
Jaundice

Jaundice is a condition characterized by yellowish discoloration of the skin, sclera (whites of the eyes), and mucous membranes resulting from the accumulation of excessive amounts of bilirubin. Bilirubin is a waste product that is made during the normal breakdown of hemoglobin. It passes through the liver and is eventually excreted from the body. Excessive bilirubin is the result of increased production or impaired excretion.
The normal serum levels of bilirubin are less than 1mg/dl; however, peripheral yellowing of the eye sclera (also known as icterus), is seen when the bilirubin levels are as high as 3 mg/dl as sclerae have a high affinity for bilirubin due to their high elastin content. As the serum bilirubin levels increase, the skin will progressively discolor ranging from yellow to green. The green color is due to biliverdin, a type of bile pigment that gives the color.
Jaundice usually does not require treatment in adults. Treatment if required is mostly focussed on its underlying causes and complications. Jaundice can generally be managed with diet or lifestyle, but if the cause is severe, the individuals may need immediate surgical or long-term treatment.



