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Trumab

Composition for Trumab Products

Trumab Products are primarily used for
Breast cancer, Stomach cancer

Products for Trumab

Trumab 440mg Injection
vial of 1 Powder for infusion
MRP₹15021.63
Not Available
Trumab 150mg Injection
vial of 1 Injection
MRP₹7442.81
Not Available

About Trumab Products

uses

Uses of Trumab Products

Trastuzumab is used in the treatment of breast cancer and stomach cancer.
side effects

Trumab Products side effects

Common
Side Effects of Trumab are Chills, Diarrhea, Fever, Headache, Nausea, Back pain, Vomiting, Weakness, Breathlessness.

How Trumab Products work

Trastuzumab is a recombinant IgG1 monoclonal antibody. It works against the HER2 (human epidermal growth factor receptor protein) receptors which are responsible for the over-proliferation of cancer cells in breast cancer and stomach cancer cells. It destroys the cancer cells by inhibiting HER2. It also inhibits various cancer-causing downstream signaling pathways.

In Depth Information for Trumab Products

  • It is given as an injection into your vein or under the skin, usually over 1 hour.
  • Use effective contraception method to prevent pregnancy while taking this medicine and for 7 months after you stop the treatment. 
  • Your doctor will monitor your heart regularly while taking this medicine. Inform your doctor if you notice symptoms such as breathlessness, cough, shivering, swelling of legs and arm.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. 

Patient Concerns about Trumab Products

Frequently asked questions about Trumab Products

Q. What are the serious side effects of Trumab 440mg Injection?

There are various side effects related to Trumab 440mg Injection such as sore throat, fever, chills, excessive tiredness, pale skin, nosebleeds, and other unusual bruising or bleeding. One can also experience stomach pain, seizures, hallucinations, muscle cramps, and spasms. Along with that, nausea or vomiting, loss of appetite, fatigue, rapid heart beat, discoloration of urine; decreased amount of urine, difficulty in urinating, pain when urinating, and other signs of infection can also be observed with the use of Trumab 440mg Injection. You should call your doctor immediately if you notice any such symptoms.

Q. How long after Trumab 440mg Injection therapy can I get pregnant?

Women of child-bearing age should use effective contraception during Trumab 440mg Injection therapy and for 7 months after completing the treatment. You can plan your pregnancy after 7 months of treatment with Trumab 440mg Injection.

Q. How long should Trumab 440mg Injection be taken?

Patients with early breast cancer should take Trumab 440mg Injection for 1 year or until disease recurs, whichever occurs first. It is not advised to extend the treatment beyond 1 year in patients of early breast cancer.

Q. Is fasting required before administering Trumab 440mg Injection?

No, fasting is not required before administering Trumab 440mg Injection. It should be given under the guidance of a doctor who is experienced in giving cancer chemotherapy and should be given only by a healthcare professional.

Q. How is Trumab 440mg Injection given, intravenously or intramuscularly?

There are 2 different formulations available for administration of Trumab 440mg Injection, one is given as an infusion into a vein (intravenous infusion) and the other is given as an injection under the skin (subcutaneous injection). It is important to check the product labels to ensure that the correct formulation is being given as prescribed. Trumab 440mg Injection intravenous formulation is not for subcutaneous use and should be given as an intravenous infusion only. Your doctor may consider switching your Trumab 440mg Injection intravenous treatment to Trumab 440mg Injection subcutaneous treatment (and vice versa) if considered appropriate for you.

Q. Can Trumab 440mg Injection be given to HER2 negative cancer patients?

No, Trumab 440mg Injection cannot be given in patients with HER2 negative cancer cells. Trumab 440mg Injection belongs to class of monoclonal antibody. It binds selectively to a protein called human epidermal growth factor receptor 2 (HER2). HER2 is found, in large amounts, on the surface of some cancer cells. When Trumab 440mg Injection binds to HER2, it stops the growth and spread of the cancer cells. Therefore, it is only effective in HER2 positive patients (in which HER2 is present) and will not be beneficial for HER2 negative patients (in which HER2 is not present).

Q. Why has my doctor advised for investigations of heart?

Trumab 440mg Injection when used with anthracycline class of anti-cancer medicines (eg doxorubicin) may adversely affect your heart. Hence, your doctor needs to check the health of your heart initially before starting treatment and during treatment.

Q. How frequently heart investigations are required?

Heart investigations should be performed at the starting of the treatment. It should be repeated every 3 months during treatment and every 6 months after the discontinuation of treatment until 24 months from the last administration of Trumab 440mg Injection. Those patients who already have heart-related problems will require investigations every 12 weeks.
Information last updated by Dr. Varun Gupta, MD Pharmacology on 25th Nov 2025.
The medicine details are for information purpose only. Consult a doctor before taking any medicine.