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D-Peg Plus Syrup

Written By Dr. Subita Alagh, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 02 Jan 2026 | 10:33 PM (IST)
D-Peg Plus Syrup is a combination medicine used in the treatment of constipation. The medicine works by drawing water into the intestines and softening the stool, which promotes bowel movements. It also helps in maintaining electrolyte balance and neutralizing stomach acid.
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General Information

Contains

Potassium Chloride (0.046mg)+ Sodium Chloride (0.35mg)+ Sodium Bicarbonate (0.17mg)+ Polyethylene Glycol (13.125mg)

Marketer

Delvin Formulations Pvt Ltd

Storage

Store below 30°C
The content is shown in English
D-Peg Plus Syrup image
D-Peg Plus Syrup image
D-Peg Plus Syrup image

Product introduction

Take D-Peg Plus Syrup in the dose and duration as advised by the doctor. The dose you are given will depend on the severity of your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen.


The medicine is usually safe with little or no side effects. However, let your doctor know if you experience any symptoms on taking the medicine. Lifestyle modifications like having a fiber-rich diet, increasing fluid intake, and regular exercise can help you to get better results.


Before taking this medicine, let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine. You should also tell your doctor if you have any liver diseases so that your doctor can prescribe a suitable dose for you. D-Peg Plus Syrup is generally considered safe to be used during pregancy or breastfeeding.

Uses of D-Peg Plus Syrup

Benefits of D-Peg Plus Syrup

Treatment of Constipation
D-Peg Plus Syrup provides relief from constipation by softening the stool, increasing its volume, and facilitating easier passage through the intestines. Use it in the exact dose and duration advised by the doctor for maximum benefits.

Side effects of D-Peg Plus Syrup

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of D-Peg Plus
  • Limited data available

How to use D-Peg Plus Syrup

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. D-Peg Plus Syrup may be taken with or without food.

How D-Peg Plus Syrup works

D-Peg Plus Syrup contains potassium chloride, sodium chloride, sodium bicarbonate, and polyethylene glycol. Potassium chloride works by raising potassium levels in your blood. Sodium chloride is a purified salt solution which works by replenishing salt and electrolyte levels in the body. Sodium bicarbonate is an alkalizer. It works by increasing the pH of blood and urine, thereby correcting metabolic acidosis (high acid levels in the body). It also speeds up the removal of toxic substances from the body in certain types of poisoning. In case of excessive fluid loss (such as in diarrhea), it works by replenishing salt and electrolyte levels. Polyethylene glycol works by drawing water into the intestine through osmosis, which makes the stool soft and easier to pass. It also helps clean out the intestines prior to medical procedures or examination.

Quick tips

  • Take D-Peg Plus Syrup exactly as advised by your doctor, typically after dissolving the contents in the prescribed amount of water. Do not take it directly without mixing it with water, as it may irritate your stomach or cause an electrolyte imbalance.
  • Drink plenty of clear fluids (like water or clear soups) along with medicine to prevent dehydration and support the bowel cleansing or rehydration process, depending on the intended use.
  • Do not eat solid food for at least 2 hours before and after taking D-Peg Plus Syrup, especially if it is being used for bowel preparation before a procedure like a colonoscopy.
  • Stop taking this medicine and contact your doctor if you feel bloated, nauseous, vomit persistently, or experience dizziness or irregular heartbeat. These may indicate fluid or electrolyte disturbances.
  • Mix D-Peg Plus Syrup freshly each time and use immediately. Do not store any leftover prepared medicine, as it may lose its effectiveness or become unsafe to consume.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with D-Peg Plus Syrup. Please consult your doctor.
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
D-Peg Plus Syrup is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of D-Peg Plus Syrup during breastfeeding is not available. Please consult your doctor.
Driving

Driving

SAFE
D-Peg Plus Syrup does not usually affect your ability to drive.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of D-Peg Plus Syrup in patients with kidney disease. Please consult your doctor.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of D-Peg Plus Syrup in patients with liver disease.

Frequently asked questions

D-Peg Plus Syrup is used as a bowel cleanser for colonoscopy procedures, certain bowel surgeries, and other bowel examinations. It helps empty the intestines by causing watery stools, making it easier for doctors to examine the colon.
You must mix the D-Peg Plus Syrup with lukewarm water to make 4 liters of clear solution. Drink 240 mL (about 1 glass) every 10 minutes until the full volume is consumed or your stool becomes watery and clear. The solution should never be taken as dry powder or mixed with flavored drinks unless advised by the doctor.
No. Do not take other oral medications within 1 hour of drinking the D-Peg Plus Syrup, as they may not be absorbed properly. Inform your doctor about all medications, especially those that affect kidneys, heart rhythm, or fluid balance.
Individuals should not take D-Peg Plus Syrup if they have intestinal blockage (ileus), bowel perforation, toxic colitis, severe kidney or heart problems, or known allergy to PEG or any of the ingredients present in D-Peg Plus Syrup.
Yes, you may have a light breakfast and clear liquids earlier in the day before you consume D-Peg Plus Syrup. Avoid red or purple-colored drinks, dairy, or solid foods. After starting the prep, drink only clear fluids up to 2 hours before the colonoscopy.
You may have your first bowel movement within 1 hour after drinking D-Peg Plus Syrup. Continue drinking the solution until your stool is clear and watery, which means your bowel is fully cleaned.
Yes. D-Peg Plus Syrup can cause loss of body fluids and essential salts, leading to dehydration, kidney problems, or irregular heartbeat. Drink plenty of clear fluids during the prep, and stop if you feel faint, dizzy, or very weak.
If you vomit and cannot keep drinking D-Peg Plus Syrup, stop drinking temporarily. Try again after a short break. If vomiting continues, contact your doctor as you may need an alternative preparation method.

Fact Box

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL

References

  1. Swartz ML. NuLYTELY (PEG 3350, sodium chloride, sodium bicarbonate and potassium chloride for oral solution). Gastroenterol Nurs. 1992 Feb;14(4):200-3. [Accessed 02 Jan. 2026]. Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Delvin Formulations Pvt Ltd
Address: New No:25, 12th Cross Street, Shastri Nagar, Adyar, Chennai - 600020

Vendor Details

Country of origin: India

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