Isotretinoin is a derivative of vitamin A. It acts on glands (sebaceous) to reduce the production of a natural substance (sebum) that causes acne. Also, the controlled sebum production kills acne-causing bacteria. It also works as an anti-inflammatory to decrease inflammation (redness and swelling).
Q. What are the recommended tests during Tretz 10 Capsule therapy?
Your liver enzymes and serum lipids will be checked before the treatment is started. These levels will also be monitored 1 month after the start of treatment and subsequently at 3 monthly intervals unless more frequent monitoring is clinically indicated.
Q. Is Tretz 10 Capsule safe to use?
Tretz 10 Capsule should be used with care since it is associated with significant adverse reactions. It should be used only for patients with severe nodular acne who are unresponsive to conventional therapy, including systemic antibiotics. In addition, Tretz 10 Capsule should not be used by pregnant women because it can cause severe birth defects.
Q. Is Tretz 10 Capsule a steroid?
No, Tretz 10 Capsule is a retinoid (vitamin A) which is used to treat severe types of acne.
Q. Does Tretz 10 Capsule work permanently?
It has been observed in many patients that a single 15-20-week course effectively cures the condition and prevents it from coming back. If at all a second course is required, one should wait for at least 8 weeks after completion of the first course. This is because experience with Tretz 10 Capsule has shown that the symptoms in the patients with acne may continue to improve following treatment with Tretz 10 Capsule.
Q. Why is Tretz 10 Capsule so dangerous during pregnancy?
If pregnancy occurs during treatment with Tretz 10 Capsule then, there is an extremely high risk that the baby may be born with severe birth defects.
Q. Can Tretz 10 Capsule cause cancer?
No, there are no reports of Tretz 10 Capsule causing cancer. In fact, it may be useful in some forms of head, skin and neck cancers.
Q. What are the long-term side effects of Tretz 10 Capsule?
A normal course of treatment of Tretz 10 Capsule is 15–20 weeks. Therefore, long-term effects of low doses have not been studied. However, it may have some effect on the bone mineral density. It may decrease bone mineral density in some patients, resulting in osteoporosis or fractures.
Q. Does Tretz 10 Capsule affect male fertility?
No, Tretz 10 Capsule does not affect the fertility of male patients. No significant effects were seen on ejaculate volume, sperm count, total sperm motility, morphology or seminal plasma fructose.
Q. Does Tretz 10 Capsule damage your liver?
There may be a transient increase in liver enzymes with Tretz 10 Capsule use. Therefore, regular laboratory tests are required. These values generally return to normal after some time. If the levels remain elevated for a long time, your doctor may discontinue the use of Tretz 10 Capsule.
Information last updated by Dr. Varun Gupta, MD Pharmacology on 10th Aug 2020. The medicine details are for information purpose only. Consult a doctor before taking any medicine.