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Product introduction
Barriga O 4mg/20mg Tablet is a combinational medicine commonly used to control nausea and vomiting due to certain medical conditions like stomach upset. It is also used to treat heartburn, acid reflux and problems in your food pipe.
Barriga O 4mg/20mg Tablet can be taken with or without food. How much you need, and how often you take it, will depend on what you are being treated for. Follow the advice of your doctor. You should keep taking it regularly to prevent problems from happening in the future. You may be able to help improve your symptoms by eating smaller meals more often and avoiding spicy or fatty foods.
Most people who take it do not have any side effects, but the most common include headache, constipation and diarrhea. If you do get a side effect, it is usually mild and will go away when you stop taking this medicine or as you adjust to it. Consult your doctor if any of these side effects bother you or do not go away.
Before taking it, you should tell your doctor if you have any kidney or liver problems. This may affect the dose or suitability of this medicine. Also, tell your doctor what other medicines you are taking as some may affect, or be affected by, this medicine. If you are pregnant or breastfeeding, ask advice from your doctor.
Barriga O 4mg/20mg Tablet blocks the action of chemicals in the body that can make you feel or be sick. This medicine helps you feel better and at ease. It is given as an injection by a doctor and you should follow the doctor’s instructions carefully to get the most benefit from this medicine.
In Gastroesophageal reflux disease (Acid reflux)
Gastroesophageal reflux disease (GERD) is a chronic (long-term) condition which is like having heartburn consistently rather than just occasionally. It happens because a muscle above your stomach relaxes too much and allows stomach contents to come back up into your esophagus and mouth. Barriga O 4mg/20mg Tablet reduces the amount of acid your stomach makes and relieves the pain associated with heartburn and acid reflux. You should take it exactly as it is prescribed for it to be effective.
Some simple lifestyle changes can help reduce the symptoms of GERD. Think about what foods trigger heartburn and try to avoid them; eat smaller, more frequent meals; try to lose weight if you are overweight and try to find ways to relax. Do not eat within 3-4 hours of going to bed.
Side effects of Barriga O Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Barriga O
Nausea
Vomiting
Pain
Sore throat
Infection
Abdominal pain
Headache
Constipation
Fatigue
Diarrhea
How to use Barriga O Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Barriga O 4mg/20mg Tablet may be taken with or without food.
How Barriga O Tablet works
Barriga O 4mg/20mg Tablet is a combination of two medicines: Ondansetron and Rabeprazole. Ondansetron is an antiemetic medication. It works by blocking the action of a chemical messenger (serotonin) in the brain that may cause nausea and vomiting. Rabeprazole is a proton pump inhibitor (PPI) which works by reducing the amount of acid in the stomach which helps in the relief of acid-related indigestion and heartburn.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Barriga O 4mg/20mg Tablet
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Barriga O 4mg/20mg Tablet during pregnancy is not available. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Barriga O 4mg/20mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Barriga O 4mg/20mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney
CONSULT YOUR DOCTOR
There is limited data available on the use of Barriga O 4mg/20mg Tablet in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited data available on the use of Barriga O 4mg/20mg Tablet in patients with liver disease.
What if you forget to take Barriga O Tablet?
If you miss a dose of Barriga O 4mg/20mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
Barriga O 4mg/20mg Tablet is used to give relief from nausea, vomiting as well as acidity, heartburn and other discomfort associated with acid reflux and peptic ulcer disease.
It is advisable to take your doses about half an hour before meals.
If you vomit within one hour of taking a dose, take another dose.
Avoid taking soft drinks, citrus fruits like orange and lemon, which can irritate the stomach and increase acid secretion.
Incorporate the following lifestyle changes in order to prevent acidity:
Make sure you eat regular meals and drink plenty of water.
Avoid spicy and fatty fried food.
Lose weight if you are obese.
If you are a smoker, consider giving up.
Don't drink too much alcohol.
Do not go to bed immediately after taking a meal. Sit in a relaxed position for sometimes for better digestion.
Fact Box
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Patient concerns
Gastric nausea vomiting reflux
Dr. Pushkar Mani
Physician
sompraz D 40 mg twice daily 1 hour before meal for 10 days
Heartburn Mental disorder Depression Frequent persistent heartburn Gastroesophageal reflux disease Irritable bowel syndrome Indigestion Back flow of acid from stomach Difficulty in swallowing Inflammation of esophagus Excess acid secretion by stomach Intestinal or stomach ulcers
Dr. Sunil Sekhri
Diabetology
You need to be examined in clinic to reach a diagnosis and then appropriate medicine can be prescribed
My cough is not getting cured since 4-6 months. Tried some doctors, their medicines work for some time and the dry cough starts again. Though it happens occasionally, but i still cough
Dr. Shubhra Chandan Pradhan
ENT
It can be allergic cough or acid reflux disease. Can't give more opinion without seeing
Barriga O 4mg/20mg Tablet is used to relieve nausea and vomiting caused by conditions such as an upset stomach. It is also helpful in treating heartburn, acid reflux, and other problems related to the food pipe (esophagus).
Is Barriga O 4mg/20mg Tablet used for GERD or ulcers when I also feel queasy or vomit?
Yes, Barriga O 4mg/20mg Tablet supports reflux/ulcer care while also calming nausea, which can make it easier to keep food and medicines in stomach and not vomit out.
I get morning heartburn and feel sick after meals. Can Barriga O 4mg/20mg Tablet help?
Many patients take Barriga O 4mg/20mg Tablet when reflux‑related nausea is worst around meals. Your doctor will tailor the timing and duration of your routine.
Will Barriga O 4mg/20mg Tablet help protect my stomach while I am on other treatments that upset it?
Barriga O 4mg/20mg Tablet is commonly used when treatments irritate the stomach, combining nausea relief with acid reduction to improve comfort and adherence.
How soon might day‑to‑day symptoms start improving during Barriga O 4mg/20mg Tablet treatment?
People often notice a calmer stomach and reduced queasiness within a day or two of using Barriga O 4mg/20mg Tablet. Full benefit for reflux/ulcer symptoms builds over days to weeks as your plan continues.
Can I keep using my usual reflux lifestyle steps with Barriga O 4mg/20mg Tablet?
Yes. Small regular meals, avoiding trigger foods, and elevating the head of the bed complement the Barriga O 4mg/20mg Tablet and often improve results further.
What if my nausea or heartburn does not settle after a couple of weeks of using Barriga O 4mg/20mg Tablet?
If your nausea or heartburn doesn’t improve after using Barriga O 4mg/20mg Tablet for a couple of weeks, inform your doctor. Share details such as when the symptoms occur, what triggers them, and how severe they are. Your doctor may adjust the dose or timing of your medicine, or check for other possible causes like infection, bile reflux, or side effects from other medications.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
Sharkey KA, MacNaughton WK. Gastrointestinal Motility and Water Flux, Emesis, and Biliary and Pancreatic Disease. In: Brunton LL, Hilal-Dandan R, Knollmann BC (Editors). Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 13th ed. New York, NY: McGraw-Hill Education; 2018. pp. 922-944.
Hoogerwerf WA, Pasricha PJ. Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 967-981.
McQuaid KR. Drugs Used in the Treatment of Gastrointestinal Diseases. In: Katzung BG, Masters SB, Trevor AJ (Editors). Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 1067-1101.
Rabeprazole and ondansetron. Pune, Maharashtra: Epione Pharmaceuticals Pvt. Ltd.; [Accessed 05/11/2025] (online) Available from:
Marketer details
Name: Veasley Pharmaceuticals Private Limited
Address: UNIT A9 GROUND FLOOR, INDUSTRIAL PLOT NO. 362 PHASE-1, PANCHKULA PANCHKULA Panchkula HR 134113 IN