Product introduction
Demfo 120mg Capsule is a medicine used in the treatment of multiple sclerosis (MS). It works by suppressing the inflammation and immune system that causes nerve damage in MS and helps reduce the worsening of the condition. However, it is not a cure for MS.
Demfo 120mg Capsule should be taken as advised by the doctor. You may take it with food to avoid an upset stomach. You may need to get regular blood and urine tests to monitor your blood cells, and kidney and liver function during treatment with this medicine. Take it regularly to get the most benefit from it. To help you remember, take it at the same time each day and do not stop taking until you have completed your dose.
Some common side effects of this medicine include flushing, abdominal pain, diarrhea, nausea, vomiting, indigestion, gastritis, increased liver enzymes, and rash. If you experience any of these side effects that do not go away or get worse, let your doctor know. They may be able to suggest ways to prejudice or prevent them.
Before using this medicine, tell your doctor if you have low white blood cell counts or an infection. Let your doctor also know of all the medical conditions and about the medicines you are taking to make sure it is safe for you. Pregnant and breastfeeding women should consult their doctor first before using this medicine as it may cause harmful effects to the developing baby.
Uses of Demfo Capsule
Benefits of Demfo Capsule
In Treatment of Multiple sclerosis (MS)
Multiple sclerosis is a long-term condition in which the body’s immune system mistakenly attacks the protective covering of nerves, leading to problems with movement, vision, and coordination. Demfo 120mg Capsule helps lower the frequency of relapses and slows down the progression of nerve damage. This supports better control of MS symptoms and helps patients maintain daily functioning and quality of life.
Side effects of Demfo Capsule
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Demfo
- Vomiting
- Diarrhea
- Nausea
- Abdominal pain
- Indigestion
- Stomach inflammation
- Increased liver enzymes
- Rash
- Flushing (sense of warmth in the face, ears, neck and trunk)
How to use Demfo Capsule
Take this medicine in the dose and duration as advised by your doctor. Demfo 120mg Capsule should be taken with or after food.
How Demfo Capsule works
Demfo 120mg Capsule is an Nrf2 activator. It works by suppressing inflammation and immune response that cause nerve damage in multiple sclerosis.
Safety advice
Alcohol
CAUTION
Alcohol should be used with caution while taking Demfo 120mg Capsule.
Pregnancy
UNSAFE
Demfo 120mg Capsule is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Demfo 120mg Capsule during breastfeeding is not available. Please consult your doctor.
Driving
SAFE
Demfo 120mg Capsule does not usually affect your ability to drive.
Kidney
CAUTION
Demfo 120mg Capsule should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver
CAUTION
Demfo 120mg Capsule should be used with caution in patients with severe liver disease. Dose adjustment may be needed.
What if you forget to take Demfo Capsule?
If you miss a dose of Demfo 120mg Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Demfo 120mg Capsule
₹80.14/Capsule
Tecfidera 120mg Capsule
Eisai Pharmaceuticals India Pvt Ltd
₹1325.71/capsule
1554% costlier
Quick tips
- Demfo 120mg Capsule helps treat multiple sclerosis.
- Take it with food to avoid an upset stomach.
- Do not chew, crush or break the tablets as they have a special coating to help prevent irritation of your stomach.
- Do not consume alcohol while taking this medicine as it may worsen the side effects.
- Your doctor may get regular blood and urine tests done to monitor your blood cells, kidney and liver function during treatment with this medicine.
- Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.
- Do not take Demfo 120mg Capsule if you are pregnant or breastfeeding. Use a reliable contraceptive method to prevent pregnancy.
Fact Box
Chemical Class
Fatty acid esters
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Oral Immunomodulators (Multiple Sclerosis)
Patient concerns
FAQs
What is Demfo 120mg Capsule used for?
Demfo 120mg Capsule is used to treat relapsing‑remitting multiple sclerosis (MS) in adults and children aged 13 years and older. It helps reduce the frequency of MS relapses and may slow disease progression.
Who should not take Demfo 120mg Capsule?
Individuals should not take Demfo 120mg Capsule if they are allergic to dimethyl fumarate or any ingredient in the medicine, or if they have suspected or confirmed progressive multifocal leukoencephalopathy (PML), a rare and serious brain infection.
What is PML, and how does Demfo 120mg Capsule relate to it?
Progressive multifocal leukoencephalopathy (PML) is a rare, potentially fatal brain infection caused by a virus. Cases have been reported in patients taking Demfo 120mg Capsule, especially those with low white blood cell counts (lymphopenia). Your doctor will monitor your blood counts regularly to reduce this risk.
Can Demfo 120mg Capsule cause low white blood cell counts?
Yes. Demfo 120mg Capsule can lower lymphocyte counts, which may increase infection risk. Your doctor will check your blood before starting treatment and every 3 months during therapy. Treatment may be stopped if your counts drop too low for more than 6 months.
What serious side effects of Demfo 120mg Capsule require immediate medical attention?
Serious side effects of Demfo 120mg Capsule include PML (new weakness, vision changes, confusion, personality changes), severe allergic reactions (swelling, breathing trouble, rash), or symptoms of liver problems (yellowing skin or eyes, severe stomach pain).
Are there any kidney or liver concerns with Demfo 120mg Capsule?
Yes. Demfo 120mg Capsule may cause kidney changes and liver enzyme elevations. Your doctor will check your kidney and liver function before you start and periodically during treatment. Use with caution if you have severe kidney or liver disease.
Can I get infections like shingles while taking Demfo 120mg Capsule?
Yes. Herpes zoster (shingles) infections have been reported while taking Demfo 120mg Capsule. Tell your doctor immediately if you develop painful blisters, rash, burning skin, or flu‑like symptoms, especially if you have low white blood cell counts.
Can Demfo 120mg Capsule cause flushing or stomach problems?
Yes. Flushing (redness, warmth) and gastrointestinal side effects (diarrhea, nausea, stomach pain) are very common, especially in the first month of Demfo 120mg Capsule treatment. Taking the medicine with food can help reduce these effects. Your doctor may temporarily lower the dose.
What is Fanconi syndrome, and can Demfo 120mg Capsule cause it?
Fanconi syndrome is a rare kidney disorder that has been reported with fumarate‑containing medicines such as Demfo 120mg Capsule. Symptoms include increased urination, thirst, muscle weakness, or bone pain. Contact your doctor if you notice these signs, so testing can be done.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Tecfidera. Dimethyl fumarate. [Accessed 24 Jan. 2019] (online) Available from:
- Dimethyl fumarate. Cambridge: Biogen Idec Inc; 2013. [Accessed 22 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:
Marketer details
Name: Dr Reddy's Laboratories Ltd
Address: Dr. Reddy's Laboratories Ltd., Village Malpur, P.O.Bhud, Baddi, Dist. Solan, H.P.
Country of origin: India
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₹1122
Inclusive of all taxes
MRP₹1218.75 8% OFF
14.0 capsules in 1 strip
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