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Composition for DEXAPIN


food interaction for DEXAPIN

alcohol interaction for DEXAPIN

pregnancy interaction for DEXAPIN

lactation interaction for DEXAPIN

There is no data available. Please consult doctor before consuming the drug.
Dexapin 1%/0.10% eye drop may cause excessive drowsiness and calmness with alcohol.
Dexapin 1%/0.10% eye drop may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Dexapin 1%/0.10% eye drop is probably safe to use during breastfeeding. Please consult your doctor.




Atropine is used in the form of eye drops for treatment of infections and inflammation of eyes, for relaxing the eye muscles before eye examination especially in children (cycloplegic refraction), and to widen the pupil. As a tablet and injection, it is used to reduce production of saliva and other body fluids before general anesthesia, to raise the heart rate if it has become too slow (after heart attack or certain drugs), and for relief of symptoms of organo phosphorus (pesticide) poisoning. Tablets are also used in certain inflammatory gut disorders.

How it works

Atropine belongs to class of medication called as anticholinergic drugs. It acts by blocking the activity chemicals (acetylcholine) in the body, thereby producing effects such as reduction of salivary and other body secretions, relief of abdominal pain due to cramps, increase in the heart rate, and widening of the pupil.

Common side effects

Vomiting, Nausea, Confusion, Dry mouth, Dry skin, Difficulty in urination, Eye irritation, Eyelid swelling, Altered heart rate, Eye redness, Skin redness, Tachycardia, Blurred vision, Photosensitivity, Fever


Dexamethasone is used to treat various inflammatory conditions such as allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, or breathing disorders. It is also used to treat certain types of cancer.

How it works

Dexamethasone belongs to a group of medicines called corticosteroids. It prevents late phase allergic reactions by preventing release of chemicals responsible for allergy.

Common side effects

Psychosis, Extremes of being happy or sad, Hypersensitivity reaction, Allergic reaction, Behavioual changes, Burning sensation, Delusion, Suicidal thoughts, Depression, Feeling of discomfort, Euphoria (feeling of intense excitement and happiness), Hallucination, Aggravation of schizophrenia, Increased cholesterol level in blood, Increased hair growth, Decreased potassium level in blood, Increased appetite, Increased blood pressure, Increased intraocular pressure, Increased risk of infection, Irregular menstrual cycle, Irritation, Blurred vision, Itching, Salt and water retention, Swelling, Weight gain, Fluid retention, Tendon rupture, Thinning of bones, Fracture, Stinging sensation


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Expert advice for DEXAPIN

  • Do not start or continue atropine, in any form if you are allergic to atropine or any other ingredients of the medicine.
  • Do not start or continue atropine eye drops if you wear soft contact lenses; if you have increased pressure in the eyes (glaucoma); fever or increased heart rate. 
  • Do not start or continue atropine tablets if you have a condition called pyloric stenosis characterize with difficulty for food to move from stomach into the small intestine causing pain or vomiting; or acid reflux with heartburn (gastro-oesophageal reflux) and diarrhea.
  • Avoid taking atropine if you have urinary retention, high blood pressure, any heart problem including weak heart, or high thyroid hormone level.
  • Do not take this drug if you have rare hereditary problems of intolerance to done or more types of sugar (including galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption.)
  • Do not drink alcohol while taking atropine in any form. 
  • Atropine can cause visual disturbances, giddiness and staggering and, therefore, caution has to be taken before operating an automobile or machinery or engaging in activities requiring mental alertness and coordination.

Frequently asked questions for DEXAPIN


Q. Is atropine a controlled substance?
No, it is available as prescription drug.
Q. Is atropine a beta blocker /calcium channelblocker/adrenaline/ parasympathomimetic/vasopressor?
No, atropine belongs to class of medication called as anticholinergics or cholinergic antagonist.
Q. Is atropine an agonist or antagonist?
Atropine is an antagonist of cholinergic receptors.
Q. Is atropine a narcotic drug?
No, it is not a narcotic. However, it is often available in combination with drugs that have abuse potential.
Q. Does atropine increase blood pressure/decrease heart rate/sedation/urinary retention/increase contractility?
Atropine decreases heart rate and increases blood pressure; It causes urinary retention as well as decreased contractility of gut and urinary bladder muscles. It does not cause sedation, on the contrary, it causes excitation, sleeplessness and agitation.
Q. Does atropine cross placenta?
Yes, small amount of atropine can cause placenta. Always follow your doctor’s advice regarding its use.
Q. Does atropine block activity of acetylcholine /nicotinic receptor?
Yes, atropine acts by inhibiting the activity of acetylcholine on muscarinic and nicotinic receptors.


Q. Are decadron and prednisone same as dexamethasone?
No.  Decadron is a brand name of dexamethasone. Prednisone, however, is entirely different drug. Both drugs however belong to a same class of medications called corticosteroids.
Q. Is dexamethasone a narcotic, sulfa drug, NSAID or controlled substance?
No. Dexamethasone is a corticosteroid drug which shows anti-inflammatory action. It is not a controlled substance or sulfa drug. It can be obtained only on production of valid prescription.
Q. Does dexona cause weight gain/ cause fluid retention/ heart burn/ hungry/ keep you awake/ drowsiness?
Dexona is the brand name of dexamethasone tablet, a corticosteroid. It may cause weight gain due to fluid retention properties. It should be noted that the fluid retention is a side effect of dexona and not the use. It is also known to cause heart burn and increased appetite. It does not cause drowsiness or insomnia. However, if you experience such side effects, always consult your doctor.
Q. Is dexamethasone safe?
Dexamethasone is safe if used at prescribed doses and at prescribed duration as advised by your doctor.
Q. Can I take ibuprofen, Advil, Aleve or naproxen with dexamethasone?
Advil is the brand name of ibuprofen while Aleve is the brand name of naproxen. Dexamethasone should not be used in combination with non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, diclofenac, naproxen etc., since it can cause stomach ulceration and bleeding.
Q. Can I take dexamethasone with ciprofloxacin?
Taking ciprofloxacin along with dexamethasone tablet may cause inflammation of tendon and tendon rupture especially in elderly. Hence taking this drug combination is not advisable.
Q. Can I take paracetamol, Tylenol or Benadryl with dexamethasone?
No major or clinically significant drug interaction is found with the said drugs. However, always consult your doctor before using these drugs.
Q. Can I take tums with dexamethasone?
Minor interaction between dexamethasone and tums (calcium carbonate) are reported in certain cases. Always consult your doctor before using this combination.
Q. Can I take Xanax with dexamethasone?
Minor interaction between dexamethasone and Xanax (alprazolam) are reported in certain cases. Always consult your doctor before using this combination.
Q. Is dexamethasone safe for toddlers?
It is safe if used as per indication and doses advised by the doctor.
Q. What are the uses of dexona tablet and injection?
Dexona tablets and injections are used to treat decreased adrenal gland function and inflammatory conditions like asthma and allergy.


Content on this page was last updated on 18 July, 2015, by Dr. Varun Gupta (MD Pharmacology)