liver
CAUTION
Eprex 4000 Injection should be used with caution in patients with liver disease. Dose adjustment of Eprex 4000 Injection may be needed. Please consult your doctor.
What if you forget to take Eprex Injection?
If you miss a dose of Eprex 4000 Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Eprex 4000 Injection
₹1764/Injection
Relipoietin 4000 IU Injection
Reliance Life Sciences
₹1161.6/injection
36% cheaper
Renocrit 4000IU Injection
Cadell Healthcare Pvt Ltd
₹1307/injection
28% cheaper
Quick tips
- Your doctor may get your blood tests done regularly to monitor the levels of hemoglobin, blood cells, and electrolytes such as potassium in your blood.
- Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure, such as severe headache, problems with your eyesight, nausea, vomiting, or fits (seizures).
- Stop taking Eprex 4000 Injection and inform your doctor if you develop shortness of breath or a skin rash.
Fact Box
Chemical Class
Amino Acids, Peptides Analogues
Habit Forming
No
Therapeutic Class
BLOOD RELATED
Action Class
Erythropoiesis-Stimulating Agents (ESAs)
Patient concerns
User feedback
Patients taking Eprex 4000 Injection
Once A Week
54%
Twice A Week
23%
Once A Month
11%
Once A Day
5%
Twice A Month
4%
Thrice A week
2%
Alternate Day
2%
What are you using Eprex Injection for?
Anemia due to*
61%
Anemia
17%
Others
11%
Anemia due to*
11%
*Anemia due to chronic kidney disease, Anemia due to cancer chemotherapy
How much was the improvement?
Excellent
52%
Poor
24%
Average
24%
What were the side-effects while using Eprex 4000 Injection?
No Side Effec*
67%
Pulmonary thr*
33%
*No Side Effect, Pulmonary thromboembolism (blood clot in the lungs)
How do you take Eprex Injection?
With food
40%
Empty stomach
40%
With or witho*
20%
*With or without food
Please rate Eprex 4000 Injection on price
Expensive
83%
Average
17%
FAQs
What to do if you use too much Eprex 4000 Injection?
Tell the doctor or nurse immediately if you think too much Eprex 4000 Injection has been injected.
When should Eprex 4000 Injection not be used?
Eprex 4000 Injection should not be used if the solution is cloudy, or if you can see particles floating in it, or if the medicine has expired. Refer to the expiry date on the label. You should also not use the medicine if you know or think that it may have been accidentally frozen or if there has been a refrigerator failure.
Can Eprex 4000 Injection be used in children?
Yes, Eprex 4000 Injection is used to treat anemia caused due to chronic kidney disease in children who are above 1 year of age. The effectiveness of Eprex 4000 Injection and side effects seen in children are similar to adults.
Can Eprex 4000 Injection affect blood pressure?
Yes, Eprex 4000 Injection can affect blood pressure. During initial therapy with Eprex 4000 Injection, blood pressure should be monitored, and those who have high blood pressure should take appropriate measures to control blood pressure. Your doctor may stop Eprex 4000 Injection if the blood pressure remains uncontrolled.
How should Eprex 4000 Injection be stored?
In the hospital, pre-filled syringes are stored unopened in a refrigerator between 2 and 8℃. If you are using this medicine at home, the pre-filled syringe must be stored in your refrigerator. Do not store it in the freezer. Allow the pre-filled syringe to reach room temperature before using it. This usually takes between 15 and 30 minutes. Eprex 4000 Injection pre-filled syringes that are being used or about to be used can be kept at room temperature (not above 25°C) for a maximum single period of 7 days. Keep these pre-filled syringes away from children and protected from light.
Want to share the information?
Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Recombinant Human Erythropoietin Alfa/Epoetin Alfa. Leiden, Netherlands: Janssen Biologics B.V; [revised Oct. 2018]. [Accessed 07 Apr. 2019] (online) Available from:
- Recombinant Human Erythropoietin Alfa/Epoetin Alfa. Amgen Inc; 1989 [revised Dec. 2013]. [Accessed 07 Apr. 2019] (online) Available from:
- Epoetin alfa [Prescribing Information]. Horsham, Pennsylvania: Janssen Products, LP; 2017. [Accessed 28 Mar. 2023] (online) Available from:
- Epoetin alfa [Prescribing Information]. Pune, Maharashtra: Emcure Pharmaceuticals Limited; 2024. [Accessed 02 Apr. 2025] (online) Available from:
- Epoetin alfa [Prescribing Information]. Vilbel, Germany: STADA Arzneimittel AG; 2012. [Accessed 02 Apr. 2025] (online) Available from:
Marketer details
Name: Janssen Pharmaceuticals
Address: Johnson & Johnson Private Limited., 501 Arena Space, Behind Majas Bus Depot, Off Jogeshwari Vikhroli Link Road, Jogeshwari (E), Mumbai 400 060
Country of origin: Switzerland
Lab tests offered by us
Related/Popular tests
₹1764
Inclusive of all taxes
MRP₹1820 3% OFF
0.4 ml in 1 prefilled syringe
SOLD OUT