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Coflin Syrup

Written By Dr. Syeda Aafia, MBA, BDS
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS
Last updated on 07 Apr 2026 | 03:08 PM (IST)
Coflin Syrup is a combination medicine used to treat cough with mucus. It thins mucus in the nose, windpipe and lungs, making it easier to cough out. It also provides relief from runny nose, watery eyes and throat irritation.
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General Information

Contains

Ambroxol (NA)+ Guaifenesin (NA)+ Chlorpheniramine Maleate (NA)+ Phenylephrine (NA)

Marketer

A. Menarini India Pvt Ltd

Storage

Store below 30°C
The content is shown in English
Coflin Syrup image
Coflin Syrup image

Product introduction

Coflin Syrup is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are nausea, vomiting, diarrhea, stomach upset, stomach pain, loss of appetite, headache, and rash. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine may cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can make dizziness worse.

Never support self-medication or recommend your medicine to another person. It is beneficial to have plenty of fluids while taking this medication. Before you start taking this medicine it is important to inform your doctor if you are suffering from liver or kidney disease. You should tell your doctor if you are pregnant or planning a pregnancy.

Uses of Coflin Syrup

Benefits of Coflin Syrup

Treatment of Cough with mucus
Coflin Syrup helps to loosen thick mucus, making it easier to cough out. This makes it easier for air to move in and out. It will also relieve allergy symptoms like watery eyes, sneezing, runny nose or throat irritation and help you carry out your daily activities more easily.

This medicine is safe and effective. It usually starts to work within a few minutes and the effects can last up to several hours. Take it as prescribed by the doctor. Do not stop using it unless you are advised to by your doctor. Taking this medicine enables you to live your life more freely without worrying so much about things that set off your symptoms.

Side effects of Coflin Syrup

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Coflin
  • Nausea
  • Vomiting
  • Diarrhea
  • Upset stomach
  • Stomach pain
  • Loss of appetite
  • Headache
  • Rash

How to use Coflin Syrup

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Coflin Syrup may be taken with or without food.

How Coflin Syrup works

Coflin Syrup is a combination of four medicines: Ambroxol, guaifenesin, chlorpheniramine and phenylephrine. Ambroxol is a mucolytic which thins and loosens mucus (phlegm), making it easier to cough out. Guaifenesin is an expectorant which works by decreasing the stickiness of mucus (phlegm) and helps in their removal from the airways. Chlorpheniramine is an antiallergic which relieves allergy symptoms like runny nose, watery eyes and sneezing. Phenylephrine is a decongestant which narrows the small blood vessels providing relief from congestion or stuffiness in the nose.

Quick tips

  • Coflin Syrup is prescribed to get relief from cough with mucus.
  • Drink warm water to help loosen the congestion and lubricate your throat while you are taking this medication.
  • Take exactly as directed by your doctor or on the label. Do not increase the dosage or take for longer than is recommended. 
  • In general, most coughs do not last more than 2 weeks. If your cough does last longer than this then it's better to see your doctor.
  • Inform your doctor if you have a history of stomach ulcers or asthma.
  • Inform your doctor if you are taking any other medications, e.g., anti-depressants.

Safety advice

Alcohol

Alcohol

UNSAFE
Do not drink alcohol while you are taking this medicine. Coflin Syrup may cause excessive drowsiness when taken with alcohol.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Coflin Syrup is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Coflin Syrup may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Coflin Syrup may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Coflin Syrup should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Use of Coflin Syrup may cause excessive sleepiness in patients with end stage kidney disease.
Liver

Liver

CAUTION
Coflin Syrup should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Fact Box

Habit Forming

No

Therapeutic Class

RESPIRATORY

Related lab tests

Complete Blood Count

References

  1. ScienceDirect. Ambroxol. [Accessed 01 Apr. 2019] (online) Available from:
  2. ScienceDirect. Guaifenesin. [Accessed 01 Apr. 2019] (online) Available from:
  3. Chlorpheniramine. Brentford, Middlesex: GlaxoSmithKline Consumer Healthcare; 1997 [revised 12 Apr. 2016]. [Accessed 01 Apr. 2019] (online) Available from:
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User feedback

Dry cough
60%
Cough
30%
Others
10%
Average
61%
Poor
28%
Excellent
11%
No Side Effect
17%
Drowsiness
17%
Fatigue
17%
Upset stomach
17%
Nausea
17%
With food
50%
With or without food
50%
Not Expensive
56%
Average
44%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: A. Menarini India Pvt Ltd
Address: 2102, Tower 3, Indiabulls Finance Center, Senapati Bapat Marg, Elphinstone Road (west), Mumbai - 400013

Vendor Details

Country of origin: India

Lab tests offered by us

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