Depnsaid MR 250mg/50mg/325mg Tablet is a combination medicine used in the treatment of pain due to muscle spasms. It improves the movement of muscles and provides relief from pain and discomfort associated with muscle spasms.

Depnsaid MR 250mg/50mg/325mg Tablet should be taken with food. This will prevent you from getting an upset stomach. You should take it regularly as advised by your doctor. Do not take more or use it for a longer duration than recommended by your doctor.

Using this medicine can cause some common side effects such as nausea, vomiting, heartburn, stomach pain, diarrhea, loss of appetite, and dryness in the mouth. If any of these side effects bother you or do not go away with time, you should let your doctor know. Your doctor may help with ways to reduce or prevent these side effects.

The medicine may not be suitable for everybody. Before taking it, let your doctor know if you have any problems with your heart, kidneys, or liver. To make sure it is safe for you, let your doctor also know all the other medicines you are taking. Pregnant and breastfeeding mothers should first consult their doctors before using the medicine.

Uses of Depnsaid MR Tablet

Treatment of Pain due to muscle spasm

Benefits of Depnsaid MR Tablet

In Treatment of Pain due to muscle spasm

Depnsaid MR 250mg/50mg/325mg Tablet is a combination medicine that is used to relieve pain, inflammation, and swelling in conditions that affect muscles. Also, it effectively relieves muscle stiffness or spasm, thereby improving muscle movement. It works by blocking chemical messengers in the brain that tell us we have pain.

Take it as it is prescribed to get the most benefit. Do not take more or longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Depnsaid MR Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Depnsaid MR

Nausea
Vomiting
Heartburn
Stomach pain
Diarrhea
Loss of appetite
Dryness in mouth
Indigestion
Skin rash

How to use Depnsaid MR Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Depnsaid MR 250mg/50mg/325mg Tablet is to be taken with food.

How Depnsaid MR Tablet works

Depnsaid MR 250mg/50mg/325mg Tablet is a combination of a muscle relaxant (Chlorzoxazone) and two pain relieving medicines (Diclofenac and Paracetamol). The muscle relaxant works on the centers in the brain and spinal cord to relieve muscle stiffness or spasm, thereby improving movement of muscles. The pain relieving medicines work by blocking the release of certain chemical messengers in the brain that cause pain and inflammation (redness and swelling).

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Depnsaid MR 250mg/50mg/325mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Depnsaid MR 250mg/50mg/325mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Depnsaid MR 250mg/50mg/325mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Depnsaid MR 250mg/50mg/325mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Depnsaid MR 250mg/50mg/325mg Tablet in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Depnsaid MR 250mg/50mg/325mg Tablet in patients with liver disease. Please consult your doctor.

What if you forget to take Depnsaid MR Tablet?

If you miss a dose of Depnsaid MR 250mg/50mg/325mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Depnsaid MR 250mg/50mg/325mg Tablet

₹5.53/Tablet

Intagesic-MR Tablet

Intas Pharmaceuticals Ltd

₹8.2/tablet

48% costlier

Dan-MR Tablet

Unison Pharmaceuticals Pvt Ltd

₹5.2/tablet

6% cheaper

Powergesic Tablet

Jenburkt Pharmaceuticals Ltd

₹13.9/tablet

151% costlier

Lobak Tablet

Geno Pharmaceuticals Ltd

₹8.6/tablet

56% costlier

Dicoliv MR 250 mg/50 mg/325 mg Tablet

Ind Swift Laboratories Ltd

₹7.65/tablet

38% costlier

View all substitutes

Quick tips

You have been prescribed Depnsaid MR 250mg/50mg/325mg Tablet to relieve pain due to muscle spasm.
This medicine is most effective when taken along with proper rest and physical therapy.
Avoid consuming alcohol when taking Depnsaid MR 250mg/50mg/325mg Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
Older adults may have increased drowsiness, confusion, and higher risk of falling as a result of taking Depnsaid MR 250mg/50mg/325mg Tablet.
Do not take it with any other medicine containing acetaminophen (drugs for pain/fever or cough-and-cold) without asking your doctor first.

Fact Box

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Patient concerns

Neck pain when I move my neck a bit. I think it's due to exercise and gyming .

Dr. Sunil Tripathi

Physiotherapy

It might be muscle soreness or muscle spasm due to improper Posture or overuse of musclesConsult a Physiotherapist in your area

sir/madam i have pain in my testical(in left side) it slept at 4am. when I woke up it was paining since 2 days it may be due to cold and there is no swelling. may be little bit.

Dr. Shyam Gupta

Obstetrics and Gynaecology

Hello PATIENT to 1mg. Your pain may be due to cold spasm or tortion. If pain persist please visit surgeon and examined.

User feedback

How much was the improvement?

Average

100%

What were the side-effects while using Depnsaid MR 250mg/50mg/325mg Tablet?

Body ache

100%

FAQs

What is Depnsaid MR 250mg/50mg/325mg Tablet?

Depnsaid MR 250mg/50mg/325mg Tablet is a combination of three medicines: Diclofenac, Paracetamol, and Chlorzoxazone. This medication helps in relieving muscle pain. Chlorzoxazone is a muscle relaxant which works by acting on the central nervous system. Diclofenac and Paracetamol work by lowering the chemical substance (prostaglandins) in the body that causes pain and inflammation.

Is it safe to use Depnsaid MR 250mg/50mg/325mg Tablet?

Depnsaid MR 250mg/50mg/325mg Tablet is safe for most of the patients. However, in some patients it may cause common side effects like nausea, vomiting, heartburn, stomach pain, diarrhea, loss of appetite, dryness in the mouth, weakness, sleepiness and other uncommon or rare side effects. Inform your doctor as soon as possible if you experience any persistent problem due to the medication.

Can I stop taking Depnsaid MR 250mg/50mg/325mg Tablet when my pain is relieved?

Depnsaid MR 250mg/50mg/325mg Tablet should be continued if advised for a specific time duration by your doctor. However, it can be discontinued if you are using it for short-term pain relief.

Can the use of Depnsaid MR 250mg/50mg/325mg Tablet cause nausea and vomiting?

Yes, the use of Depnsaid MR 250mg/50mg/325mg Tablet can cause nausea and vomiting. In case, you experience nausea while taking this medicine, take it with milk, food or with antacids. Avoid taking fatty or fried foods along with this medication. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to your doctor.

Can the use of Depnsaid MR 250mg/50mg/325mg Tablet cause dizziness?

Yes, the use of Depnsaid MR 250mg/50mg/325mg Tablet can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for sometime and resume once you feel better.

Can the use of Depnsaid MR 250mg/50mg/325mg Tablet cause damage to kidneys?

Yes, the long-term use of Depnsaid MR 250mg/50mg/325mg Tablet can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protect them from damage. Use of painkillers lowers the levels of prostaglandins in the body leading to kidney damage on long-term use. Use of painkillers is not recommended to patients with underlying kidney disease.

Can I take a higher than the recommended dose of this medicine?

No, taking a higher than the recommended dose of Depnsaid MR 250mg/50mg/325mg Tablet can increase the risks of side effects. If you are experiencing increased severity of pain or if the pain is not relieved by the recommended doses, please consult your doctor for re-evaluation.

What are the recommended storage conditions for Depnsaid MR 250mg/50mg/325mg Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Diclofenac. Rouse Boulevard, Philadelphia: Iroko Pharmaceuticals; 1998 [revised Oct. 2013]. [Accessed 02 Apr. 2019] (online) Available from:
Paracetamol. Barnstaple, Devon: Actavis UK Limited; 1980 [revised 23 Dec. 2016]. [Accessed 02 Apr. 2019] (online) Available from:
ScienceDirect. Chlorzoxazone. [Accessed 02 Apr. 2019] (online) Available from:
Diclofenac. Daventry, Northamptonshire: Dexcel Pharma Ltd.; 1996 [revised 20 Dec. 2017]. [Accessed 02 Apr. 2019] (online) Available from:
ScienceDirect. Paracetamol. [Accessed 02 Apr. 2019] (online) Available from:
Federal Register. Determination That PARAFLEX (Chlorzoxazone) Tablets, 250 Milligrams, Was Not Withdrawn From Sale for Reasons of Safety or Effectiveness. 2013. [Accessed 16 Sep. 2024] (online) Available from:

Marketer details

Name: Canvarzys Healthcare Ltd

Address: Ii Floor, Royal Plaza, College Road, Near Fountain Chowk, College Road, Ludhiana, Punjab 141001

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.