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Zucox Plus

Composition for Zucox Plus Products

Zucox Plus Products are primarily used for
Tuberculosis (TB)

Products for Zucox Plus

MRP₹58.51
Not Available

About Zucox Plus Products

uses

Uses of Zucox Plus Products

Rifampicin+Isoniazid is used in the treatment of tuberculosis.
side effects

Zucox Plus Products side effects

Common
Side Effects of Zucox Plus are Low blood platelets, Peripheral neuropathy (tingling and numbness of feet and hand), Nausea, Vomiting, Abdominal pain, Skin rash, Itching, Hepatitis (viral infection of liver), Dizziness, Lethargy.
Severe
Side Effects of Zucox Plus are Vertigo, Stevens-Johnson syndrome, Fever, Agranulocytosis (deficiency of granulocytes in the blood), Aplastic anemia, Deafness, Ringing in ear, Breast enlargement in male, Pseudomembranous colitis, Pseudoadrenal crisis, Acute renal failure, Toxic epidermal necrolysis, Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome, Hypoglycemia (low blood glucose level).

How Zucox Plus Products work

Rifampicin + Isoniazid is a combination of two antibiotics: Rifampicin + Isoniazid1 and Rifampicin + Isoniazid2, which treats tuberculosis (TB). Rifampicin + Isoniazid1 works by inactivating a bacterial enzyme (RNA-polymerase) which is required by TB bacteria to make essential proteins and to reproduce. Rifampicin + Isoniazid2 prevents these bacteria from forming their own protective covering. Together, they kill the bacteria and eradicate the infection.

In Depth Information for Zucox Plus Products

  • You have been prescribed Zucox Plus for the treatment of tuberculosis.
  • Finish the full course of the medication, even if you feel better. Stopping it early may make the infection come back.
  • Take it on an empty stomach, preferably at the same time everyday.
  • It may discolour your urine, sweat, saliva and tears a reddish-orange colour. This is normal and not harmful.
  • Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
  • Avoid drinking alcohol while taking Zucox Plus as this may increase the risk of side effects on the liver.
  • Use an alternative or additional contraceptive method (such as condoms or a diaphragm) to prevent pregnancy while you are taking Zucox Plus as it may make hormonal contraceptives such as the pill less effective.
  • Do not take indigestion remedies (antacids)  within at least two hours of taking Zucox Plus.

Patient Concerns about Zucox Plus Products

Frequently asked questions about Zucox Plus Products

Q. What is Zucox Plus 450 mg/300 mg Tablet?

Zucox Plus 450 mg/300 mg Tablet is a combination of two medicines: Rifampicin and Isoniazid. It is used in the treatment of tuberculosis. Rifampicin works by inactivating a bacterial enzyme (RNA-polymerase) which is required by tuberculosis bacteria to make essential proteins and reproduce. Isoniazid prevents the tuberculosis causing bacteria from forming their own protective covering. Together, they kill the bacteria and eradicate the infection.

Q. What is the most important information I should know about the Zucox Plus 450 mg/300 mg Tablet?

Take the proper course of drug that has been prescribed to you. Do not stop in between even if you begin to feel better. Avoid alcohol while taking this medicine as it increases the risk of damage to your liver during treatment. Tell your doctor immediately if you experience vision changes, loss of appetite, tiredness, stomach pain, nausea or vomiting, yellow skin or eyes or dark-colored urine.

Q. What is the best time to take Zucox Plus 450 mg/300 mg Tablet?

Take Zucox Plus 450 mg/300 mg Tablet exactly as directed by your doctor. It is best to take the medicine on an empty stomach one hour before or two hours after meals.

Q. Does Zucox Plus 450 mg/300 mg Tablet cause change in urine color/turn urine orange?

Yes, Zucox Plus 450 mg/300 mg Tablet can change the color of your urine (skin, sweat, saliva, tears and feces) to brownish-red or orange. This effect is not harmful.

Q. Does the use of Zucox Plus 450 mg/300 mg Tablet make birth control pills ineffective?

Yes, Zucox Plus 450 mg/300 mg Tablet can make birth control pills less effective. So, ask the doctor about using a birth control method which does not affect your hormone levels (such as a condom, diaphragm and spermicide).

Q. What are the instructions for storage and disposal of Zucox Plus 450 mg/300 mg Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Information last updated by Dr. Varun Gupta, MD Pharmacology on 11th Jun 2025.
The medicine details are for information purpose only. Consult a doctor before taking any medicine.